期刊
JOURNAL OF APPLIED PHYSIOLOGY
卷 120, 期 6, 页码 674-682出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/japplphysiol.00625.2015
关键词
aging; hypertrophy; muscle protein; protein turnover
资金
- NIH [DK-94483, DK-56341, UL1 TR-000448, TR-000450]
Skeletal muscle is the major constituent of lean body mass and essential for the body's locomotor function. Women have less muscle mass (and more body fat) than men and are therefore not able to exert the same absolute maximal force as men. The difference in body composition between the sexes is evident from infancy but becomes most marked after puberty (when boys experience an accelerated growth spurt) and persists into old age. During early adulthood until approximately the fourth decade of life, muscle mass is relatively stable, both in men and women, but then begins to decline, and the rate of loss is slower in women than in men. In this review we discuss the underlying mechanisms responsible for the age-associated sexual dimorphism in muscle mass (as far as they have been elucidated to date) and highlight areas that require more research to advance our understanding of the control of muscle mass throughout life.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据