4.3 Review

Carbon Dots from Natural Sources for Biomedical Applications

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Carbon-Based Materials in Photodynamic and Photothermal Therapies Applied to Tumor Destruction

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Summary: Carbon-based materials show promise in cancer treatment, with potential applications in photodynamic and photothermal therapies for various types of tumors.

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Summary: In this study, carbon nanodots (CNDs) were synthesized using grass as a carbon source and characterized by various techniques. The grass-derived CNDs exhibited strong absorption and fluorescence emission, and showed excellent sensitivity and selectivity for the detection of Cu2+ ions.

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A multifunctional chemical toolbox to engineer carbon dots for biomedical and energy applications

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Amine functionalized carbon quantum dots from paper precursors for selective binding and fluorescent labelling applications

Varsha Lisa John et al.

Summary: This study reports a novel synthesis route for preparing carbon quantum dots (CQDs) with customized surface functionality. By chemically modifying paper precursors and tethering amine groups on the paper substrates, CQDs with amine functional groups on the surface can be synthesized. The amine functionalization on the surface of CQDs enables their applications in DNA binding, suggesting their potential as efficient biological probes.

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Green synthesis of multifunctional carbon quantum dots: An approach in cancer theranostics

Jalaja Prasad Malavika et al.

Summary: Carbon quantum dots (CQDs) have attracted significant attention due to their unique characteristics and potential applications in diverse biomedical fields. This review comprehensively examines the different synthesis methods and raw materials used in recent years, and focuses on the potential application of CQDs in cancer theranostics, particularly in bio-imaging and targeted drug delivery.

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Carbon quantum dots prepared from onion extract as fluorescence turn-on probes for selective estimation of Zn2+ in blood plasma

Debabrata Ghosh Dastidar et al.

Summary: Zinc is an essential micronutrient with roles in numerous biological processes, but deficiency or excess can lead to diseases. Carbon quantum dots have been developed for sensing Zn2+ ions in plasma, showing high sensitivity and potential for early disease detection.

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Sustainable synthesis of carbon dots from agarose waste and prospective application in sensing of L-aspartic acid

Pooja Chauhan et al.

Summary: The successful synthesis of carbon dots (CDs) through one-step thermal treatment has resulted in CDs with high quantum yield and outstanding luminescent and physicochemical properties, suitable for biological component recognition. The developed CDs exhibit extraordinary sensitivity and selectivity towards i-aspartic acid, with potential for real sample recognition and a high recovery rate.

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Biomass-Based Carbon Dots: Current Development and Future Perspectives

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Summary: Carbon dots are regarded as a solution to the challenges faced by semiconductor quantum dots due to their high biocompatibility and ability to be synthesized from abundant and non-toxic biomass materials. In the biomedical field, biomass-based carbon dots hold great potential for research, especially in terms of synthesis and application, showing promising future development prospects.

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Summary: This study reports a sand bath assisted strategy for synthesizing fluorescent carbon dots (CDs) using citrus fruit peels as a renewable green resource, overcoming the need for alkaline or acidic synthesis environments. The CDs showed excellent water solubility, superior optical properties, and significant free radical scavenging activity, making them promising as biological labels for cellular imaging.

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Green Synthesis of Self-Passivated Fluorescent Carbon Dots Derived from Rice Bran for Degradation of Methylene Blue and Fluorescent Ink Applications

Vinoth Kumar Jothi et al.

Summary: Natural products have been utilized as a powerful carbon source to synthesize carbon dots with interesting physical and chemical properties. A facile hydrothermal synthesis method using rice bran as a biogenic precursor was reported for preparing fluorescent carbon dots without any surface passivation agent. The synthesized RB-CDs exhibited green emission with a fluorescence quantum yield of 7.4% and were efficiently applied as a catalyst for the degradation of methylene blue dye, as well as a fluorescent ink for anti-counterfeiting applications.

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One-step synthesis of N, P Co-doped orange carbon quantum dots with novel optical properties for bio-imaging

Naixin Li et al.

Summary: In this study, nitrogen and phosphorus co-doped carbon dots were prepared using a solvothermal synthesis strategy, resulting in improved electronic properties and tunable luminescence. The prepared carbon dots showed excitation-dependent emission in the blue region and excitation-independent emission in the orange region, with a high quantum yield of 47%. The N, P-CDs were found to be non-toxic to cells and suitable for cell imaging applications, suggesting their potential as excellent bioimaging probes.

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Carbon dots from Artemisiae Argyi Folium Carbonisata: strengthening the anti-frostbite ability

Hui Kong et al.

Summary: The novel carbon dots (CDs) were discovered and separated from Artemisiae Argyi Folium Carbonisata (AAFC) aqueous extract in this study. The AAFC-CDs were characterized by various methods and showed potential for clinical applications in treating frostbite by reducing tissue damage and increasing energy supply.

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Carbon-Based Quantum Dots for Supercapacitors: Recent Advances and Future Challenges

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Summary: The translated paragraph introduces carbon-based quantum dots (C-QDs) as materials for supercapacitors, with superior optoelectronic properties and great application potential, in either bare electrode or composite form to enhance supercapacitor performances. The review also highlights the latest progress and application prospects of C-QDs in the field of supercapacitors.

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Green one-step synthesis of carbon quantum dots from orange peel for fluorescent detection of Escherichia coli in milk

Xuetao Hu et al.

Summary: Carbon quantum dots synthesized from orange peel were used as a green and efficient fluorescent probe for detecting E. coli, showing high sensitivity and reliability. The fluorescent method based on CQDs-MNPs allows for accurate analysis of contaminated milk samples, demonstrating great potential in ensuring food quality and safety.

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Sustainable synthesis of carbon quantum dots from banana peel waste using hydrothermal process for in vivo bioimaging

Raji Atchudan et al.

Summary: This study reported a sustainable synthesis of carbon quantum dots (CQDs) from banana peel waste by a simple hydrothermal method. The resulting CQDs have a narrow size distribution, exhibit intense blue fluorescence, and have high photostability, making them suitable for bioimaging applications.

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An Ultrasensitive Turn-On Ratiometric Fluorescent Probes for Detection of Ag+ Based On Carbon Dots/SiO2 and Gold Nanoclusters

Jia An et al.

Summary: Ratiometric fluorescent probes constructed in this study showed high accuracy and sensitivity for the detection of Ag+. The fluorescence color of the probes changes as the concentration of Ag+ increases. These probes have the potential to be applied in environmental monitoring and food safety assessment, with the ability for visual detection of Ag+.

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Summary: This study reported an economical, easy, greener, and non-toxic synthesis method of water-soluble carbon quantum dots (CQDs), which exhibit strong blue fluorescence under UV lamp and show a sensitive response to Fe3+ ions. TEM measurements confirmed their spherical morphology and varying sizes in the range of 0.5-5 nm, with a detection limit of 0.2 μM.

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Summary: Carbon dots have gained immense interest due to their unique features, with researchers focusing on green synthesis methods for quantum dots used in bio-sensing, cellular imaging, and drug delivery. However, there are still some mysteries surrounding potential drawbacks and limitations. Other biomedical and biotechnological applications are also being highlighted.

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Facile and High-yield Synthesis of N-doped Carbon Quantum Dots from Biomass Quinoa Saponin for the Detection of Co2+

Cuo Zhou et al.

Summary: The hydrothermal synthesis of carbon quantum dots (CQDs) from natural biomass is a green and sustainable approach for their applications. In this study, CQDs based on quinoa saponin were prepared and characterized, showing high fluorescence quantum yield and sensitivity for Co2+ detection. The CQDs were successfully used for fluorescence imaging and demonstrated low toxicity, with potential applications in metal ion detection and biosensing.

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Microwave-assisted green synthesis of fluorescent carbon quantum dots from Mexican Mint extract for Fe3+ detection and bio-imaging applications

Natarajan Architha et al.

Summary: Biomass-derived carbon quantum dots synthesized from Mexican Mint leaves via microwave-assisted reflux method exhibited strong fluorescence properties and high sensitivity to Fe3+ ions, allowing for the construction of logic gates and effective application in cell imaging.

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Summary: Precise nanomedicine has been extensively explored for effective cancer imaging and treatment, with carbon dots being a new and highly interesting member of carbon-based nanomaterials in the field of nanomedicine. This review provides concise insights into the recent development of CDs in nanomedicine research, covering preparation, functionalization processes, and key applications.

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A sustainable green synthesis of functionalized biocompatible carbon quantum dots from Aloe barbadensis Miller and its multifunctional applications

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Chlorine Modulation Fluorescent Performance of Seaweed-Derived Graphene Quantum Dots for Long-Wavelength Excitation Cell-Imaging Application

Weitao Li et al.

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Photoluminescence carbon nano dots for the conductivity based optical sensing of dopamine and bioimaging applications

Punuri Jayasekhar Babu et al.

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