期刊
JOURNAL OF APPLIED PHYSICS
卷 119, 期 8, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.4942618
关键词
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资金
- U.S. DoE, Office of Basic Energy Sciences [DE FG02 07ER46438]
- Basque Government
- Bizkaia Talent Program from Basque Country
- NIH [R15GM117531]
- National Program for the Promotion of Human Resources within the National Plan of Scientific Research, Development and Innovation, Ministerio de Economia y Competitividad Vasco/Eusko Jaurlaritza, Direccion de Politica Cientifica
A multifunctional nanocomposite formed by superparamagnetic maghemite nanoparticles of 12.8 +/- 61.7 nm diameter encapsulated in lipid unilamellar vesicles (i.e., magnetoliposomes) was prepared using size exclusion chromatography (SEC). The quality of the synthesized nanoparticles was characterized by transmission electron microscopy and X-ray diffraction measurements. Using a modified Langevin model, we analyzed the magnetic measurement data. We found that the SEC prepared magnetoliposomes possess superparamagnetic characteristics. We also performed calorimetric based magnetic hyperthermia measurement to quantify field dependent heating efficiency of the obtained magnetoliposomes. A heating efficiency of similar to 160 W/g at 800 Oe and 310 kHz was obtained. Finally, we used magnetoreactance-based biodetection to explore the effect of magnetoliposomes on magneto-impedance (MI) and magneto-reactance (MX) ratios. Compared to pure vesicles, magnetoliposomes were found to increase the MI and MX ratios by similar to 1.0% and 4.5%, respectively. Together, our magnetic hyperthermia and magneto-detection measurements indicate that our SEC prepared magnetoliposomes exhibit good qualities for hyperthermia and biosensing applications. (C) 2016 AIP Publishing LLC.
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