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注意：仅列出部分参考文献，下载原文获取全部文献信息。Xist spatially amplifies SHARP/SPEN recruitment to balance chromosome-wide silencing and specificity to the X chromosome
Joanna W. Jachowicz et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2022)
Xist nucleates local protein gradients to propagate silencing across the X chromosome
Yolanda Markaki et al.
CELL (2021)
SPEN is required for Xist upregulation during initiation of X chromosome inactivation
Teresa Robert-Finestra et al.
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Time-resolved structured illumination microscopy reveals key principles of Xist RNA spreading
Lisa Rodermund et al.
SCIENCE (2021)
SPEN integrates transcriptional and epigenetic control of X-inactivation
Francois Dossin et al.
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A protein assembly mediates Xist localization and gene silencing
Amy Pandya-Jones et al.
NATURE (2020)
Phase separation drives X-chromosome inactivation: a hypothesis
Andrea Cerase et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2019)
lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA
Megan D. Schertzer et al.
MOLECULAR CELL (2019)
Systematic Discovery of Xist RNA Binding Proteins
Ci Chu et al.
CELL (2015)
The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3
Colleen A. McHugh et al.
NATURE (2015)
The Xist RNA-PRC2 complex at 20-nm resolution reveals a low Xist stoichiometry and suggests a hit-and-run mechanism in mouse cells
Hongjae Sunwoo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation
Anand Minajigi et al.
SCIENCE (2015)
A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing
Benoit Moindrot et al.
CELL REPORTS (2015)
Identification of Spen as a Crucial Factor for Xist Function through Forward Genetic Screening in Haploid Embryonic Stem Cells
Asun Monfort et al.
CELL REPORTS (2015)
Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy
Andrea Cerase et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci
Daniel Smeets et al.
EPIGENETICS & CHROMATIN (2014)
Chromosomal silencing and localization are mediated by different domains of Xist RNA
A Wutz et al.
NATURE GENETICS (2002)
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