期刊
ANNUAL REVIEW OF CHEMICAL AND BIOMOLECULAR ENGINEERING
卷 13, 期 -, 页码 481-499出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev-chembioeng-092220-015404
关键词
3D printing; bioprinting; bioink; vasculature
This article focuses on the application of three-dimensional printing in the medical field and discusses the strengths and weaknesses of different types of printers. It also explores the challenges and future opportunities in tissue engineering using 3D printing.
Three-dimensional printing is a still-emerging technology with high impact for the medical community, particularly in the development of tissues for the clinic. Many types of printers are under development, including extrusion, droplet, melt, and light-curing technologies. Herein we discuss the various types of 3D printers and their strengths and weaknesses concerning tissue engineering. Despite the advantages of 3D printing, challenges remain in the development of large, clinically relevant tissues. Advancements in bioink development, printer technology, tissue vascularization, and cellular sourcing/expansion are discussed, alongside future opportunities for the field. Trends regarding in situ printing, personalized medicine, and whole organ development are highlighted.
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