Intussusception and COVID-19 in Infants: Evidence for an Etiopathologic Correlation

Nonrespiratory conditions related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have been largely described. Ileocolic intussusception has been reported in association with SARS-CoV-2 infection in 10 children, raising the possibility of an etiopathologic role for the virus, but none of these cases documented tissue pathology that would have supported SARS-CoV-2 intestinal inflammation. We report 2 cases of intussusception in patients with SARS-CoV-2 infection who were treated at different pediatric tertiary centers in Europe and provide evidence of the presence of the virus in mesenteric and intestinal tissues of the patients.

Automated summary

This article reports two cases of intussusception in patients with SARS-CoV-2 infection and provides evidence of the presence of the virus in mesenteric and intestinal tissues of the patients.