4.6 Editorial Material

Tfh cells induce intratumoral tertiary lymphoid structures

期刊

TRENDS IN IMMUNOLOGY
卷 43, 期 4, 页码 274-276

出版社

CELL PRESS
DOI: 10.1016/j.it.2022.02.010

关键词

-

资金

  1. Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) [TRR 305]

向作者/读者索取更多资源

A recent study reveals that repression of Satb1 in CD4(+) T cells can drive intratumoral TLS formation, resulting in reduced tumor growth.
Tertiary lymphoid structures (TLS) are highly organized ectopic structures found in nonlymphoid organs under chronic inflammatory conditions, including cancer. A recent study by Chaurio et al. reports that repression of Satb1 in CD4(+) T cells can lead to increased Tfh cell differentiation, driving intratumoral TLS formation, resulting in reduced tumor growth in mice.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据