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False-negative MRI biomarkers of tumour response to targeted cancer therapeutics
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Yuya Yamagishi et al.
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Ethan Cerami et al.
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Copy number increase of aurora kinase A in colorectal cancers: a correlation with tumor progression
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Carol Kilkenny et al.
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HURP is part of a ran-dependent complex involved in spindle formation
MD Koffa et al.
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K Kinoshita et al.
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Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215
QY Li et al.
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T Hirota et al.
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MJ Kallio et al.
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