期刊
SMALL
卷 18, 期 19, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/smll.202201223
关键词
biomarker detection; carbon dots; full-color room temperature phosphorescence; hydrogen bonds; photoinduced electron transfer
类别
资金
- NSFC [21875025]
- Innovation Research Group at Institutions of Higher Education in Chongqing [CXQT19027]
- Chongqing Talent Program
- Science and Technology Project of Banan District
- Innovation Support Plan for the Returned Overseas of Chongqing [cx2020052]
- Open Fund of Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates [2021-kllma-03]
This study presents a feasible strategy for achieving high stability and full-color long-lived room temperature phosphorescence (RTP) of carbon dots (CDs)-based composite materials in aqueous environment by constructing a rigid hydrogen bonds' network. The obtained m,p-CDs@CA composite materials exhibit excellent stability, dispersion, and long-lived RTP properties, making them desirable for biomarker detection.
Long-lived room temperature phosphorescence (RTP) materials are widely utilized in the field of biological and chemical sensing, due to their unique characteristics of long-lived luminescence and no background autofluorescence. However, the realization of full-color RTP in aqueous solution still remains a great challenge. Herein, a feasible strategy for achieving high stability and full-color RTP of carbon dots (CDs)-based composite materials in aqueous environment is reported by constructing a rigid hydrogen bonds' network. The obtained m,p-CDs@CA composite materials exhibit deep-blue RTP with phosphorescence quantum yield of 23.2% and lifetime of 1.74 s, and the afterglow can last for over 12 s. More importantly, the m,p-CDs@CA composite materials are desirable in the detection of biomarkers, because of excellent stability, dispersion, and long-lived RTP properties. The m,p-CDs@CA suspension also displays excellent sensitivity, and a limitation of detection as low as 5.61 and 550 nm for biomarkers 5-hydroxyindole-3-acetic acid (HIAA) and serotonin (5-hydroxytryptamine, HT), respectively. Meanwhile, the sensing performance exhibits excellent selectivity even in the presence of other competitive species in blood plasma and urine. With superior selectivity, the long-lived phosphorescence probe based on m,p-CDs@CA suspension can be as an effective biomarker for carcinoid identification, which has potential application in clinical analysis.
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