4.7 Review

Functions and consequences of AID/APOBEC-mediated DNA and RNA deamination

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Genetics & Heredity

Detection of A-to-I RNA Editing in SARS-COV-2

Ernesto Picardi et al.

Summary: This study demonstrates that the A-to-G changes observed in the SARS-COV-2 genomes are genuine RNA editing events mediated by ADAR1, and these edits may have significant impact on the virus-host interactions.
Article Virology

Potential APOBEC-mediated RNA editing of the genomes of SARS-CoV-2 and other coronaviruses and its impact on their longer term evolution

Jeremy Ratcliff et al.

Summary: Members of the APOBEC family exhibit antiviral activities in mammalian cells through lethal editing of the genomes of various viruses, including RNA viruses like coronaviruses. APOBEC-like C-*U transitions are significantly overrepresented in the SARS-CoV-2 genome sequences during the COVID-19 pandemic, which may leave evolutionary imprints on coronavirus genomes. This process may lead to homoplasy and amino acid sequence changes in viral proteins, potentially explaining global depletion of C and excess of U bases in human seasonal coronavirus genomes.

VIROLOGY (2021)

Article Biochemistry & Molecular Biology

Lung expression of genes putatively involved in SARS-CoV-2 infection is modulated in cis by germline variants

Chiara E. Cotroneo et al.

Summary: Germline variants in genes involved in SARS-CoV-2 cell entry and host innate immune responses may impact susceptibility to infection. This study identified cis-eQTLs regulating the expression of 15 genes relevant to viral entry and host antiviral responses in lung tissue, suggesting a genetic basis for interindividual differences in infection risk or severity.

EUROPEAN JOURNAL OF HUMAN GENETICS (2021)

Review Biochemistry & Molecular Biology

Site-directed RNA editing: recent advances and open challenges

Hamid Mansouri Khosravi et al.

Summary: RNA editing by cytosine and adenosine deaminases changes the identity of edited bases, potentially affecting the coding potential of RNA. Nucleotide deaminases have gained attention for their recoding potential in correcting genetic mutations. RNA editing events are transient, reducing the risk of long-lasting side effects, while some RNA-based therapeutics have been FDA approved for targeting multiple cells or organs to restore genetic function.

RNA BIOLOGY (2021)

Article Multidisciplinary Sciences

Mutational signatures and heterogeneous host response revealed via large-scale characterization of SARS-CoV-2 genomic diversity

Alex Graudenzi et al.

Summary: This study conducted a large-scale analysis of intra-host genomic diversity of SARS-CoV-2, revealing interactions between host-related mutational processes and transmission dynamics, as well as identifying mutational signatures related to nucleotide substitutions. The study also demonstrated the impact of purifying selection on these mutational processes, while some mutations transition towards clonality, increasing overall genomic diversity. Additionally, phylogenomic analysis supported the hypothesis of transmission of minor variants, paving the way for integrated analysis of intra-host genomic diversity and clinical outcomes of SARS-CoV-2 infections.

ISCIENCE (2021)

Correction Biochemistry & Molecular Biology

Programmable C-to-U RNA editing using the human APOBEC3A deaminase (vol 39, e104741, 2020)

Xinxin Huang et al.

EMBO JOURNAL (2021)

Article Oncology

Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution

Subramanian Venkatesan et al.

Summary: The study reveals that APOBEC3 genes are upregulated in breast and lung preinvasive lesions, and APOBEC3B exacerbates DNA replication stress to promote cellular diversity and chromosomal instability for early selection in cancer evolution.

CANCER DISCOVERY (2021)

Article Biochemical Research Methods

Creating RNA Specific C-to-U Editase from APOBEC3A by Separation of Its Activities on DNA and RNA Substrates

Guiyue Tang et al.

Summary: The study successfully separated the dual activities of A3A and created novel human A3A variants with RNA-specific cytidine deaminase activity through the development of a reporter system and rational mutagenesis design.

ACS SYNTHETIC BIOLOGY (2021)

Article Biochemistry & Molecular Biology

Harnessing self-labeling enzymes for selective and concurrent A-to-I and C-to-U RNA base editing

Anna S. Stroppel et al.

Summary: The study demonstrates precise and efficient A-to-I RNA editing using the SNAP-ADAR tool in cell culture, and extends the platform by combining it with the HALO-tag to recruit additional effectors for optimal editing. By recruiting different deaminase activities, selective and concurrent editing of multiple RNA bases inside living cells can be achieved with moderate global off-target effects.

NUCLEIC ACIDS RESEARCH (2021)

Article Biochemistry & Molecular Biology

APOBEC1 mediated C-to-U RNA editing: target sequence and trans-acting factor contribution to 177 RNA editing events in 119 murine transcripts in vivo

Saeed Soleymanjahi et al.

Summary: This study investigates the mechanism of C-to-U RNA editing, identifying regulatory components associated with APOBEC1 targeting and analyzing sequence requirements and structure predictions. It is found that the RNA secondary structure of the editing cassette is related to editing frequency, and cofactor dominance impacts editing frequency. By developing a model, RNA editing efficiency can be predicted, enhancing understanding of editing targets.
Article Microbiology

Extensive C->U transition biases in the genomes of a wide range of mammalian RNA viruses; potential associations with transcriptional mutations, damage- or host-mediated editing of viral RNA

Peter Simmonds et al.

Summary: The study found a preponderance of C->U transitions in diverse mammalian RNA viruses, suggesting a potential RNA editing process driving this phenomenon. The presence of genome scale RNA secondary structure was significantly associated with C->U/U->C transition asymmetries, indicating a possible RNA structure dependence of sites targeted for C->U mutations. These C->U mutations accounted for a significant portion of standing sequence variability of structured viruses, potentially driving their sequence diversification and longer-term evolution.

PLOS PATHOGENS (2021)

Article Biochemistry & Molecular Biology

Host-directed editing of the SARS-CoV-2 genome

Tobias Mourier et al.

Summary: The extensive sequence data from SARS-CoV-2 in 2020 pandemic has facilitated the study of viral genome evolution, revealing instances of directional mutation pressures exerted on the genome by host antiviral defense systems. It discusses three human defense mechanisms – APOBEC, ADAR, and ROS – and their potential implications on SARS-CoV-2 evolution.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)

News Item Multidisciplinary Sciences

A NEW TWIST ON GENE EDITING

Sara Reardon

NATURE (2020)

Article Multidisciplinary Sciences

Pan-cancer analysis of whole genomes

Peter J. Campbell et al.

NATURE (2020)

Article Multidisciplinary Sciences

The repertoire of mutational signatures in human cancer

Ludmil B. Alexandrov et al.

NATURE (2020)

Article Multidisciplinary Sciences

APOBEC3B-mediated corruption of the tumor cell immunopeptidome induces heteroclitic neoepitopes for cancer immunotherapy

Christopher B. Driscoll et al.

NATURE COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

Daniel Blanco-Melo et al.

Article Fisheries

Characterization and functional analysis of chicken APOBEC4

Mengyu Shi et al.

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2020)

Article Multidisciplinary Sciences

Evidence for host-dependent RNA editing in the transcriptome of SARS-CoV-2

Salvatore Di Giorgio et al.

SCIENCE ADVANCES (2020)

Article Biochemistry & Molecular Biology

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

Mingfeng Liao et al.

NATURE MEDICINE (2020)

Article Biochemistry & Molecular Biology

ADAR1-mediated RNA editing is a novel oncogenic process in thyroid cancer and regulates miR-200 activity

Julia Ramirez-Moya et al.

ONCOGENE (2020)

Article Multidisciplinary Sciences

Quantification of ongoing APOBEC3A activity in tumor cells by monitoring RNA editing at hotspots

Pegah Jalili et al.

NATURE COMMUNICATIONS (2020)

Article Infectious Diseases

Emergence of genomic diversity and recurrent mutations in SARS-CoV-2

Lucy van Dorp et al.

INFECTION GENETICS AND EVOLUTION (2020)

Article Virology

Host Immune Response Driving SARS-CoV-2 Evolution

Rui Wang et al.

VIRUSES-BASEL (2020)

Article Biochemistry & Molecular Biology

The structure of APOBEC1 and insights into its RNA and DNA substrate selectivity

Aaron D. Wolfe et al.

NAR CANCER (2020)

Review Biochemical Research Methods

Critical review on engineering deaminases for site-directed RNA editing

Paul Vogel et al.

CURRENT OPINION IN BIOTECHNOLOGY (2019)

Article Biotechnology & Applied Microbiology

Precise RNA editing by recruiting endogenous ADARs with antisense oligonucleotides

Tobias Merkle et al.

NATURE BIOTECHNOLOGY (2019)

Article Multidisciplinary Sciences

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors

Julian Grunewald et al.

NATURE (2019)

Article Multidisciplinary Sciences

Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis

Changyang Zhou et al.

NATURE (2019)

Article Biotechnology & Applied Microbiology

Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs

Liang Qu et al.

NATURE BIOTECHNOLOGY (2019)

Article Multidisciplinary Sciences

A cytosine deaminase for programmable single-base RNA editing

Omar O. Abudayyeh et al.

SCIENCE (2019)

Article Biochemistry & Molecular Biology

Off-Target Editing by CRISPR-Guided DNA Base Editors

SeHee Park et al.

BIOCHEMISTRY (2019)

Review Medicine, Research & Experimental

RNA editing in the forefront of epitranscriptomics and human health

Theodoulakis Christofi et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2019)

Article Biochemistry & Molecular Biology

APOBEC3-Mediated RNA Editing in Breast Cancer is Associated with Heightened Immune Activity and Improved Survival

Mariko Asaoka et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Multidisciplinary Sciences

The deaminase APOBEC3B triggers the death of cells lacking uracil DNA glycosylase

Artur A. Serebrenik et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Biochemical Research Methods

Current strategies for Site-Directed RNA Editing using ADARs

Maria Fernanda Montiel-Gonzalez et al.

METHODS (2019)

Article Multidisciplinary Sciences

Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding

Hande Boyaci et al.

NATURE (2019)

Editorial Material Oncology

A-to-I RNA Editing: An Overlooked Source of Cancer Mutations

Shay Ben-Aroya et al.

CANCER CELL (2018)

Article Biochemistry & Molecular Biology

Differential Evolution of Antiretroviral Restriction Factors in Pteropid Bats as Revealed by APOBEC3 Gene Complexity

Joshua A. Hayward et al.

MOLECULAR BIOLOGY AND EVOLUTION (2018)

Article Biochemistry & Molecular Biology

The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism

Nadine M. Shaban et al.

MOLECULAR CELL (2018)

Article Biochemistry & Molecular Biology

DNA/RNA hybrid substrates modulate the catalytic activity of purified AID

Hala S. Abdouni et al.

MOLECULAR IMMUNOLOGY (2018)

Article Biochemical Research Methods

Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs

Paul Vogel et al.

NATURE METHODS (2018)

Review Genetics & Heredity

A-to-I RNA editing - immune protector and transcriptome diversifier

Eli Eisenberg et al.

NATURE REVIEWS GENETICS (2018)

Article Biochemistry & Molecular Biology

Structural basis of chimpanzee APOBEC3H dimerization stabilized by double-stranded RNA

Tatsuya Matsuoka et al.

NUCLEIC ACIDS RESEARCH (2018)

Review Biochemistry & Molecular Biology

Modeling the Embrace of a Mutator: APOBEC Selection of Nucleic Acid Ligands

Jason D. Salter et al.

TRENDS IN BIOCHEMICAL SCIENCES (2018)

Article Multidisciplinary Sciences

Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA

Atanu Maiti et al.

NATURE COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

APOBEC3-mediated restriction of RNA virus replication

Aleksandra Milewska et al.

SCIENTIFIC REPORTS (2018)

Article Biochemistry & Molecular Biology

APOBEC3H Subcellular Localization Determinants Define Zipcode for Targeting HIV-1 for Restriction

Daniel J. Salamango et al.

MOLECULAR AND CELLULAR BIOLOGY (2018)

Review Genetics & Heredity

Base editing: precision chemistry on the genome and transcriptome of living cells

Holly A. Rees et al.

NATURE REVIEWS GENETICS (2018)

Review Biochemistry & Molecular Biology

APOBEC Enzymes as Targets for Virus and Cancer Therapy

Margaret E. Olson et al.

CELL CHEMICAL BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B

Ke Shi et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)

Article Biochemistry & Molecular Biology

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B

Ke Shi et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)

Article Biochemistry & Molecular Biology

AID Recognizes Structured DNA for Class Switch Recombination

Qi Qiao et al.

MOLECULAR CELL (2017)

Review Genetics & Heredity

Detecting RNA modifications in the epitranscriptome: predict and validate

Mark Helm et al.

NATURE REVIEWS GENETICS (2017)

Article Multidisciplinary Sciences

Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology

Daniel C. Cole et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Epitranscriptomic profiling across cell types reveals associations between APOBEC1-mediated RNA editing, gene expression outcomes, and cellular function

Violeta Rayon-Estrada et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Biochemistry & Molecular Biology

APOBEC1 complementation factor (A1CF) is dispensable for C-to-U RNA editing in vivo

Elizabeth M. Snyder et al.

Article Multidisciplinary Sciences

APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA

Jennifer A. Bohn et al.

NATURE COMMUNICATIONS (2017)

Article Genetics & Heredity

Condition-specific RNA editing in the coral symbiont Symbiodinium microadriaticum

Yi Jin Liew et al.

PLOS GENETICS (2017)

Article Multidisciplinary Sciences

Stem-loop structure preference for site-specific RNA editing by APOBEC3A and APOBEC3G

Shraddha Sharma et al.

Article Multidisciplinary Sciences

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Alexis C. Komor et al.

NATURE (2016)

Article Multidisciplinary Sciences

APOBEC4 Enhances the Replication of HIV-1

Daniela Marino et al.

PLOS ONE (2016)

Article Multidisciplinary Sciences

Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage

Fuguo Jiang et al.

SCIENCE (2016)

Review Biochemistry & Molecular Biology

The APOBEC Protein Family: United by Structure, Divergent in Function

Jason D. Salter et al.

TRENDS IN BIOCHEMICAL SCIENCES (2016)

Article Multidisciplinary Sciences

The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer

Emily K. Law et al.

SCIENCE ADVANCES (2016)

Review Genetics & Heredity

Clusters of Multiple Mutations: Incidence and Molecular Mechanisms

Kin Chan et al.

ANNUAL REVIEW OF GENETICS, VOL 49 (2015)

Article Biochemistry & Molecular Biology

Non-coding RNA Generated following Lariat Debranching Mediates Targeting of AID to DNA

Simin Zheng et al.

Article Multidisciplinary Sciences

Tissue-based map of the human proteome

Mathias Uhlen et al.

SCIENCE (2015)

Review Virology

APOBECs and virus restriction

Reuben S. Harris et al.

VIROLOGY (2015)

Review Oncology

APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity

Charles Swanton et al.

CANCER DISCOVERY (2015)

Article Virology

APOBEC3A Functions as a Restriction Factor of Human Papillomavirus

Cody J. Warren et al.

JOURNAL OF VIROLOGY (2015)

Article Biochemistry & Molecular Biology

C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47

Nicolas Fossat et al.

EMBO REPORTS (2014)

Article Biochemistry & Molecular Biology

Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties

Mithun Mitra et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Biochemistry & Molecular Biology

The Local Dinucleotide Preference of APOBEC3G Can Be Altered from 5′-CC to 5′-TC by a Single Amino Acid Substitution

Anurag Rathore et al.

JOURNAL OF MOLECULAR BIOLOGY (2013)

Article Multidisciplinary Sciences

Signatures of mutational processes in human cancer

Ludmil B. Alexandrov et al.

NATURE (2013)

Article Genetics & Heredity

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

Steven A. Roberts et al.

NATURE GENETICS (2013)

Article Biochemistry & Molecular Biology

APOBEC3G cytosine deamination hotspots are defined by both sequence context and single-stranded DNA secondary structure

Colleen M. Holtz et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Biochemistry & Molecular Biology

HAMR: high-throughput annotation of modified ribonucleotides

Paul Ryvkin et al.

Article Biochemistry & Molecular Biology

APOBEC2 Is a Monomer in Solution: Implications for APOBEC3G Models

Troy C. Krzysiak et al.

BIOCHEMISTRY (2012)

Article Biochemistry & Molecular Biology

Mutational Processes Molding the Genomes of 21 Breast Cancers

Serena Nik-Zainal et al.

Article Biochemistry & Molecular Biology

Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions

Steven A. Roberts et al.

MOLECULAR CELL (2012)

Article Biochemistry & Molecular Biology

AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation

Christopher S. Nabel et al.

NATURE CHEMICAL BIOLOGY (2012)

Review Microbiology

Viral Quasispecies Evolution

Esteban Domingo et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2012)

Article Multidisciplinary Sciences

Transgenerational epigenetic effects of the Apobec1 cytidine deaminase deficiency on testicular germ cell tumor susceptibility and embryonic viability

Vicki R. Nelson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Biotechnology & Applied Microbiology

The ADAR protein family

Yiannis A. Savva et al.

GENOME BIOLOGY (2012)

Article Biochemistry & Molecular Biology

APOBEC3A can activate the DNA damage response and cause cell-cycle arrest

Sebastien Landry et al.

EMBO REPORTS (2011)

Review Biochemistry & Molecular Biology

Mechanisms and Consequences of Alternative Polyadenylation

Dafne Campigli Di Giammartino et al.

MOLECULAR CELL (2011)

Article Biochemistry & Molecular Biology

Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA-editing targets in transcript 3′ UTRs

Brad R. Rosenberg et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)

Review Biochemistry & Molecular Biology

Functions and Regulation of RNA Editing by ADAR Deaminases

Kazuko Nishikura

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79 (2010)

Article Biochemistry & Molecular Biology

Deficiency in APOBEC2 Leads to a Shift in Muscle Fiber Type, Diminished Body Mass, and Myopathy

Yusuke Sato et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Cell Biology

Lack of Apobec2-related proteins causes a dystrophic muscle phenotype in zebrafish embryos

Christelle Etard et al.

JOURNAL OF CELL BIOLOGY (2010)

Editorial Material Virology

Guidelines for Naming Nonprimate APOBEC3 Genes and Proteins

Rebecca S. LaRue et al.

JOURNAL OF VIROLOGY (2009)

Article Biochemistry & Molecular Biology

Active nuclear import and cytoplasmic retention of activation-induced deaminase

Anne-Marie Patenaude et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Human cytidine deaminase APOBEC3H restricts HIV-1 replication

Ying Dang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Interaction between anti body-diversification enzyme AID and spliceosome-associated factor CTNNBL1

Silvestro G. Conticello et al.

MOLECULAR CELL (2008)

Review Biotechnology & Applied Microbiology

The AID/APOBEC family of nucleic acid mutators

Silvestro G. Conticello

GENOME BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Single-stranded DNA structure and positional context of the target cytidine determine the enzymatic efficiency of AID

Mani Larijani et al.

MOLECULAR AND CELLULAR BIOLOGY (2007)

Article Multidisciplinary Sciences

The APOBEC-2 crystal structure and functional implications for the deaminase AID

Courtney Prochnow et al.

NATURE (2007)

Article Oncology

Aneuploidy acts both oncogenically and as a tumor suppressor

Beth A. A. Weaver et al.

CANCER CELL (2007)

Article Biochemistry & Molecular Biology

APOBEC-1 and AID are nucleo-cytoplasmic trafficking proteins but APOBEC3G cannot traffic

Ryan P. Bennett et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Review Biochemistry & Molecular Biology

Alternative splicing: New insights from global analyses

Benjamin J. Blencowe

Article Multidisciplinary Sciences

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations

AR Ramiro et al.

NATURE (2006)

Article Biochemistry & Molecular Biology

Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA

HC Losey et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)

Article Biochemistry & Molecular Biology

H2AX prevents DNA breaks from progressing to chromosome breaks and translocations

S Franco et al.

MOLECULAR CELL (2006)

Article Multidisciplinary Sciences

PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells

L Pasqualucci et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells

HP Bogerd et al.

NUCLEIC ACIDS RESEARCH (2006)

Article Biochemistry & Molecular Biology

Evolution of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases

SG Conticello et al.

MOLECULAR BIOLOGY AND EVOLUTION (2005)

Article Multidisciplinary Sciences

Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

S Ito et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G

SL Sawyer et al.

PLOS BIOLOGY (2004)

Article Biochemistry & Molecular Biology

APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo

MT Liddament et al.

CURRENT BIOLOGY (2004)

Review Immunology

Class-switch recombination: Interplay of transcription, DNA deamination and DNA repair

J Chaudhuri et al.

NATURE REVIEWS IMMUNOLOGY (2004)

Article Biochemistry & Molecular Biology

DNA determination mediates innate immunity to retroviral infection

RS Harris et al.

Article Biochemistry & Molecular Biology

In vitro deamination of cytosine to uracil in single-stranded DNA by apolipoprotein B editing complex catalytic subunit 1 (APOBEC1)

SK Petersen-Mahrt et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Immunology

AID mediates hypermutation by deaminating single stranded DNA

SK Dickerson et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2003)

Article Multidisciplinary Sciences

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

R Bransteitter et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators

RS Harris et al.

MOLECULAR CELL (2002)

Article Biochemistry & Molecular Biology

Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex

H Lellek et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)