相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Increase in ADAR1p110 activates the canonical Wnt signaling pathway associated with aggressive phenotype in triple negative breast cancer cells
Fernanda Morales et al.
GENE (2022)
Transcriptome Profiling of ADAR1 Targets in Triple-Negative Breast Cancer Cells Reveals Mechanisms for Regulating Growth and Invasion
Allison R. Baker et al.
MOLECULAR CANCER RESEARCH (2022)
CircNEIL3 regulatory loop promotes pancreatic ductal adenocarcinoma progression via miRNA sponging and A-to-I RNA-editing
Peng Shen et al.
MOLECULAR CANCER (2021)
ADAR1 RNA editing enzyme regulates R-loop formation and genome stability at telomeres in cancer cells
Yusuke Shiromoto et al.
NATURE COMMUNICATIONS (2021)
Upregulation of ADAR Promotes Breast Cancer Progression and Serves as a Potential Therapeutic Target
Xiao Li et al.
Journal of Oncology (2021)
Targeting RNA editing of antizyme inhibitor 1: A potential oligonucleotide-based antisense therapy for cancer
Daryl Jin Tai Tay et al.
MOLECULAR THERAPY (2021)
Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence
Zhong Wu et al.
NATURE GENETICS (2021)
Decoupling expression and editing preferences of ADAR1 p150 and p110 isoforms
Tony Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
RNA editing at a limited number of sites is sufficient to prevent MDA5 activation in the mouse brain
Jung In Kim et al.
PLOS GENETICS (2021)
Aicardi-Goutieres syndrome-associated mutation at ADAR1 gene locus activates innate immune response in mouse brain
Xinfeng Guo et al.
JOURNAL OF NEUROINFLAMMATION (2021)
An ADAR1-dependent RNA editing event in the cyclin-dependent kinase CDK13 promotes thyroid cancer hallmarks
Julia Ramirez-Moya et al.
MOLECULAR CANCER (2021)
Double-stranded RNA-specific adenosine deaminase-knockdown inhibits the proliferation and induces apoptosis of DU145 and PC3 cells by promoting the phosphorylation of H2A.X variant histone
Xiezhao Li et al.
ONCOLOGY LETTERS (2021)
ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair
Sonia Jimeno et al.
NATURE COMMUNICATIONS (2021)
ADAR1 is a new target of METTL3 and plays a pro-oncogenic role in glioblastoma by an editing-independent mechanism
Valentina Tassinari et al.
GENOME BIOLOGY (2021)
Evaluating the therapeutic potential of ADAR1 inhibition for triple-negative breast cancer
Che-Pei Kung et al.
ONCOGENE (2021)
IL6R-STAT3-ADAR1 (P150) interplay promotes oncogenicity in multiple myeloma with 1q21 amplification
Phaik Ju Teoh et al.
HAEMATOLOGICA (2020)
ADAR1p150 regulates the biosynthesis and function of miRNA-149*in human melanoma
M. M. Yujie Ding et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)
Cis- and trans-regulations of pre-mRNA splicing by RNA editing enzymes influence cancer development
Sze Jing Tang et al.
NATURE COMMUNICATIONS (2020)
ADAR1-mediated RNA editing is a novel oncogenic process in thyroid cancer and regulates miR-200 activity
Julia Ramirez-Moya et al.
ONCOGENE (2020)
ADAR1 Transcriptome editing promotes breast cancer progression through the regulation of cell cycle and DNA damage response
Eduardo A. Sagredo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2020)
ADAR1 Suppresses Interferon Signaling in Gastric Cancer Cells by MicroRNA-302a-Mediated IRF9/STAT1 Regulation
Lushang Jiang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson et al.
NATURE (2020)
Advances in RNA cytosine-5 methylation: detection, regulatory mechanisms, biological functions and links to cancer
Chen Xue et al.
BIOMARKER RESEARCH (2020)
Circular RNA hsa_circ_0004872 inhibits gastric cancer progression via the miR-224/Smad4/ADAR1 successive regulatory circuit
Cunying Ma et al.
MOLECULAR CANCER (2020)
Activation of AZIN1 RNA editing is a novel mechanism that promotes invasive potential of cancer-associated fibroblasts in colorectal cancer
Sho Takeda et al.
CANCER LETTERS (2019)
ADAR1 promotes the epithelial-to-mesenchymal transition and stem-like cell phenotype of oral cancer by facilitating oncogenic microRNA maturation
Xue Liu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation
Qingfei Jiang et al.
CANCER CELL (2019)
Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
Jeffrey J. Ishizuka et al.
NATURE (2019)
Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss
Huayang Liu et al.
NATURE MEDICINE (2019)
The majority of A-to-I RNA editing is not required for mammalian homeostasis
Alistair M. Chalk et al.
GENOME BIOLOGY (2019)
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
Hachung Chung et al.
CELL (2018)
Tumor-associated intronic editing of HNRPLL generates a novel splicing variant linked to cell proliferation
Yi-Tung Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
ADAR1-mediated regulation of melanoma invasion
Yael Nemlich et al.
NATURE COMMUNICATIONS (2018)
A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression
Guermarie Velazquez-Torres et al.
NATURE COMMUNICATIONS (2018)
Adar3 Is Involved in Learning and Memory in Mice
Dessislava Mladenova et al.
FRONTIERS IN NEUROSCIENCE (2018)
Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis
Phaik Ju Teoh et al.
BLOOD (2018)
RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure
Mamta Jain et al.
EMBO JOURNAL (2018)
Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells
Hugh S. Gannon et al.
NATURE COMMUNICATIONS (2018)
AZIN1 RNA editing confers cancer stemness and enhances oncogenic potential in colorectal cancer
Kunitoshi Shigeyasu et al.
JCI INSIGHT (2018)
A-to-I RNA Editing Up-regulates Human Dihydrofolate Reductase in Breast Cancer
Masataka Nakano et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Dynamic landscape and regulation of RNA editing in mammals
Meng How Tan et al.
NATURE (2017)
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay
Masayuki Sakurai et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
An RNA editing/dsRNA binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancer
Lihua Qi et al.
NUCLEIC ACIDS RESEARCH (2017)
The RNA modification landscape in human disease
Nicky Jonkhout et al.
RNA (2017)
The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK
Elianna M. Amin et al.
SCIENCE SIGNALING (2017)
RNA editing of AZIN1 induces the malignant progression of non-small-cell lung cancers
Xueda Hu et al.
TUMOR BIOLOGY (2017)
Circular RNA expression is suppressed by androgen receptor (AR)-regulated adenosine deaminase that acts on RNA (ADAR1) in human hepatocellular carcinoma
Liang Shi et al.
CELL DEATH & DISEASE (2017)
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay
Masayuki Sakurai et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK
Elianna M. Amin et al.
SCIENCE SIGNALING (2017)
ADAR1 overexpression is associated with cervical cancer progression and angiogenesis
Ying Chen et al.
DIAGNOSTIC PATHOLOGY (2017)
RNA Editing Modulates Human Hepatic Aryl Hydrocarbon Receptor Expression by Creating MicroRNA Recognition Sequence
Masataka Nakano et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
A-to-I editing of coding and non-coding RNAs by ADARs
Kazuko Nishikura
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis
C. Anadon et al.
ONCOGENE (2016)
ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis
Maria Anna Zipeto et al.
CELL STEM CELL (2016)
ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer
Tim Hon Man Chan et al.
GASTROENTEROLOGY (2016)
Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation
Konstantinos Stellos et al.
NATURE MEDICINE (2016)
The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis
Kiranmai Gumireddy et al.
NATURE COMMUNICATIONS (2016)
Aberrant overexpression of ADAR1 promotes gastric cancer progression by activating mTOR/p70S6K signaling
Ning Dou et al.
ONCOTARGET (2016)
The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers
Leng Han et al.
CANCER CELL (2015)
PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and influences cell proliferation in gliomas
Bin Yang et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2015)
Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development
Kathleen Pestal et al.
IMMUNITY (2015)
Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis
Einav Shoshan et al.
NATURE CELL BIOLOGY (2015)
PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3
Ahmad Salameh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
RNA EDITING RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself
Brian J. Liddicoat et al.
SCIENCE (2015)
A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme
Gilli Galore-Haskel et al.
ONCOTARGET (2015)
Profiling RNA editing in human tissues: towards the inosinome Atlas
Ernesto Picardi et al.
SCIENTIFIC REPORTS (2015)
Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors
Nurit Paz-Yaacov et al.
CELL REPORTS (2015)
Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome
Debora Fumagalli et al.
CELL REPORTS (2015)
Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Yan-Ru Qin et al.
CANCER RESEARCH (2014)
A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma
Tim Hon Man Chan et al.
GUT (2014)
Novel ADAR1 mutations including a single amino acid deletion in the deaminase domain underlie dyschromatosis symmetrica hereditaria in Japanese families
Michihiro Kono et al.
INTERNATIONAL JOURNAL OF DERMATOLOGY (2014)
Hippocampus-specific deficiency in RNA editing of GluA2 in Alzheimer's disease
Inna Gaisler-Salomon et al.
NEUROBIOLOGY OF AGING (2014)
The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA
Niamh M. Mannion et al.
CELL REPORTS (2014)
A role of ADAR2 and RNA editing of glutamate receptors in mood disorders and schizophrenia
Mie Kubota-Sakashita et al.
MOLECULAR BRAIN (2014)
Potent and Selective Inhibition of A-to-I RNA Editing with 2′-O-Methyl/Locked Nucleic Acid-Containing Antisense Oligoribonucleotides
Rena A. Mizrahi et al.
ACS CHEMICAL BIOLOGY (2013)
ADAR1 Forms a Complex with Dicer to Promote MicroRNA Processing and RNA-Induced Gene Silencing
Hiromitsu Ota et al.
CELL (2013)
Deletion of the RNA-editing enzyme ADAR1 causes regression of established chronic myelogenous leukemia in mice
Richard A. Steinman et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth
Yael Nemlich et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma
Lei Lei Chen et al.
NATURE MEDICINE (2013)
Deciphering the functions and regulation of brain-enriched A-to-I RNA editing
Jin Billy Li et al.
NATURE NEUROSCIENCE (2013)
ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia
Qingfei Jiang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Global regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR)
Oz Solomon et al.
RNA (2013)
ADAR Regulates RNA Editing, Transcript Stability, and Gene Expression
Isabel X. Wang et al.
CELL REPORTS (2013)
Accurate identification of A-to-I RNA editing in human by transcriptome sequencing
Jae Hoon Bahn et al.
GENOME RESEARCH (2012)
Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells
Yukti Choudhury et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Mutations in ADAR1 cause Aicardi-Goutieres syndrome associated with a type I interferon signature
Gillian I. Rice et al.
NATURE GENETICS (2012)
Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons
Takuto Hideyama et al.
NEUROBIOLOGY OF DISEASE (2012)
Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral
Charles E. Samuel
VIROLOGY (2011)
Predicting sites of ADAR editing in double-stranded RNA
Julie M. Eggington et al.
NATURE COMMUNICATIONS (2011)
RNA editing of the serotonin 5HT2C receptor and its effects on cell signalling, pharmacology and brain function
Tim D. Werry et al.
PHARMACOLOGY & THERAPEUTICS (2008)
p150 ADAR1 isoform involved in maintenance of HeLa cell proliferation
Haifang Wang et al.
BMC CANCER (2006)
Two novel mutations and evidence for haploinsufficiency of the ADAR gene in dyschromatosis symmetrica hereditaria
Q Liu et al.
BRITISH JOURNAL OF DERMATOLOGY (2006)
Liver disintegration in the mouse embryo caused by deficiency in the RNA-editing enzyme ADAR1
JC Hartner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Underediting of glutamate receptor GluR-B mRNA in malignant gliomas
S Maas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2
M Higuchi et al.
NATURE (2000)
分享论文
