Heteroatom is not needed: Access to dibenzo[e,h][1,4]diazecin-9-ones from dibenzo[b,e]azepin-6-one via the hydrated imidazoline ring expansion (HIRE) approach

5,11-Dihydro-6H-dibenzo[b,e]azepin-6-ones were for the first time expanded into 5,7,8,14-tetrahy-drodibenzo[e,h][1,4]diazecin-9(6H)-ones via the so-called hydrated imidazoline ring expansion (HIRE). CO 2022 Elsevier Ltd. All rights reserved.

Automated summary

In this study, 5,11-Dihydro-6H-dibenzo[b,e]azepin-6-ones were successfully expanded into 5,7,8,14-tetrahydrodibenzo[e,h][1,4]diazecin-9(6H)-ones using the hydrated imidazoline ring expansion (HIRE) method.