Effectiveness of Homologous and Heterologous Covid-19 Boosters against Omicron

Covid-19 Vaccine Boosters against Omicron Among persons vaccinated with the adenovirus-based vaccine who received a booster dose of an mRNA vaccine, protection against the omicron variant was assessed. A single booster dose of an mRNA vaccine in recipients of a single priming dose of Ad26.COV2.S provided protection close to that of a three-dose mRNA vaccine regimen.

Automated summary

The study assessed the protection against the omicron variant in individuals vaccinated with the adenovirus-based vaccine and received a booster dose of an mRNA vaccine. It was found that a single booster dose of an mRNA vaccine provided protection close to that of a three-dose mRNA vaccine regimen in recipients of the initial dose of Ad26.COV2.S.