Why stay lonely packaged in a synaptic vesicle when you can be in good company? A GABA-glutamate gathering

Neurons can release multiple neurotransmitters. Are they packaged in segregated pools of vesicles or within the same ones? In this issue of Neuron, Kim et al., 2022, examined features of GABA-glutamate co-release at basal ganglia to habenula synapses.

Automated summary

This study examines the characteristics of co-release of GABA and glutamate at synapses from basal ganglia to habenula, shedding light on the packaging and release mechanisms of multiple neurotransmitters.