Evaluation of the extraction process parameters on bioactive compounds of cinnamon bark: A comparative study

In recent times, there has been special attention to the antidiabetic properties of herbal medicine like cinnamon, because of its major compounds such as cinnamic acid and cinnamaldehyde. This study optimizes an effective technique for the extraction of cinnamic acid and cinnamaldehyde from cinnamon bark. The effective parameters of both microwave and ultrasound methods were considered and then compared with the soxhlet extraction method. The impact of different solvent types, temperature and process time, solid: solvent portion, particle size, on the yield of cinnamic acid and cinnamaldehyde extraction were investigated. In addition, all the obtained extraction samples were analyzed by the newly developed HPLC method via UV detector. Finally, the optimized extraction factors were obtained 85 % aqueous ethanol; solid: solvent portion, 1:40 g/mL; particle size of 0.18 mm; for both microwave and ultrasound extraction methods. The maximum yield of cinnamic acid and cinnamaldehyde in microwave extraction were gained 3.9 and 49.4 mg/g, respectively. Both advanced extraction techniques with our obtained optimized conditions are suggested for cinnamon bark.

Automated summary

This study optimized the extraction of cinnamic acid and cinnamaldehyde from cinnamon bark, investigating the impact of different solvent types, temperature, process time, solid: solvent portion, and particle size on the yield. The obtained extraction samples were analyzed by HPLC with a UV detector.