Bone marrow adipose tissue in metabolic health

Recent studies have highlighted the role of bone marrow adipose tissue (BMAT) as a regulator of skeletal homeostasis and energy metabolism. While long con -sidered an inert filler, occupying empty spaces from bone loss and reduced hematopoiesis, BMAT is now considered a secretory and metabolic organ that responds to nutritional challenges and secretes cytokines, which indirectly im-pact energy and bone metabolism. The recent advances in our understanding of the function of BMAT have been enabled by novel noninvasive imaging tech-niques, which allow longitudinal assessment of BMAT in vivo following interven-tions. This review will focus on the latest advances in our understanding of BMAT and its role in metabolic health. Imaging techniques to quantify the content and composition of BMAT will be discussed.

Automated summary

BMAT plays a crucial role in regulating skeletal homeostasis and energy metabolism. Recent studies have utilized novel imaging techniques to gain a better understanding of its function and its impact on metabolic health.