期刊
PEDIATRIC ALLERGY AND IMMUNOLOGY
卷 33, 期 2, 页码 -出版社
WILEY
DOI: 10.1111/pai.13738
关键词
allergic rhinitis; children; early diagnosis; health survey; questionnaire
资金
- Beijing Hospitals Authority' Ascent Plan [DFL20191201]
- Special Fund of The Pediatric Medical Coordinated Development Center of Beijing Municipal Administration of Hospitals [XTZD20180103]
- Respiratory Research Project of National Clinical Research Center for Respiratory Diseases [HXZX-20210501]
This study developed a questionnaire for screening allergic rhinitis in children aged 3 years and younger, and assessed its accuracy and reliability. The questionnaire was distributed through an online community and evaluated for internal consistency, content validity, criterion-related validity, and diagnostic accuracy.
Background There are a limited number of validated questionnaires available for use in the clinical screening for allergic rhinitis (AR) in children <= 3 years old. We developed a novel self-reported questionnaire and assessed its accuracy and reliability. Methods After establishing a pool of items, which were screened by experts, the Young Children Allergic Rhinitis Questionnaire (YCAR-Q) was administered to a birth cohort in the Shunyi District (Beijing, China). The electronic version of the YCAR-Q was distributed through the online community. Children were invited to visit a physician for examination. The diagnostic criteria included symptoms, physical examination findings, and specific serum immunoglobulin E tests. Each item on the questionnaire was evaluated, and the questionnaire's internal consistency, content validity, criterion-related validity, and diagnostic accuracy were assessed. Results The six-item YCAR-Q was distributed to 7423 parents, and 3037 valid questionnaires were recovered. In total, 1521 children visited a physician for examination, of which 82 were found to have AR. In terms of internal consistency, Cronbach's coefficient was 0.777 and all six questionnaire items were retained. The average scale-level content validity index value was 1. The area under the curve was 0.759. The total scores ranged from 0 to 6, and the cutoff value for diagnosing AR was 3, with a sensitivity of 68.29% and a specificity of 76.58%. Conclusions This cross-sectional study indicated that the YCAR-Q could detect AR in children <= 3 years old. This brief and simple test may be used effectively in clinical practice.
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