期刊
SENSORS
卷 22, 期 8, 页码 -出版社
MDPI
DOI: 10.3390/s22082862
关键词
learning from demonstration; kinesthetic teaching; sub-millimetre accuracy; mass spectrometry; MALDI; colony picking
资金
- Slovenian Research Agency [P2-0228]
This study demonstrates the feasibility of using collaborative robots in a medical microbiology laboratory for fine tasks, such as bacterial colony picking and identification. The results show that the system works similarly well as a manual operator, with an overall identification error rate of around 11%.
This study focuses on the feasibility of collaborative robot implementation in a medical microbiology laboratory by demonstrating fine tasks using kinesthetic teaching. Fine tasks require sub-millimetre positioning accuracy. Bacterial colony picking and identification was used as a case study. Colonies were picked from Petri dishes and identified using matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometry. We picked and identified 56 colonies (36 colonies of Gram-negative Acinetobacter baumannii and 20 colonies of Gram-positive Staphylococcus epidermidis). The overall identification error rate was around 11%, although it was significantly lower for Gram-positive bacteria (5%) than Gram-negative bacteria (13.9%). Based on the identification scores, it was concluded that the system works similarly well as a manual operator. It was determined that tasks were successfully demonstrated using kinesthetic teaching and generalized using dynamic movement primitives (DMP). Further improvement of the identification error rate is possible by choosing a different deposited sample treatment method (e.g., semi-extraction, wet deposition).
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