4.5 Article

Improvement in fatique and sleep measures with the dual orexin receptor antagonist lemborexant in adults with insomnia disorder

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Clinical Neurology

Progression of fatigue in Parkinson's disease - a 9-year follow-up

S. O. Ongre et al.

Summary: The study found a significant increase in fatigue symptoms among PD patients during the first 9 years after diagnosis, with a large proportion experiencing significant changes in fatigue scores between consecutive visits. Factors such as female gender, comorbidity at baseline, depressive symptoms, dependency in activities of daily living, and better cognitive functioning were significantly associated with higher levels of fatigue, while the use of dopamine agonists was linked to lower levels of fatigue.

EUROPEAN JOURNAL OF NEUROLOGY (2021)

Article Allergy

Fatigue Is Common and Predicted by Female Gender and Sleep Disturbance in Patients with Chronic Spontaneous Urticaria

Kemal Erol et al.

Summary: Based on a study of 103 CSU patients and 35 healthy control subjects, it was found that fatigue is a common and important symptom in CSU patients, negatively affecting their quality of life. Female patients and those with sleep disturbances are more likely to experience fatigue symptoms.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2021)

Article Clinical Neurology

Safety and efficacy of amantadine, modafinil, and methylphenidate for fatigue in multiple sclerosis: a randomised, placebo-controlled, crossover, double-blind trial

Bardia Nourbakhsh et al.

Summary: The study compared the efficacy of amantadine, modafinil, and methylphenidate in alleviating fatigue in multiple sclerosis patients. Results showed that none of the medications were superior to placebo in improving fatigue and had more frequent adverse events.

LANCET NEUROLOGY (2021)

Article Orthopedics

Minimal Clinically Important Differences for Measures of Pain, Lung Function, Fatigue, and Functionality in Spinal Cord Injury

Margarida Sobreira et al.

Summary: The study aimed to determine MCIDs for various outcome measures in SCI patients after rehabilitation, which can help health professionals interpret results and guide interventions effectively.

PHYSICAL THERAPY (2021)

Article Gastroenterology & Hepatology

Fatigue in inflammatory bowel disease and its impact on daily activities

Philipp Schreiner et al.

Summary: Fatigue is more prevalent and severe in patients with IBD compared to the general population, with associations found with female gender, age at diagnosis, disease duration, nocturnal diarrhea, low education level, and symptoms of depression and anxiety.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2021)

Article Geriatrics & Gerontology

IMPACT OF LEMBOREXANT ON INSOMNIA DISEASE SEVERITY AND FATIGUE IN ELDERLY SUBJECTS WITH INSOMNIA FROM SUNRISE-2

Jane Yardley et al.

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2020)

Review Immunology

Fatigue, Sleep, and Autoimmune and Related Disorders

Mark R. Zielinski et al.

FRONTIERS IN IMMUNOLOGY (2019)

Article Psychiatry

Factors associated with fatigue in patients with insomnia

Seog Ju Kim et al.

JOURNAL OF PSYCHIATRIC RESEARCH (2019)

Review Clinical Neurology

Insomnia in the Elderly: A Review

Dhaval Patel et al.

JOURNAL OF CLINICAL SLEEP MEDICINE (2018)

Review Neurosciences

The Orexin/Receptor System: Molecular Mechanism and Therapeutic Potential for Neurological Diseases

Chunmei Wang et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)

Article Pharmacology & Pharmacy

In Vitro and In Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist

Carsten Theodor Beuckmann et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2017)

Article Clinical Neurology

Fatigue as a symptom or comorbidity of neurological diseases

Iris-Katharina Penner et al.

Nature Reviews Neurology (2017)

Article Behavioral Sciences

Validity and reliability of the Fatigue Severity Scale in Finnish multiple sclerosis patients

Eija Rosti-Otajarvi et al.

BRAIN AND BEHAVIOR (2017)

Article Chemistry, Medicinal

Orexin Receptor Antagonists: New Therapeutic Agents for the Treatment of Insomnia

Anthony J. Roecker et al.

JOURNAL OF MEDICINAL CHEMISTRY (2016)

Review Clinical Neurology

Fatigue and depression in multiple sclerosis: pharmacological and non-pharmacological interventions

P. Brenner et al.

ACTA NEUROLOGICA SCANDINAVICA (2016)

Review Health Care Sciences & Services

Minimal important differences for fatigue patient reported outcome measures-a systematic review

Asa Nordin et al.

BMC MEDICAL RESEARCH METHODOLOGY (2016)

Review Clinical Neurology

Hypothalamic Dysfunction and Multiple Sclerosis: Implications for Fatigue and Weight Dysregulation

Kevin G. Burfeind et al.

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2016)

Review Pharmacology & Pharmacy

Emerging role of orexin antagonists in insomnia therapeutics: An update on SORAs and DORAs

Anil Kumar et al.

PHARMACOLOGICAL REPORTS (2016)

Review Clinical Neurology

The neurobiology, investigation, and treatment of chronic insomnia

Dieter Riemann et al.

LANCET NEUROLOGY (2015)

Article Medicine, General & Internal

Cognitive Behavioral Therapy for Insomnia Comorbid With Psychiatric and Medical Conditions A Meta-analysis

Jade Q. Wu et al.

JAMA INTERNAL MEDICINE (2015)

Review Pharmacology & Pharmacy

Discovery and development of orexin receptor antagonists as therapeutics for insomnia

C. J. Winrow et al.

BRITISH JOURNAL OF PHARMACOLOGY (2014)

Article Clinical Neurology

Reward responsiveness and fatigue in multiple sclerosis

Matteo Pardini et al.

MULTIPLE SCLEROSIS JOURNAL (2013)

Article Pharmacology & Pharmacy

Orexin/Hypocretin: A Neuropeptide at the Interface of Sleep, Energy Homeostasis, and Reward System

N. Tsujino et al.

PHARMACOLOGICAL REVIEWS (2009)

Article Health Care Sciences & Services

Determination of the minimal clinically important difference for seven fatigue measures in rheumatoid arthritis

Jacques Pouchot et al.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2008)

Article Clinical Neurology

Validation of the Fatigue Severity Scale in a Swiss Cohort

Philipp O. Valko et al.

Article Biochemistry & Molecular Biology

Promotion of sleep by targeting the orexin system in rats, dogs and humans

Catherine Brisbare-Roch et al.

NATURE MEDICINE (2007)

Article Psychiatry

Functional neuroimaging evidence for hyperarousal in insomnia

EA Nofzinger et al.

AMERICAN JOURNAL OF PSYCHIATRY (2004)

Review Clinical Neurology

Insomnia and daytime functioning

BW Riedel et al.

SLEEP MEDICINE REVIEWS (2000)