☆ 4.6 Article

Ferroptosis, necroptosis, and pyroptosis in the tumor microenvironment: Perspectives for immunotherapy of SCLC

SEMINARS IN CANCER BIOLOGY (2022)

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Inhibition of kras-derived exosomes downregulates immunosuppressive BACH2/GATA-3 expression via RIP-3 dependent necroptosis and miR-146/miR-210 modulation

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Article Oncology

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CA-A CANCER JOURNAL FOR CLINICIANS (2020)

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Review Oncology

Myeloid-derived suppressor cells-new and exciting players in lung cancer

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JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)

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Gasdermin E-mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome

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SCIENCE IMMUNOLOGY (2020)

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Article Oncology

Pembrolizumab or Placebo Plus Etoposide and Platinum as First-Line Therapy for Extensive-Stage Small-Cell Lung Cancer: Randomized, Double-Blind, Phase III KEYNOTE-604 Study

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JOURNAL OF CLINICAL ONCOLOGY (2020)

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The clinicopathological and prognostic value of the pretreatment neutrophil-to-lymphocyte ratio in small cell lung cancer: A meta-analysis

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PLOS ONE (2020)

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Harnessing Natural Killer Immunity in Metastatic SCLC

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JOURNAL OF THORACIC ONCOLOGY (2020)

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Gasdermin E suppresses tumour growth by activating anti-tumour immunity

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NATURE (2020)

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A bioorthogonal system reveals antitumour immune function of pyroptosis

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NATURE (2020)

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TIMER2.0 for analysis of tumor-infiltrating immune cells

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NUCLEIC ACIDS RESEARCH (2020)

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SIRT3 increases cisplatin sensitivity of small-cell lung cancer through apoptosis

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GENE (2020)

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Review Oncology

Ferroptosis, necroptosis, and pyroptosis in anticancer immunity

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JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)

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Programming cell pyroptosis with biomimetic nanoparticles for solid tumor immunotherapy

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BIOMATERIALS (2020)

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PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis

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NATURE CELL BIOLOGY (2020)

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CD39: the potential target in small cell lung cancer

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TRANSLATIONAL LUNG CANCER RESEARCH (2020)

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Multiple modes of cell death in neuroendocrine tumors induced by artesunate

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PHYTOMEDICINE (2020)

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Pharmacotranscriptomic Analysis Reveals Novel Drugs and Gene Networks Regulating Ferroptosis in Cancer

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CANCERS (2020)

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De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors

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COMMUNICATIONS BIOLOGY (2020)

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Article Oncology

Co-administration of sulforaphane and doxorubicin attenuates breast cancer growth by preventing the accumulation of myeloid-derived suppressor cells

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CANCER LETTERS (2020)

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Letter Biochemistry & Molecular Biology

GSDME enhances Cisplatin sensitivity to regress non-small cell lung carcinoma by mediating pyroptosis to trigger antitumor immunocyte infiltration

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SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)

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Review Oncology

Turning Cold into Hot: Firing up the Tumor Microenvironment

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TRENDS IN CANCER (2020)

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Recombinant viruses delivering the necroptosis mediator MLKL induce a potent antitumor immunity in mice

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ONCOIMMUNOLOGY (2020)

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PD-L1 Predicts Poor Prognosis in Surgically Resected Limited Stage Small-Cell Lung Cancer

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CANCER MANAGEMENT AND RESEARCH (2020)

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Targeting Ferroptosis to Iron Out Cancer

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CANCER CELL (2019)

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Immune Cell Infiltration May Be a Key Determinant of Long-Term Survival in Small Cell Lung Cancer

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JOURNAL OF THORACIC ONCOLOGY (2019)

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Article Multidisciplinary Sciences

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

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NATURE (2019)

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Review Oncology

The Tumor Microenvironment Innately Modulates Cancer Progression

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CANCER RESEARCH (2019)

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Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity

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SCIENCE IMMUNOLOGY (2019)

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Review Biochemistry & Molecular Biology

The role of pyroptosis in gastrointestinal cancer and immune responses to intestinal microbial infection

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BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2019)

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GSDMD is required for effector CD8+ T cell responses to lung cancer cells

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INTERNATIONAL IMMUNOPHARMACOLOGY (2019)

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Combination Treatment of the Oral CHK1 Inhibitor, SRA737, and Low-Dose Gemcitabine Enhances the Effect of Programmed Death Ligand 1 Blockade by Modulating the Immune Microenvironment in SCLC

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Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11

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CANCER DISCOVERY (2019)

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Article Medicine, General & Internal

Durvalumab plus platinum-etoposide versus platinum-etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial

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Epigenetics-Based Tumor Cells Pyroptosis for Enhancing the Immunological Effect of Chemotherapeutic Nanocarriers

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The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

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Randomized-controlled phase II trial of salvage chemotherapy after immunization with a TP53-transfected dendritic cell-based vaccine (Ad.p53-DC) in patients with recurrent small cell lung cancer

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Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

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Mouse lung fibroblasts are highly susceptible to necroptosis in a reactive oxygen species-dependent manner

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NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model

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CANCER RESEARCH (2018)

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Review Biochemistry & Molecular Biology

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

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The role of immune microenvironment in small-cell lung cancer: Distribution of PD-L1 expression and prognostic role of FOXP3-positive tumour infiltrating lymphocytes

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First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer

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NEW ENGLAND JOURNAL OF MEDICINE (2018)

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Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance

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CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2018)

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Molecular Targeted Therapies Elicit Concurrent Apoptotic and GSDME-Dependent Pyroptotic Tumor Cell Death

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The cell-cell interaction between tumor-associated macrophages and small cell lung cancer cells is involved in tumor progression via STAT3 activation

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Review Oncology

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CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer

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Article Oncology

Tumor infiltrating lymphocytes and PD-L1 expression in brain metastases of small cell lung cancer (SCLC)

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JOURNAL OF NEURO-ONCOLOGY (2016)

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Review Oncology

Non-canonical programmed cell death mechanisms triggered by natural compounds

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SEMINARS IN CANCER BIOLOGY (2016)

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Increased circulating CD14(+) HLA-DR-/low myeloid-derived suppressor cells are associated with poor prognosis in patients with small-cell lung cancer

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CANCER BIOMARKERS (2015)

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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

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NATURE (2015)

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Comprehensive genomic profiles of small cell lung cancer

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Ferroptosis as a p53-mediated activity during tumour suppression

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NATURE (2015)

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Robust enumeration of cell subsets from tissue expression profiles

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RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8+ T cells

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Regulation of Ferroptotic Cancer Cell Death by GPX4

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CELL (2014)

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Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

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NATURE CELL BIOLOGY (2014)

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Therapeutic regulation of myeloid-derived suppressor cells and immune response to cancer vaccine in patients with extensive stage small cell lung cancer

Cristina Iclozan et al.

CANCER IMMUNOLOGY IMMUNOTHERAPY (2013)

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The x c - cystine/glutamate antiporter as a potential therapeutic target for small-cell lung cancer: use of sulfasalazine

Jun Guan et al.

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Increased numbers of spontaneous SCLC metastasis in absence of NK cells after subcutaneous inoculation of different SCLC cell lines into pfp/rag2 double knock out mice

Stephan Sodeur et al.

CANCER LETTERS (2009)

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The IASLC Lung Cancer Staging Project Proposals Regarding the Relevance of TNM in the Pathologic Staging of Small Cell Lung Cancer in the Forthcoming (Seventh) Edition of the TNM Classification for Lung Cancer

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Reciprocal CD4+ T-Cell Balance of Effector CD62Llow CD4+ and CD62Lhigh CD25+ CD4+ Regulatory T Cells in Small Cell Lung Cancer Reflects Disease Stage

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CLINICAL CANCER RESEARCH (2008)

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Transferrin overcomes drug resistance to artemisinin in human small-cell lung carcinoma cells

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CANCER LETTERS (2002)

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