4.8 Article

A multidimensional coding architecture of the vagal interoceptive system

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Neurosciences

Diversification of molecularly defined myenteric neuron classes revealed by single-cell RNA sequencing

Khomgrit Morarach et al.

Summary: Utilizing single-cell RNA sequencing, researchers identified 12 enteric neuron classes in the myenteric plexus of the mouse small intestine, revealing a novel principle of neuronal diversification during development. They found that two neuron classes arise through a binary neurogenic branching, while all other identities emerge through subsequent postmitotic differentiation.

NATURE NEUROSCIENCE (2021)

Article Neurosciences

Decoding Cellular Mechanisms for Mechanosensory Discrimination

Lars J. von Buchholtz et al.

Summary: Single-cell RNA-sequencing and in vivo functional imaging were used to investigate the molecular and cellular mechanisms of touch detection and encoding in the mammalian mechanosensory neurons. A transcriptomic logic responsible for the sensitivity and selectivity of these neurons was uncovered, with differential tuning of mechanosensory neurons by Piezo2 depending on cell class. This study demonstrates how mechanical stimuli recruit characteristic ensembles of transcriptomically defined neurons, providing rules to help explain touch discrimination.

NEURON (2021)

Article Biochemistry & Molecular Biology

The Gene Ontology resource: enriching a GOld mine

Seth Carbon et al.

Summary: The Gene Ontology Consortium has made advancements in the last two years, such as improving the GO-CAM annotation framework, increasing the number of annotations and annotated gene products, and reviewing older annotations for consistency.

NUCLEIC ACIDS RESEARCH (2021)

Review Neurosciences

Diseases, Disorders, and Comorbidities of Interoception

Bruno Bonaz et al.

Summary: Interoception, the perception of the body's internal physiological state, is crucial for homeostatic reflexes, motivational states, and emotional experiences. Aberrant integration and control of interoceptive signals can disrupt the system and are implicated in various disorders. Interoceptive mechanisms are central to disorders involving brain-body interactions, such as functional digestive disorders and chronic pain.

TRENDS IN NEUROSCIENCES (2021)

Review Neurosciences

The Emerging Science of Interoception: Sensing, Integrating, Interpreting, and Regulating Signals within the Self

Wen G. Chen et al.

Summary: Interoception refers to the representation of internal states in organisms, involving processes of sensing, interpreting, integrating, and regulating signals from within. This review provides a unified research framework, defines key terms, elaborates on research findings, and discusses central aspects of interoception, including anatomy, function, diseases, interventions, and challenges.

TRENDS IN NEUROSCIENCES (2021)

Review Neurosciences

Functions of Interoception: From Energy Regulation to Experience of the Self

Karen S. Quigley et al.

Summary: Interoceptive processing refers to how the nervous system anticipates, senses, and integrates signals originating from the body. Key functions of interoception include energy regulation, memory, affective experience, and the psychological sense of self. Multimodal integration occurs between interoceptive and exteroceptive modalities, and further empirical work is needed to understand where and how this integration happens.

TRENDS IN NEUROSCIENCES (2021)

Review Neurosciences

Neural Circuits of Interoception

Gary G. Berntson et al.

Summary: This paper reviews recent progress in understanding the afferent/ascending neural pathways and neural circuits involved in interoception, highlighting the crucial role of rostral neural systems in recognizing internal body states and the reciprocal role of efferent/descending systems in regulating these states. These interacting networks form interoceptive circuits that go beyond maintaining physiological steady-states and play a significant role in regulating behavioral, cognitive, and affective processes across conscious and nonconscious levels of processing. Important advances and knowledge gaps in the study of interoception are discussed to accelerate progress in this field.

TRENDS IN NEUROSCIENCES (2021)

Article Multidisciplinary Sciences

Organ-specific, multimodal, wireless optoelectronics for high-throughput phenotyping of peripheral neural pathways

Woo Seok Kim et al.

Summary: The study introduces a novel wireless optoelectronic device for precise and chronic in vivo optogenetic manipulations of peripheral neural circuits. The research uncovers the role of specific stomach neural fibers in suppressing appetite.

NATURE COMMUNICATIONS (2021)

Article Multidisciplinary Sciences

Optical vagus nerve modulation of heart and respiration via heart-injected retrograde AAV

Arjun K. Fontaine et al.

Summary: Optogenetic techniques can target neural communication with light-sensitive actuators for organ-specific neuromodulation. Stimulating vagus nerve fibers using photostimulation can induce changes in cardiac function, as demonstrated by alterations in heart rate, electrocardiogram, and respiratory responses. Retrograde labeling shows promise for organ-specific optical neuromodulation.

SCIENTIFIC REPORTS (2021)

Article Multidisciplinary Sciences

Trajectory-based differential expression analysis for single-cell sequencing data

Koen Van den Berge et al.

NATURE COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

An Airway Protection Program Revealed by Sweeping Genetic Control of Vagal Afferents

Sara L. Prescott et al.

Article Multidisciplinary Sciences

Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche

Mirza Muhammad Fahd Qadir et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Physiology

Spectrum of myelinated pulmonary afferents (III) cracking intermediate adapting receptors

Jerry Yu

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2020)

Article Biochemistry & Molecular Biology

The Human and Mouse Enteric Nervous System at Single-Cell Resolution

Eugene Drokhlyansky et al.

Article Biochemical Research Methods

Efficient sensory coding of multidimensional stimuli

Thomas E. Yerxa et al.

PLOS COMPUTATIONAL BIOLOGY (2020)

Article Biochemistry & Molecular Biology

AnimalTFDB 3.0: a comprehensive resource for annotation and prediction of animal transcription factors

Hui Hu et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Multidisciplinary Sciences

An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics

Ilias Angelidis et al.

NATURE COMMUNICATIONS (2019)

Article Cell Biology

An Atlas of Vagal Sensory Neurons and Their Molecular Specialization

Jussi Kupari et al.

CELL REPORTS (2019)

Review Multidisciplinary Sciences

Vagal innervation of the stomach reassessed: brain-gut connectome uses smart terminals

Terry L. Powley et al.

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2019)

Article Biochemistry & Molecular Biology

Comprehensive Integration of Single-Cell Data

Tim Stuart et al.

Article Biochemistry & Molecular Biology

Genetic Identification of Vagal Sensory Neurons That Control Feeding

Ling Bai et al.

Article Biochemistry & Molecular Biology

PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools

Huaiyu Mi et al.

NUCLEIC ACIDS RESEARCH (2019)

Review Biology

Fundamental principles of the olfactory code

Veit Grabe et al.

BIOSYSTEMS (2018)

Article Biotechnology & Applied Microbiology

Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics

Kelly Street et al.

BMC GENOMICS (2018)

Article Multidisciplinary Sciences

A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release

Constanza Alcaino et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Correction Biochemistry & Molecular Biology

A Neural Circuit for Gut-Induced Reward (vol 175, pg 665, 2018)

Wenfei Han et al.

Article Multidisciplinary Sciences

PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex

Wei-Zheng Zeng et al.

SCIENCE (2018)

Article Multidisciplinary Sciences

Piezo2 senses airway stretch and mediates lung inflation-induced apnoea

Keiko Nonomura et al.

NATURE (2017)

Review Multidisciplinary Sciences

From morphogen to morphogenesis and back

Darren Gilmour et al.

NATURE (2017)

Article Clinical Neurology

Nucleus of the solitary tract, medullary reflexes, and clinical implications

Jeremy K. Cutsforth-Gregory et al.

NEUROLOGY (2017)

Hardware Review Biophysics

An introduction into autonomic nervous function

John M. Karemaker

PHYSIOLOGICAL MEASUREMENT (2017)

Article Neurosciences

Tlx3 Function in the Dorsal Root Ganglion is Pivotal to Itch and Pain Sensations

Chengcheng Huang et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)

Article Biochemistry & Molecular Biology

Sensory Neurons that Detect Stretch and Nutrients in the Digestive System

Erika K. Williams et al.

Article Developmental Biology

Expression patterns of homeobox genes in the mouse vomeronasal organ at postnatal stages

Isabelle Chang et al.

GENE EXPRESSION PATTERNS (2016)

Review Physiology

VAGAL AFFERENT INNERVATION OF THE AIRWAYS IN HEALTH AND DISEASE

Stuart B. Mazzone et al.

PHYSIOLOGICAL REVIEWS (2016)

Article Biochemistry & Molecular Biology

Vagal Sensory Neuron Subtypes that Differentially Control Breathing

Rui B. Chang et al.

Article Biochemical Research Methods

Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging

Etsuo A. Susaki et al.

NATURE PROTOCOLS (2015)

Review Neurosciences

Peripheral Coding of Taste

Emily R. Liman et al.

NEURON (2014)

Article Biochemistry & Molecular Biology

The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons

Lishi Li et al.

Article Biochemistry & Molecular Biology

Common Sense about Taste: From Mammals to Insects

David A. Yarmolinsky et al.

Article Gastroenterology & Hepatology

Neuroanatomy of extrinsic afferents supplying the gastrointestinal tract

HR Berthoud et al.

NEUROGASTROENTEROLOGY AND MOTILITY (2004)

Article Cardiac & Cardiovascular Systems

Development of the heart: (1) - Formation of the cardiac chambers and arterial trunks

A Moorman et al.

Article Gastroenterology & Hepatology

Musings on the wanderer: What's new in our understanding of vago-vagal reflexes? II. Integration of afferent signaling from the viscera by the nodose ganglia

KN Browning et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2003)

Article Neurosciences

Functional and chemical anatomy of the afferent vagal system

HR Berthoud et al.

AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2000)

Article Multidisciplinary Sciences

Damage-induced neuronal endopeptidase (DINE) is a unique metallopeptidase expressed in response to neuronal damage and activates superoxide scavengers

S Kiryu-Seo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)