4.7 Review

Biomedical polymers: synthesis, properties, and applications

期刊

SCIENCE CHINA-CHEMISTRY
卷 65, 期 6, 页码 1010-1075

出版社

SCIENCE PRESS
DOI: 10.1007/s11426-022-1243-5

关键词

biomedical polymer; nanomedicine; cancer therapy; drug delivery; bioimaging and biosensing; tissue engineering; regenerative medicine; cytotoxicity; biocompatibility

资金

  1. National Natural Science Foundation of China [52073218, 22135005, 51873162, 51933006, 51988102, 52122310, 22075050, 51833008, 51733006, 51733001, 52122304]
  2. Jiangsu Province Science Foundation for Youths [BK20200241]
  3. Science and Technology Commission of Shanghai Municipality [20JC1414902, 21511104900]
  4. Shanghai Municipal Education Commission [2017-01-07-00-07-E00062]
  5. National Key Research and Development Program of China [2021YFA1201200]
  6. Zhejiang Provincial Key Research and Development Program [2020C01123]

向作者/读者索取更多资源

This review summarizes the recent advances in the synthesis and application of biomedical polymers, discussing their property-function relationship for corresponding biomedical applications. It highlights emerging bioactive polymers as potential biomaterials for cancer precision therapy. The challenges and outlook for the development of more efficient, healthier, and safer biomedical polymers are also discussed.
Biomedical polymers have been extensively developed for promising applications in a lot of biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis, biosensing, regenerative medicine, and disease treatment. In this review, we summarize the most recent advances in the synthesis and application of biomedical polymers, and discuss the comprehensive understanding of their property-function relationship for corresponding biomedical applications. In particular, a few burgeoning bioactive polymers, such as peptide/biomembrane/microorganism/cell-based biomedical polymers, are also introduced and highlighted as the emerging biomaterials for cancer precision therapy. Furthermore, the foreseeable challenges and outlook of the development of more efficient, healthier and safer biomedical polymers are discussed. We wish this systemic and comprehensive review on highlighting frontier progress of biomedical polymers could inspire and promote new breakthrough in fundamental research and clinical translation.

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