期刊
WASTE MANAGEMENT
卷 144, 期 -, 页码 19-28出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.wasman.2022.03.008
关键词
Antibiotic; Antibiotic resistance gene; Age; Seasonal variation; Heavy metal; Leachate
资金
- National Natural Science Foundation of China [51878617, 51678531, 41977331, 51778579, 21876165]
Landfill leachate is a significant source and recipient of antibiotics and antibiotic resistance genes. The composition and concentration of these compounds are influenced by factors such as leachate age, seasonal variation, heavy metal concentrations, and leachate quality parameters.
Landfill leachate is an important source and sink of antibiotics and antibiotic resistance genes (ARGs), which poses a potential threat to human health and ecological environment. Ten antibiotics and 8 ARGs in leachates collected from Zhejiang Province, China, were systematically investigated. The effects of multiple factors were considered: leachate age, season when the leachate was sampled (dry or rainy), heavy metal concentrations, and leachate quality parameters. Leachate age was crucial to the profile of the detectable antibiotics and ARGs. The total concentration of antibiotics were in the order of macrolides > sulfonamides > tetracyclines and they decreased significantly with leachate age. Similarly, fewer ARGs were harbored in aged leachate; the order of abundance of the ARGs was mexF (11.92 +/- 0.22 log10 gene copies/L) > sul2 > Intl1 > sul1 > ermB > mefA > tetM > tetQ (9.57 +/- 1.32 log(10) gene copies/L). The extreme abundances (i.e., the maxima and minima) of ARGs relating to the same class of antibiotic were always surprisingly similar and appeared in leachate of the same age. Seasonal variation greatly affected the concentrations of antibiotics in the leachate-the concentration difference between the dry and rainy seasons could reach two orders of magnitude. Heavy metal concentrations and leachate quality parameters also had important effects on the distribution of antibiotics and ARGs. Overall, the profile of antibiotics and ARGs in leachates was influenced by numerous factors, and the pollution of antibiotics and ARGs may be reduced and controlled by adjusting the environmental factors.
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