4.8 Article

Overexpression of pea α-carboxyltransferase in Arabidopsis and camelina increases fatty acid synthesis leading to improved seed oil content

期刊

PLANT JOURNAL
卷 110, 期 4, 页码 1035-1046

出版社

WILEY
DOI: 10.1111/tpj.15721

关键词

acetyl-CoA carboxylase (ACCase); absolute protein quantification; subunit stoichiometry; fatty acid biosynthesis; rational metabolic engineering; alpha-carboxyltransferase; Camelina sativa

资金

  1. National Science Foundation [IOS-1339385, PGRP-IOS-1829365]
  2. United States Department of Agriculture National Institute of Food and Agriculture multi-state project [NC1203]
  3. Food for the 21st Century program at University of Missouri

向作者/读者索取更多资源

The limiting subunit of plant acetyl-CoA carboxylase, identified as alpha-carboxyltransferase, was found to be responsible for the increase in both fatty acid synthesis rate and seed oil content when overexpressed in Arabidopsis and Camelina.
The limiting subunit of plant acetyl-CoA carboxylase was identified as alpha-carboxyltransferase via absolute protein quantification; overexpression of this subunit in Arabidopsis and Camelina led to an increase of both fatty acid synthesis rate and seed oil content.

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