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Hideharu Hashimoto et al.
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Xavier Robert et al.
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John S. Scotti et al.
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Lulu Hu et al.
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Guifang Jia et al.
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P. Emsley et al.
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xia2: an expert system for macromolecular crystallography data reduction
G. Winter
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Rasheduzzaman Chowdhury et al.
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Phaser crystallographic software
Airlie J. McCoy et al.
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B Yu et al.
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STRAP:: editor for STRuctural Alignments of Proteins
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