相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Acquired temozolomide resistance in MGMTlow gliomas is associated with regulation of homologous recombination repair by ROCK2
Xin Zhang et al.
CELL DEATH & DISEASE (2022)
Molecular Mechanisms of Treatment Resistance in Glioblastoma
Alexander Ou et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Analysis of clonogenic growth in vitro
Nikko Brix et al.
NATURE PROTOCOLS (2021)
Current status and recent advances in reirradiation of glioblastoma
Giuseppe Minniti et al.
RADIATION ONCOLOGY (2021)
Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma
Ulrike Schoetz et al.
CELL DEATH & DISEASE (2021)
Target-Based Radiosensitization Strategies: Concepts and Companion Animal Model Outlook
Matthew R. Berry et al.
Frontiers in Oncology (2021)
Inhibition of HSP90 as a Strategy to Radiosensitize Glioblastoma: Targeting the DNA Damage Response and Beyond
Michael Orth et al.
FRONTIERS IN ONCOLOGY (2021)
Molecular Mechanisms of Drug Resistance in Glioblastoma
Maya A. Dymova et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Cellular functions of the protein kinase ATM and their relevance to human disease
Ji-Hoon Lee et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)
DNA damage repair in glioblastoma: current perspectives on its role in tumour progression, treatment resistance and PIKKing potential therapeutic targets
Mathew Lozinski et al.
CELLULAR ONCOLOGY (2021)
Conducting correlation analysis: important limitations and pitfalls
Roemer J. Janse et al.
CLINICAL KIDNEY JOURNAL (2021)
Management of glioblastoma: State of the art and future directions
Aaron C. Tan et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2020)
A Brain-Penetrating Hsp90 Inhibitor NXD30001 Inhibits Glioblastoma as a Monotherapy or in Combination With Radiation
Hao Chen et al.
FRONTIERS IN PHARMACOLOGY (2020)
Targeting the DNA Damage Response to Overcome Cancer Drug Resistance in Glioblastoma
Alessandra Ferri et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Sustained inhibition of PARP-1 activity delays glioblastoma recurrence by enhancing radiation-induced senescence
Atanu Ghorai et al.
CANCER LETTERS (2020)
PARP Inhibitors: Clinical Relevance, Mechanisms of Action and Tumor Resistance
Maddison Rose et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
p53: 800 million years of evolution and 40 years of discovery
Arnold J. Levine
NATURE REVIEWS CANCER (2020)
DNA damage response signaling pathways and targets for radiotherapy sensitization in cancer
Rui-Xue Huang et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
Ataxia telangiectasia and Rad3-related inhibitors and cancer therapy: where we stand
Lin Mei et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
The Multifaceted p21 (Cip1/Waf1/CDKN1A) in Cell Differentiation, Migration and Cancer Therapy
Nina-Naomi Kreis et al.
CANCERS (2019)
ATR kinase inhibitors NVP-BEZ235 and AZD6738 effectively penetrate the brain after systemic administration
Guido Frosina et al.
RADIATION ONCOLOGY (2018)
Radiosensitization Effect of Talazoparib, a Parp Inhibitor, on Glioblastoma Stem Cells Exposed to Low and High Linear Energy Transfer Radiation
Paul Lesueur et al.
SCIENTIFIC REPORTS (2018)
MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors
Marialaura Petroni et al.
CELL DEATH & DISEASE (2018)
Discovery and Characterization of AZD6738, a Potent Inhibitor of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Kinase with Application as an Anticancer Agent
Kevin M. Foote et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Overcoming therapeutic resistance in glioblastoma: the way forward
Satoru Osuka et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Non-homologous DNA end joining and alternative pathways to double-strand break repair
Howard H. Y. Chang et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor
Timothy R. L. Howes et al.
DNA REPAIR (2017)
Efficacy of Onalespib, a Long-Acting Second-Generation HSP90 Inhibitor, as a Single Agent and in Combination with Temozolomide against Malignant Gliomas
Alessandro Canella et al.
CLINICAL CANCER RESEARCH (2017)
Therapeutic options in recurrent glioblastoma-An update
Katharina Seystahl et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2016)
DNA repair mechanisms and their clinical impact in glioblastoma
Helene Erasimus et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2016)
On the analysis of clonogenic survival data: Statistical alternatives to the linear-quadratic model
Steffen Unkel et al.
RADIATION ONCOLOGY (2016)
HSP90 inhibition as a means of radiosensitizing resistant, aggressive soft tissue sarcomas
Anne Ernst et al.
CANCER LETTERS (2015)
Selective Inhibition of Parallel DNA Damage Response Pathways Optimizes Radiosensitization of Glioblastoma Stem-like Cells
Shafiq U. Ahmed et al.
CANCER RESEARCH (2015)
DNA repair mechanisms in cancer development and therapy
Alessandro Torgovnick et al.
FRONTIERS IN GENETICS (2015)
53BP1 foci as a marker of tumor cell radiosensitivity
E. Markova et al.
NEOPLASMA (2015)
Contribution of ATM and ATR to the Resistance of Glioblastoma and Malignant Melanoma Cells to the Methylating Anticancer Drug Temozolomide
Marcus Eich et al.
MOLECULAR CANCER THERAPEUTICS (2013)
ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells
Aditi Nadkarni et al.
JOURNAL OF NEURO-ONCOLOGY (2012)
The DNA damage response and cancer therapy
Christopher J. Lord et al.
NATURE (2012)
Drug Resistance in Glioblastoma: A Mini Review
Catherine P. Haar et al.
NEUROCHEMICAL RESEARCH (2012)
The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance
Peter Bouwman et al.
NATURE REVIEWS CANCER (2012)
Epigenetic changes of DNA repair genes in cancer
Christoph Lahtz et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2011)
The MRN complex in double-strand break repair and telomere maintenance
Brandon J. Lamarche et al.
FEBS LETTERS (2010)
γH2AX: a sensitive molecular marker of DNA damage and repair
L-J Mah et al.
LEUKEMIA (2010)
Molecular Targets for Tumor Radiosensitization
Philip J. Tofilon et al.
CHEMICAL REVIEWS (2009)
Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion
Sarah E. Golding et al.
MOLECULAR CANCER THERAPEUTICS (2009)
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
Roger Stupp et al.
LANCET ONCOLOGY (2009)
The DNA-damage response in human biology and disease
Stephen P. Jackson et al.
NATURE (2009)
Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair
Xi Chen et al.
CANCER RESEARCH (2008)
Epidemiology of brain tumors
James L. Fisher et al.
NEUROLOGIC CLINICS (2007)
Inhibition of Hsp90 compromises the DNA damage response to radiation
Hideaki Dote et al.
CANCER RESEARCH (2006)
MGMT gene silencing and benefit from temozolomide in glioblastoma
ME Hegi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
R Stupp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
分享论文
