Emerging treatment strategies in wound care

Article Dermatology

Cold Plasma Treatment Promotes Full-thickness Healing of Skin Wounds in Murine Models

Joon M. Jung et al.

Summary: Cold plasma has a positive effect on promoting skin wound healing by accelerating the healing process and increasing the expression of related genes. The results of both in vivo and in vitro experiments support this conclusion.

INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS (2023)

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Article Chemistry, Multidisciplinary

pH/Glucose Dual Responsive Metformin Release Hydrogel Dressings with Adhesion and Self-Healing via Dual-Dynamic Bonding for Athletic Diabetic Foot Wound Healing

Yongping Liang et al.

Summary: A dual-responsive hydrogel dressing was constructed for the treatment of type II diabetic foot ulcers and shown to promote wound healing in a rat model. The addition of metformin and graphene oxide further enhanced wound repair.

ACS NANO (2022)

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Article Materials Science, Composites

Effectively exerting the reinforcement of polyvinyl alcohol nanocomposite hydrogel via poly(dopamine) functionalized graphene oxide

Elnaz Famkar et al.

Summary: The study demonstrated that both types of PDA can act as a coupling agent and significantly improve viscoelastic and mechanical properties through hydrogen bonds and pi-pi interactions with composite components. Additionally, PDA enhanced interfacial adhesion in PVA-GO, leading to excellent self-healing properties.

COMPOSITES SCIENCE AND TECHNOLOGY (2022)

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Article Chemistry, Applied

Silver/poly(vinyl alcohol)/graphene hydrogels for wound dressing applications: Understanding the mechanism of silver, antibacterial agent release

Katarina Nesovic et al.

Summary: This study aimed to analyze silver release from electrochemically synthesized antibacterial silver nanoparticles loaded poly(vinyl alcohol) hydrogels for wound dressing applications, showing potential in antibacterial activity assessment against Staphylococcus aureus and Escherichia coli bacterial strains.

JOURNAL OF VINYL & ADDITIVE TECHNOLOGY (2022)

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Article Materials Science, Biomaterials

Platelet rich fibrin containing nanofibrous dressing for wound healing application: Fabrication, characterization and biological evaluations

Marjan Mirhaj et al.

Summary: Nanofibrous structures have shown great potential for medical applications. In this study, a Polycaprolactone/Keratin/Platelet-rich fibrin (PCL/Kr/PRF) fibrous scaffold fabricated through electrospinning was evaluated for wound healing. The scaffold exhibited smaller fiber diameter, increased antibacterial activity, and accelerated wound healing process. This study suggests that PCL/Kr/PRF could be a suitable candidate for wound healing and skin regeneration.

BIOMATERIALS ADVANCES (2022)

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Article Biochemistry & Molecular Biology

Fabrication and evaluation of Cs/PVP sponge containing platelet-rich fibrin as a wound healing accelerator: An in vitro and in vivo study

Mohamadreza Tavakoli et al.

Summary: The study developed a freeze-dried chitosan/polyvinylpyrrolidone sponge with the addition of platelet-rich fibrin (PRF) as a wound dressing. The addition of 1% PRF significantly improved the mechanical properties of the sponge and showed effective antibacterial activity. The release of growth factors from PRF and the increased proliferation and angiogenic potential of cells were observed.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

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Review Dermatology

Negative-pressure wound therapy for donor-site closure in radial forearm free flap: A systematic review and meta-analysis

Kazuki Shimada et al.

Summary: This systematic review evaluated the efficacy of NPWT with skin graft for donor-site closure in radial forearm free flap (RFFF) reconstruction. The study found that while NPWT improved hand functionality earlier, it did not lead to significant improvements in partial skin graft loss, tendon exposure, and other complications compared to conventional bolster dressing.

INTERNATIONAL WOUND JOURNAL (2022)

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Article Materials Science, Multidisciplinary

Microspheres powder as potential clinical auxiliary materials for combining with platelet-rich plasma to prepare cream gel towards wound treatment

Haiyang Yu et al.

Summary: This study developed a microspheres powder that can form a gel cream when combined with platelet-rich plasma (PRP), promoting wound healing. The PRP-granular gel can be spread evenly on the wound area due to its permeability and electrostatic action. It alters the gene expression and changes the process of wound healing.

APPLIED MATERIALS TODAY (2022)

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Editorial Material Dermatology

Platelet-rich plasma injection and becaplermin gel as effective dressing adjuvants for treating chronic nonhealing ulcers in patients with junctional epidermolysis bullosa

Saurabh Singh et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2021)

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Review Dermatology

Evidence-Based Review of Antibiofilm Agents for Wound Care

Maximillian A. Weigelt et al.

Summary: There is a need for more high-quality clinical studies to explore the beneficial role of biofilm eradication and its impact on wound healing. Currently available wound care products show varying efficacy in destroying biofilms. Future directions include the development of novel therapeutic strategies and noninvasive techniques to quantify biofilms.

ADVANCES IN WOUND CARE (2021)

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Article Engineering, Biomedical

Novel application of autologous micrografts in a collagen-glycosaminoglycan scaffold for diabetic wound healing

Adriana C. Panayi et al.

Summary: This study evaluated the efficacy of a novel collagen-GAG scaffold modified with autologous micrografts for wound healing in a murine model. The results showed that the group treated with the modified scaffold healed faster and exhibited better cellular proliferation, collagen deposition, and keratinocyte migration. These findings provide promising results for the development of a new therapeutic modality for wound repair.

BIOMEDICAL MATERIALS (2021)

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Article Gastroenterology & Hepatology

Hyperbaric oxygen therapy for the treatment of perianal fistulas in 20 patients with Crohn's disease

Corine A. Lansdorp et al.

Summary: This study revealed significant clinical, radiological, and biochemical improvements in Crohn's disease patients with therapy-refractory perianal fistulas after treatment with hyperbaric oxygen.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2021)

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Article Cell Biology

Platelets Facilitate the Wound-Healing Capability of Mesenchymal Stem Cells by Mitochondrial Transfer and Metabolic Reprogramming

Jennyfer Levoux et al.

Summary: Platelets enhance the therapeutic potential of MSCs by transferring mitochondria and promoting pro-angiogenic activity. Activation of the de novo fatty acid synthesis pathway is required for increased secretion of pro-angiogenic factors by platelet-preconditioned MSCs. Testing platelet mitochondria quality before clinical use is crucial for optimizing their effects.

CELL METABOLISM (2021)

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Article Biochemistry & Molecular Biology

Development of nanosilver doped carboxymethyl chitosan-polyamideamine alginate composite dressing for wound treatment

Mou Zhou et al.

Summary: The novel multi-functional platform dressing exhibited excellent performance in treating bacterial infected wounds, with synergistic effect of antibacterial property and wound healing.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

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Article Pharmacology & Pharmacy

Mesoporous silica incorporated PCL/Curcumin nanofiber for wound healing application

Saranya Rathinavel et al.

Summary: The composite nanoscaffold prepared through electrospinning shows potential for wound healing therapy, with high biocompatibility and antimicrobial properties, excellent cell adhesion, and achieving a 99% scar-less wound healing rate within 21 days in in vivo experiments.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

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Article Dermatology

Clinical and Economic Impact of Wound Care Using a Polyurethane Foam Multilayer Dressing

Veronica Tiscar-Gonzalez et al.

Summary: The study showed that the use of a newly introduced dressing significantly reduced the frequency of dressing changes, decreased wound area, lowered weekly costs, and improved satisfaction among both patients and providers, which could lead to a major improvement in efficiency and quality of wound care in routine clinical practice.

ADVANCES IN SKIN & WOUND CARE (2021)

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Review Biochemistry & Molecular Biology

Systematic Review: Adipose-Derived Mesenchymal Stem Cells, Platelet-Rich Plasma and Biomaterials as New Regenerative Strategies in Chronic Skin Wounds and Soft Tissue Defects

Pietro Gentile et al.

Summary: The number of clinical trials evaluating AD-MSCs, PRP, and biomaterials efficacy in regenerative plastic surgery has significantly increased in the past decade. These treatments show promise in treating soft tissue defects and chronic wounds without major side effects, highlighting their safety and effectiveness.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Article Cell & Tissue Engineering

Can Tissue Engineering Bring Hope to the Development of Human Tympanic Membrane?

Mina Aleemardani et al.

Summary: This review highlights the issues with traditional surgical treatment of the tympanic membrane (TM) and focuses on the emerging technology of tissue engineering and advanced materials in manufacturing the TM for clinical applications. The advancements include graphene as a 3D scaffold, stem cell technology with growth factors, and fabrication through 3D printing, making it a potential option for treating TM perforations. Research in tissue engineering for TM regeneration shows promise in overcoming the drawbacks of current surgical methods.

TISSUE ENGINEERING PART B-REVIEWS (2021)

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Article Materials Science, Coatings & Films

Electrophoretic deposition of graphene oxide reinforced hydroxyapatite on the tantalum substrate for bone implant applications: In vitro corrosion and bio-tribological behavior

Mahboobeh Mahmoodi et al.

Summary: In this study, graphene oxide/hydroxyapatite composite coating on tantalum substrate was achieved by electrophoretic deposition, enhancing hardness and corrosion resistance while reducing friction coefficient. The high surface roughness and wettability of the coating promoted the proliferation of MG-63 cells on the surface, suggesting potential for dental and orthopedic implant applications.

SURFACE & COATINGS TECHNOLOGY (2021)

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Editorial Material Dermatology

Minced Skin Grafting: A Minimally Invasive and Low-Cost Procedure to Treat Pyoderma Gangrenosum

Edoardo Cammarata et al.

Summary: Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis that is challenging to treat, with skin grafts and amputation considered as last resorts. Minimally invasive autologous grafts, such as minced micrografts, could be an effective alternative for ulcer healing in patients with PG, promoting granulation tissue formation and reducing the risk of pathergy. This method is cost-effective and does not require complex surgical techniques, making it a valuable addition to the treatment arsenal for improving the quality of life of patients with PG.

ADVANCES IN SKIN & WOUND CARE (2021)

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Review Chemistry, Multidisciplinary

Carbon Nanotubes-Based Hydrogels for Bacterial Eradiation and Wound-Healing Applications

Tejal V. Patil et al.

Summary: Biocompatible nanomaterials, particularly carbon nanotubes (CNTs), have superior antimicrobial, adhesive, and mechanical properties that make them suitable for wound-healing and antibacterial applications. The conductivity of CNTs is significantly influenced by their structure, temperature, and functionalization, while surface functionalization can easily modify their properties to enhance antibacterial potential.

APPLIED SCIENCES-BASEL (2021)

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Article Biochemistry & Molecular Biology

Ag@MOF-loaded chitosan nanoparticle and polyvinyl alcohol/sodium alginate/chitosan bilayer dressing for wound healing applications

Meng Zhang et al.

Summary: This study successfully prepared a bilayer composite dressing for wound healing, with the upper layer possessing antibacterial activity and the lower layer having biocompatibility, the combination of which showed synergistic antibacterial effects and could accelerate wound healing.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

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Review Biochemistry & Molecular Biology

Cold Plasma Systems and Their Application in Surface Treatments for Medicine

Francisco L. Tabares et al.

Summary: This paper provides a review of cold plasma setups and the processes involved in generating active species. The focus is on the interaction between cold plasmas and materials used in medical applications, highlighting the significant impact on the surface properties of biomaterials. The elemental processes responsible for changes in physio-chemical properties of surfaces when exposed to plasma are described, with examples of ongoing research given to illustrate the current state-of-the-art at a conceptual level.

MOLECULES (2021)

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Article Hematology

Autologous platelet-rich plasma in the treatment of refractory wounds in cutaneous leukocytoclastic vasculitis complicated with hypertension (grade 2 moderate risk): A case report

Zhongmei Yi et al.

Summary: Cutaneous leukocytoclastic vasculitis is an inflammatory skin condition characterized by a variety of skin rashes, including erythema, purpura, and ulcers. Treatment using autologous platelet-rich plasma gel can effectively reduce wound size and promote healing.

TRANSFUSION AND APHERESIS SCIENCE (2021)

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Article Multidisciplinary Sciences

Negative pressure wound therapy does not decrease postoperative wound complications in patients undergoing mastectomy and flap fixation

L. De Rooij et al.

Summary: This study compared postoperative wound complications in patients undergoing mastectomy with or without NPWT and found that the NPWT group had a slightly higher rate of complications compared to the control group, and there was no significant difference in unplanned visits or development of clinically significant seromas between the two groups.

SCIENTIFIC REPORTS (2021)

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Review Chemistry, Multidisciplinary

Graphene Oxide: Opportunities and Challenges in Biomedicine

Pariya Zare et al.

Summary: Graphene oxide (GO) has exceptional physicochemical and biological properties, making it highly promising for biomedical applications. Recent studies have focused on GO-based materials (GOBMs) and their significance in biomedical applications, indicating great interest from academia, pharmaceutical, and biomedical industries.

NANOMATERIALS (2021)

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Review Materials Science, Multidisciplinary

3-Dimensional Printing of Hydrogel-Based Nanocomposites: A Comprehensive Review on the Technology Description, Properties, and Applications

Sanaz Soleymani Eil Bakhtiari et al.

Summary: The increasing demand for customized implants and tissue scaffolds has led to a need for advanced biomaterials and fabricating processes for creating complex 3D structures resembling the extracellular matrix. Biofabrication approaches like cell-laden hydrogel 3D printing are becoming more popular for developing 3D functional environments similar to natural tissues and organs. While hydrogels can regulate cellular behavior, their inferior mechanical properties pose a challenge in maintaining and enhancing the mechanical integrity of fabricated scaffolds for 3D structures.

ADVANCED ENGINEERING MATERIALS (2021)

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Article Pharmacology & Pharmacy

Bioengineering for curcumin loaded carboxymethyl guargum/reduced graphene oxide nanocomposites for chronic wound healing applications

Prabhakar Orsu et al.

Summary: The study reported on the fabrication and characterization of nanostructured CMGG and rGO composite dressings loaded with curcumin for chronic wound healing. In vitro studies showed 100% wound closure within 48 hours and controlled drug release, while in vivo results demonstrated the potential wound healing effects of the nanocomposite. Histological studies indicated that the biomimetic CMGG nanofibers have excellent healing effects on chronic wounds.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Review Chemistry, Multidisciplinary

Nanomaterials applied in wound healing: Mechanisms, limitations and perspectives

Menglei Wang et al.

Summary: Wounds on the skin can be caused by internal and external factors, creating challenges for clinicians in terms of infections, nonhealing chronic wounds, and aesthetic and functional recovery. The development of nanotechnology in biomedicine has introduced new materials and methods for wound treatment and holds great potential for intelligent healing.

JOURNAL OF CONTROLLED RELEASE (2021)

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Article Cell Biology

Diabetic wound healing: The impact of diabetes on myofibroblast activity and its potential therapeutic treatments

Rou Wan et al.

Summary: Diabetes is a systemic disease that affects the body's ability to regulate blood sugar levels, leading to complications such as chronic non-healing wounds, which can significantly impact patients' quality of life. Scientific studies have shown that high glucose levels can interfere with fibroblast differentiation and myofibroblast function, affecting extracellular matrix production and wound contraction. Further research on potential treatments targeting these pathways is essential for improving wound healing in diabetic patients.

WOUND REPAIR AND REGENERATION (2021)

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Review Chemistry, Multidisciplinary

Applications of Nanosized-Lipid-Based Drug Delivery Systems in Wound Care

Andreea-Mariana Matei et al.

Summary: Impaired wound healing is a significant public health issue, prompting the need for developing new therapies. Nanotechnology offers a promising approach to enhance treatment efficacy and manage wounds by addressing issues such as drug permeability and bioavailability. This paper focuses on the application of nanosized-lipid-based drug delivery systems in wound care, highlighting their potential benefits in comparison to conventional treatments.

APPLIED SCIENCES-BASEL (2021)

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Article Materials Science, Multidisciplinary

Highly osteogenic and mechanically strong nanofibrous scaffolds based on functionalized multi-walled carbon nanotubes-reinforced electrospun keratin/poly(ε-caprolactone)

Mahboobeh Mahmoodi et al.

Summary: The addition of CNTs-COOH to PCL/Kr scaffold significantly improved its mechanical properties and osteogenic characteristics, resulting in reduced fiber diameter, increased specific surface area, and enhanced osteoconductivity. The PCL/Kr/CNT scaffold showed excellent osteogenic differentiation in simulated body fluid and promoted mineral formation on the scaffold's surface for mesenchymal stem cells.

MATERIALS TODAY COMMUNICATIONS (2021)

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Review Biochemistry & Molecular Biology

Modern Wound Dressings: Hydrogel Dressings

Valentin Brumberg et al.

Summary: This article discusses the treatment of chronic wounds and the application of related dressings, focusing on the advantages of hydrogels and comparing them with other technologies.

BIOMEDICINES (2021)

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Article Medicine, General & Internal

Platelet-rich fibrin: Basics of biological actions and protocol modifications

Voja Pavlovic et al.

Summary: Platelet-rich fibrin (PRF), as a second-generation platelet concentrate, has gained increasing attention in regenerative treatments. Despite conflicting data on the potential effects of PRF components on wound healing, its autologous preparation, low cost, and prolonged growth factor release provide significant advantages. This review aims to clarify the physiological effects of certain PRF components and provide insights into new developmental approaches.

OPEN MEDICINE (2021)

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Article Medicine, Legal

THE USE OF CADAVERIC SKIN ALLOGRAFTS IN THE MANAGEMENT OF EXTENSIVE WOUNDS

Liliana Gabriela Popa et al.

Summary: Skin grafting is crucial in managing extensive wounds, with cadaveric skin allografts being the preferred temporary coverage option due to their ability to reduce fluid and protein loss, improve thermoregulation, lower pain and infection risk, and enhance subsequent autograft success. However, challenges such as limited availability, high antigenicity, infection transmission risk, and optimization of processing and storage techniques need to be addressed in future research.

ROMANIAN JOURNAL OF LEGAL MEDICINE (2021)

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Article Cell Biology

Fish skin grafts compared to human amnion/chorion membrane allografts: A double-blind, prospective, randomized clinical trial of acute wound healing

Robert S. Kirsner et al.

WOUND REPAIR AND REGENERATION (2020)

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Article Surgery

Fat Graft Enhanced With Adipose-Derived Stem Cells in Aesthetic Breast Augmentation: Clinical, Histological, and Instrumental Evaluation

Pietro Gentile et al.

AESTHETIC SURGERY JOURNAL (2020)

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Article Dentistry, Oral Surgery & Medicine

Alvogyl and absorbable gelatin sponge as palatal wound dressings following epithelialized free gingival graft harvest: a randomized clinical trial

Karim Ehab et al.

CLINICAL ORAL INVESTIGATIONS (2020)

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Review Biochemistry & Molecular Biology

New Nanotechnologies for the Treatment and Repair of Skin Burns Infections

Eliana B. Souto et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Article Critical Care Medicine

The Optimal Treatment for Partial Thickness Burns: A Cost-Utility Analysis of Skin Allograft vs. Topical Silver Dressings

Clifford C. Sheckter et al.

JOURNAL OF BURN CARE & RESEARCH (2020)

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Article Critical Care Medicine

Initial Experience With Autologous Skin Cell Suspension for Treatment of Deep Partial-Thickness Facial Burns

Joseph A. Molnar et al.

JOURNAL OF BURN CARE & RESEARCH (2020)

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Review Chemistry, Applied

Alginate-based composite materials for wound dressing application:A mini review

Kokkarachedu Varaprasad et al.

CARBOHYDRATE POLYMERS (2020)

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Review Chemistry, Applied

Wound healing and antimicrobial effect of active secondary metabolites in chitosan-based wound dressings: A review

Arash Moeini et al.

CARBOHYDRATE POLYMERS (2020)

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Article Dentistry, Oral Surgery & Medicine

Comparison of the effects of injectable platelet-rich fibrin and autologous fibrin glue applications on palatal wound healing: a randomized controlled clinical trial

Mehmet Kiziltoprak et al.

CLINICAL ORAL INVESTIGATIONS (2020)

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Article Biochemistry & Molecular Biology

Incorporation of chitosan/graphene oxide nanocomposite in to the PMMA bone cement: Physical, mechanical and biological evaluation

Mohamadreza Tavakoli et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

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Article Medicine, General & Internal

Burn injury

Marc G. Jeschke et al.

NATURE REVIEWS DISEASE PRIMERS (2020)

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Article Dermatology

Cryopreserved human skin allografts promote angiogenesis and dermal regeneration in a murine model

Dominic Henn et al.

INTERNATIONAL WOUND JOURNAL (2020)

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Article Surgery

Negative Pressure Wound Therapy vs Conventional Wound Treatment in Subcutaneous Abdominal Wound Healing Impairment The SAWHI Randomized Clinical Trial

Dorthe Seidel et al.

JAMA SURGERY (2020)

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Article Dermatology

Using cold plasma to treat warts in children: A case series

Peter C. Friedman et al.

PEDIATRIC DERMATOLOGY (2020)

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Article Gastroenterology & Hepatology

Wound healing of metastatic perineal Crohn's disease using hyperbaric oxygen therapy: A case series

Corine A. Lansdorp et al.

UNITED EUROPEAN GASTROENTEROLOGY JOURNAL (2020)

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Review Biochemistry & Molecular Biology

Systematic Review: Allogenic Use of Stromal Vascular Fraction (SVF) and Decellularized Extracellular Matrices (ECM) as Advanced Therapy Medicinal Products (ATMP) in Tissue Regeneration

Pietro Gentile et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Review Pharmacology & Pharmacy

Skin Wound Healing Process and New Emerging Technologies for Skin Wound Care and Regeneration

Erika Maria Tottoli et al.

PHARMACEUTICS (2020)

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Review Biotechnology & Applied Microbiology

Targeting Tunable Physical Properties of Materials for Chronic Wound Care

Yuzhen Wang et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

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Article Medicine, General & Internal

Effect of Cold Atmospheric Plasma Therapy vs Standard Therapy Placebo on Wound Healing in Patients With Diabetic Foot Ulcers A Randomized Clinical Trial

Bernd Stratmann et al.

JAMA NETWORK OPEN (2020)

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Article Biotechnology & Applied Microbiology

Regenerative application of stromal vascular fraction cells enhanced fat graft maintenance: clinical assessment in face rejuvenation

Pietro Gentile et al.

EXPERT OPINION ON BIOLOGICAL THERAPY (2020)

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Article Medicine, General & Internal

Wool-derived keratin dressings versus usual care dressings for treatment of slow healing venous leg ulceration: a randomised controlled trial (Keratin4VLU)

Andrew Jull et al.

BMJ OPEN (2020)

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Review Polymer Science

Polymethyl Methacrylate-Based Bone Cements Containing Carbon Nanotubes and Graphene Oxide: An Overview of Physical, Mechanical, and Biological Properties

Sanaz Soleymani Eil Bakhtiari et al.

POLYMERS (2020)

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Article Multidisciplinary Sciences

Deciphering the secretome of leukocyte-platelet rich fibrin: towards a better understanding of its wound healing properties

Lidia Hermida-Nogueira et al.

SCIENTIFIC REPORTS (2020)

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Article Medicine, General & Internal

Use of a new cold plasma tool for psoriasis treatment: A case report

Clarice Gareri et al.

SAGE OPEN MEDICAL CASE REPORTS (2020)

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Article Polymer Science

Evaluation of physical, mechanical, and biodegradation of chitosan/graphene oxide composite as bone substitutes

Mohamadreza Tavakoli et al.

POLYMER-PLASTICS TECHNOLOGY AND MATERIALS (2020)

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Article Endocrinology & Metabolism

Beneficial effects of cold atmospheric plasma on inflammatory phase of diabetic foot ulcers; a randomized clinical trial

Mohammad Reza Amini et al.

JOURNAL OF DIABETES AND METABOLIC DISORDERS (2020)

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Article Critical Care Medicine

Use of Tilapia Skin as a Xenograft for Pediatric Burn Treatment: A Case Report

Bruno Almeida Costa et al.

JOURNAL OF BURN CARE & RESEARCH (2019)

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Article Critical Care Medicine

Scar Quality of Skin Graft Borders: A Prospective, Randomized, Double-Blinded Evaluation

Kevin J. Zuo et al.

JOURNAL OF BURN CARE & RESEARCH (2019)

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Review Chemistry, Physical

Nanomaterials for Wound Healing and Infection Control

Mara Madalina Mihai et al.

MATERIALS (2019)

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Article Surgery

Minced Skin Grafting for Promoting Wound Healing and Improving Donor-Site Appearance after Split-Thickness Skin Grafting: A Prospective Half-Side Comparative Trial

Toru Miyanaga et al.

PLASTIC AND RECONSTRUCTIVE SURGERY (2019)

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Review Dermatology

A Critical Review and Perspective of Honey in Tissue Engineering and Clinical Wound Healing

Katherine R. Nixon et al.

ADVANCES IN WOUND CARE (2019)

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Article Endocrinology & Metabolism

Collagen dressing in the treatment of diabetic foot ulcer: A prospective, randomized, placebo-controlled, single-center study

Kwang Hwan Park et al.

DIABETES RESEARCH AND CLINICAL PRACTICE (2019)

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Review Biochemistry & Molecular Biology

Impact of the Different Preparation Methods to Obtain Human Adipose-Derived Stromal Vascular Fraction Cells (AD-SVFs) and Human Adipose-Derived Mesenchymal Stem Cells (AD-MSCs): Enzymatic Digestion Versus Mechanical Centrifugation

Pietro Gentile et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

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Article Engineering, Biomedical

Preparation of ADM/PRP freeze-dried dressing and effect of mice full-thickness skin defect model

Xiaoxuan Lei et al.

BIOMEDICAL MATERIALS (2019)

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Article Immunology

Interleukin-36γ-producing macrophages drive IL-17-mediated fibrosis

Sven D. Sommerfeld et al.

SCIENCE IMMUNOLOGY (2019)

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Article Critical Care Medicine

A randomized, double-blind, phase I clinical trial of fetal cell-based skin substitutes on healing of donor sites in burn patients

Mahnoush Momeni et al.

BURNS (2019)

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Review Biochemistry & Molecular Biology

Chitosan based-asymmetric membranes for wound healing: A review

Sonia P. Miguel et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

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Article Engineering, Biomedical

Preparation of self-regulating/anti-adhesive hydrogels and their ability to promote healing in burn wounds

Min Liang et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2019)

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Article Dentistry, Oral Surgery & Medicine

Bone Regeneration of Canine Peri-implant Defects Using Cell Sheets of Adipose-Derived Mesenchymal Stem Cells and Platelet-Rich Fibrin Membranes

Lidan Ding et al.

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY (2019)

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Article Medicine, General & Internal

Evaluate the effects of platelet rich plasma (PRP) and zinc oxide ointment on skin wound healing

Barham Jalal Abdullah et al.

ANNALS OF MEDICINE AND SURGERY (2019)

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Article Surgery

A randomized clinical trial comparing a collagen-based composite dressing versus topical antibiotic ointment on healing full-thickness skin wounds to promote epithelialization

Hsin-Chung Tsai et al.

FORMOSAN JOURNAL OF SURGERY (2019)

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Article Dermatology

Chitosan-based biocompatible dressing for treatment of recalcitrant lesions of cutaneous leishmaniasis: A pilot clinical study

Fahimeh Abdollahimajd et al.

INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY (2019)

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Article Nursing

Three Cases Describing Outcomes of Negative-Pressure Wound Therapy With Instillation for Complex Wound Healing

Kimberly Dawn Hall et al.

JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING (2019)

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Article Cell Biology

White cell and platelet content affects the release of bioactive factors in different blood-derived scaffolds

S. Cabaro et al.

PLATELETS (2018)

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Article Cell Biology

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