4.5 Article

Dorsolateral prefrontal cortex mediates working memory processes in motor skill learning

期刊

PSYCHOLOGY OF SPORT AND EXERCISE
卷 59, 期 -, 页码 -

出版社

ELSEVIER
DOI: 10.1016/j.psychsport.2021.102129

关键词

Dorsolateral prefrontal cortex; Repetitive transcranial magnetic stimulation; Motor skill learning; Working memory

资金

  1. National Natural Science Foundation of China [11932013, 31971024]
  2. Natural Science Foundation of Shanghai [19ZR1453000]
  3. Outstanding Clinical Discipline Project of Shanghai Pudong [PWYgy2018-04]

向作者/读者索取更多资源

This study provides empirical evidence for the importance of the left DLPFC in the working memory manipulation during motor skill learning.
Neuroimaging studies have shown that the dorsolateral prefrontal cortex (DLPFC) is recruited during motor skill learning, which suggests the involvement of the DLPFC in working memory (WM) processes, such as selection and integration of motor representations temporarily stored in WM. However, direct evidence linking activation of the DLPFC to WM storage and manipulation during motor skill learning in real-time is rare. In this study, we conducted two experiments to investigate the causal role of DLPFC activity in WM storage and manipulation during motor skill learning under low and high WM-demand conditions. Participants received continuous theta burst stimulation (cTBS) and sham stimulation (crossover design) over the left DLPFC (experiment 1) or right DLPFC (experiment 2). Before and after stimulation, participants in both experiments performed a sequential finger-tapping (SFT) task containing repeated sequence (low-WM demand) and non-repeated sequence (highWM demand) conditions which are used to study WM processes. The number of correct sequences (NoCS) and reproduction error rate were analyzed. Learning gains in NoCS improved significantly with the practice for both sequence types in the presence of either stimulation type. Compared to sham stimulation, cTBS over the left DLPFC resulted in significantly reduced learning gains in NoCS for non-repeated sequences. These results suggest that the left DLPFC contributes to WM manipulation during motor skill learning.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.5
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据