4.7 Article

Discovery of the directionally detoxification effect and chemical mechanism of Ginseng-Fuzi co-decoction based on real-time online filtration electrospray ionization mass spectrometry

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemical Research Methods

The global profiling of alkaloids in Aconitum stapfianum and analysis of detoxification material basis against Fuzi

Sisi Liu et al.

Summary: Aconitum alkaloids are versatile and challenging to rapidly identify, especially positional isomers. This study successfully characterized 124 alkaloids in A. stapfianum and identified 25 characteristic markers, with 14 compounds specific to A. stapfianum.

JOURNAL OF CHROMATOGRAPHY A (2021)

Article Plant Sciences

Online discovery of the molecular mechanism for directionally detoxification of Fuzi using real-time extractive electrospray ionization mass spectrometry

Zi-Dong Qiu et al.

Summary: This study aimed to develop a complete molecular mechanism exploration strategy in the complex medicinal herb decocting system, clarifying the internal molecular mechanism of processing detoxification on Aconitum, and exploring valid approaches for detoxification. By using an advanced online real-time platform, the study successfully characterized components in the complex Aconitum decocting system, discovered that fat meat could detoxify Aconitum directionally while preserving therapeutic effects, and proposed a novel reaction pathway based on nucleophilic substitution mechanism.

JOURNAL OF ETHNOPHARMACOLOGY (2021)

Article Biochemical Research Methods

A mass spectrometry database for identification of saponins in plants

Feng-Qing Huang et al.

JOURNAL OF CHROMATOGRAPHY A (2020)

Review Plant Sciences

Ginseng in Traditional Herbal Prescriptions

Ho Jae Park et al.

JOURNAL OF GINSENG RESEARCH (2012)