Serological diagnosis of strongyloidiasis in immunocompetent and immunosuppressed patients based on an electrochemical immunoassay using a flexible device allied to PLS-DA and ROC statistical tools

Article Biophysics

Magnetic beads combined with carbon black -based screen-printed electrodes for COVID-19: A reliable and miniaturized electrochemical immunosensor for SARS-CoV-2 detection in saliva

Laura Fabiani et al.

Summary: The study developed an electrochemical immunoassay for rapid and smart detection of SARS-CoV-2 coronavirus in saliva, with high sensitivity, rapid analysis (30 min), miniaturization, portability, and ease of use.

BIOSENSORS & BIOELECTRONICS (2021)

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Article Biochemistry & Molecular Biology

A novel signal amplification strategy electrochemical immunosensor for ultra-sensitive determination of p53 protein

Jian Kang et al.

Summary: In this study, a novel sandwich-type electrochemical immunosensor was developed for quantitative and ultra-sensitive determination of the tumor suppressor protein p53 using signal amplification strategies with PEDOT:PSS and AuNPs. The sensor showed a wide working range of 1-120 ng mL(-1) and a low detection limit of 0.09 ng mL(-1), demonstrating good recovery, high sensitivity, reliability, and selectivity.

BIOELECTROCHEMISTRY (2021)

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Article Materials Science, Multidisciplinary

Screen printed diamond electrode as efficient point-of-care platform for submicromolar determination of cytostatic drug in biological fluids and pharmaceutical product

Dalibor M. Stankovic et al.

Summary: This study introduces an advanced electrochemical platform based on screen printed diamond electrode system for single drop point-of-care testing, successfully applied for the quantification of doxorubicin hydrochloride in biological fluids and pharmaceutical products. The developed procedure can be easily implemented for pharmaceutical control and medical analysis in laboratory and field conditions.

DIAMOND AND RELATED MATERIALS (2021)

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Article Chemistry, Analytical

Label-free detection of vitamin D by optical biosensing based on long period fiber grating

Flavio Esposito et al.

Summary: This study presents a fiber optic biosensor for label-free detection of vitamin D3, showing good sensitivity and stability in both laboratory and complex media.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

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Article Chemistry, Analytical

Strongyloidiasis Serological Analysis with Three Different Biological Probes and Their Electrochemical Responses in a Screen-Printed Gold Electrode

Francielli C. C. Melo et al.

Summary: The study aimed to validate biological antigens for biomedical applications. Different probes were evaluated for detecting specific IgG in serum for human strongyloidiasis diagnosis, with D3 peptide showing the best electrochemical performance and potential for replacing whole antigen extracts from parasites in diagnosis.

SENSORS (2021)

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Review Chemistry, Analytical

Electrochemical biosensors for neglected tropical diseases: A review

Tais Aparecida Reis Cordeiro et al.

Summary: Neglected tropical diseases are a group of infectious and parasitic diseases prevalent in tropical and subtropical regions, with limited access to proper healthcare. The development of low-cost biosensors for fast diagnosis in these areas is crucial for better treatment and eradication. While progress has been made in the past decade, challenges remain in early detection of neglected tropical diseases using biosensors.

TALANTA (2021)

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Review Engineering, Electrical & Electronic

Label-Free Biosensors Based on Long Period Fiber Gratings: A Review

Flavio Esposito et al.

Summary: This paper presents a comprehensive review of the design, development, and testing of label-free biosensors based on in-fiber long period gratings. It focuses on optical transducers and methodologies that enhance sensitivity, as well as coating nanomaterials, bio-functionalization strategies, and recognition elements for selectivity. The aim is to provide an overview of the current state of LPG-based label-free biosensors and highlight future research trends.

IEEE SENSORS JOURNAL (2021)

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Article Electrochemistry