期刊
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
卷 97, 期 -, 页码 50-58出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.ejmp.2022.03.016
关键词
Anthropomorphic computational breast models; Mammography; DBT; BCT; Dosimetry
资金
- Italian National Institute for Nuclear Physics (INFN) [AGATA_GR5]
- projcet MC-INFN
This study evaluated the bias introduced by homogeneous breast models in digital breast tomosynthesis (DBT) in estimating the mean glandular dose (MGD). The study also examined the glandular dose distributions in 2D and 3D x-ray breast imaging using breast models with realistic glandular tissue distribution and organ silhouette. The results showed that conventional conversion coefficients based on homogeneous breast models overestimate MGD in DBT, and the standard deviation of the glandular dose distribution is lower in breast dedicated CT (BCT) compared to digital mammography (DM) and DBT.
Purpose: To evaluate the bias to the mean glandular dose (MGD) estimates introduced by the homogeneous breast models in digital breast tomosynthesis (DBT) and to have an insight into the glandular dose distributions in 2D (digital mammography, DM) and 3D (DBT and breast dedicated CT, BCT) x-ray breast imaging by employing breast models with realistic glandular tissue distribution and organ silhouette. Methods: A Monte Carlo software for DM, DBT and BCT simulations was adopted for the evaluation of glandular dose distribution in 60 computational anthropomorphic phantoms. These computational phantoms were derived from 3D breast images acquired via a clinical BCT scanner. Results: g.c.s.T conversion coefficients based on homogeneous breast model led to a MGD overestimate of 18% in DBT when compared to MGD estimated via anthropomorphic phantoms; this overestimate increased up to 21% for recently computed DgN(DBT) conversion coefficients. The standard deviation of the glandular dose distribution in BCT resulted 60% lower than in DM and 55% lower than in DBT. The glandular dose peak - evaluated as the average value over the 5% of the gland receiving the highest dose - is 2.8 times the MGD in DM, this factor reducing to 2.6 and 1.6 in DBT and BCT, respectively. Conclusions: Conventional conversion coefficients for MGD estimates based on homogeneous breast models overestimate MGD by 18%, when compared to MGD estimated via anthropomorphic phantoms. The ratio be-tween the peak glandular dose and the MGD is 2.8 in DM. This ratio is 8% and 75% higher than in DBT and BCT, respectively.
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