Intermolecular Interactions between Chlorpheniramine with 1-Butanol, 1-Pentanol, and 1-Hexanol

Density (rho), viscosity (eta), and ultrasonic velocity ( U) are studied for binary liquid mixtures of chlorpheniramine with 1-butanol, 1-pentanol, and 1-hexanol at 303 K. Adiabatic compressibility (beta), free length (L-f), free volume (V-f), internal pressure (pi i), viscous relaxation time (tau), and Gibbs free energy (Delta G) are calculated by using the experimental data. The excess values of the above parameters (beta(E) , L-f(E) , V-F(E), pi(E)(i) , tau(E), and Delta G(E)) from their ideal values are also determined and fitted with Redlich-Kister polynomial equation. The changes in the determined parameters are interpreted in terms of the intermolecular interaction between the liquid mixtures. The significant changes in the ideal parameters and the excess parameters have confirmed the existence of the intermolecular interactions between the selected liquid system. From the observations, strength of intermolecular interaction of chlorpheniramine with the selected alcohols is in the order of 1-butanol < 1-pentanol < 1 -hexanol.

Automated summary

The physical properties of binary mixtures of chlorpheniramine with different alcohols were studied. Various parameters were calculated based on experimental data, and the strength of intermolecular interactions was determined by comparing ideal values and excess values.