4.8 Article

Machine learning-aided engineering of hydrolases for PET depolymerization

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biotechnology & Applied Microbiology

Non-Hydrolyzable Plastics - An Interdisciplinary Look at Plastic Bio-Oxidation

Hedda Inderthal et al.

Summary: Enzymatic plastic conversion is seen as a potential alternative to traditional plastic waste management, with a focus on biodegradable plastics such as polyesters. However, there are still challenges in applying enzymatic degradation to other commercial plastics. Addressing extensive knowledge gaps and understanding the crucial impact of physicochemical factors on reactions in less well-studied plastic types are essential for expanding the application of enzymatic degradation.

TRENDS IN BIOTECHNOLOGY (2021)

Article Chemistry, Physical

Computational Redesign of a PETase for Plastic Biodegradation under Ambient Condition by the GRAPE Strategy

Yinglu Cui et al.

Summary: This study successfully improved the robustness of PETase through a computational strategy, resulting in the redesign of a variant DuraPETase with significantly elevated melting temperature and enhanced degradation of PET films, as well as complete biodegradation of microplastics at mild temperatures. The design strategy presents opportunities for handling uncollectable PET waste and converting resulting monomers into high-value molecules.

ACS CATALYSIS (2021)

Review Multidisciplinary Sciences

The global threat from plastic pollution

Matthew MacLeo et al.

Summary: Plastic pollution that accumulates and is poorly reversible in the environment can have significant negative impacts such as changes to ecosystems, biological effects, and societal impacts. Therefore, a global response is needed to rapidly reduce plastic emissions through reductions in consumption of virgin plastic materials and internationally coordinated waste management strategies.

SCIENCE (2021)

Review Multidisciplinary Sciences

Plastic ingestion as an evolutionary trap: Toward a holistic understanding

Robson G. Santos et al.

Summary: Human activities are altering ecosystems globally, with plastic pollution playing a predominant role. Wildlife ingest plastic due to factors such as the availability of plastics in the environment, an individual's acceptance threshold, and the overlap of cues given by natural foods and plastics, as identified through the evolutionary trap theory.

SCIENCE (2021)

Article Chemistry, Physical

Molecular Insights into the Enhanced Performance of EKylated PETase Toward PET Degradation

Kun Chen et al.

Summary: The fusion of a zwitterionic polypeptide to PETase has been shown to enhance catalytic performance and increase product release in the degradation of highly crystallized PET films. Structural analysis and molecular simulations reveal the enhanced stability and substrate binding properties of EKylation-modified PETases.

ACS CATALYSIS (2021)

Review Chemistry, Physical

Chemical and biological catalysis for plastics recycling and upcycling

Lucas D. Ellis et al.

Summary: Plastic pollution is causing an environmental crisis, driving the development of new recycling and upcycling methods. Both chemical and biological catalysis face challenges and opportunities, requiring innovative design to overcome limitations.

NATURE CATALYSIS (2021)

Article Chemistry, Physical

General features to enhance enzymatic activity of poly(ethylene terephthalate) hydrolysis

Chun-Chi Chen et al.

Summary: The mutational strategy of replacing His/Phe residues with Ser/Ile has been found to enhance the PET-hydrolytic activity of enzymes, providing an important approach for improving the activity of potential PET-hydrolytic enzymes.

NATURE CATALYSIS (2021)

Review Chemistry, Multidisciplinary

Enzymatic degradation of plant biomass and synthetic polymers

Chun-Chi Chen et al.

NATURE REVIEWS CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

Current State and Perspectives Related to the Polyethylene Terephthalate Hydrolases Available for Biorecycling

Fusako Kawai et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2020)

Review Microbiology

Microbial Degradation and Valorization of Plastic Wastes

Jiakang Ru et al.

FRONTIERS IN MICROBIOLOGY (2020)

Article Multidisciplinary Sciences

An engineered PET depolymerase to break down and recycle plastic bottles

V. Tournier et al.

NATURE (2020)

Article Biochemical Research Methods

Discovery of Novel Gain-of-Function Mutations Guided by Structure-Based Deep Learning

Raghav Shroff et al.

ACS SYNTHETIC BIOLOGY (2020)

Review Biotechnology & Applied Microbiology

Current knowledge on enzymatic PET degradation and its possible application to waste stream management and other fields

Fusako Kawai et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2019)

Article Chemistry, Physical

Biodegradation of PET: Current Status and Application Aspects

Ikuo Taniguchi et al.

ACS CATALYSIS (2019)

Article Biochemical Research Methods

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

Dorothee Liebschner et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2019)

Article Multidisciplinary Sciences

Characterization and engineering of a plastic-degrading aromatic polyesterase

Harry P. Austin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Multidisciplinary Sciences

Structural insight into molecular mechanism of poly (ethylene terephthalate) degradation

Seongjoon Joo et al.

NATURE COMMUNICATIONS (2018)

Article Biochemical Research Methods

Genetic Engineering of Bee Gut Microbiome Bacteria with a Toolkit for Modular Assembly of Broad-Host-Range Plasmids

Sean P. Leonard et al.

ACS SYNTHETIC BIOLOGY (2018)

Article Multidisciplinary Sciences

Structural insight into catalytic mechanism of PET hydrolase

Xu Han et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

Production, use, and fate of all plastics ever made

Roland Geyer et al.

SCIENCE ADVANCES (2017)

Review Biotechnology & Applied Microbiology

Microbial enzymes for the recycling of recalcitrant petroleum-based plastics: how far are we?

Ren Wei et al.

MICROBIAL BIOTECHNOLOGY (2017)

Article Multidisciplinary Sciences

A bacterium that degrades and assimilates poly(ethylene terephthalate)

Shosuke Yoshida et al.

SCIENCE (2016)

Article Biotechnology & Applied Microbiology

A novel Ca2+-activated, thermostabilized polyesterase capable of hydrolyzing polyethylene terephthalate from Saccharomonospora viridis AHK190

Fusako Kawai et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2014)

Review Engineering, Chemical

Recent Developments in the Chemical Recycling of Postconsumer Poly(ethylene terephthalate) Waste

Neena George et al.

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH (2014)

Article Biochemical Research Methods

Coot:: model-building tools for molecular graphics

P Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)