4.8 Article

Oxygen vacancy-engineered BaTiO3 nanoparticles for synergistic cancer photothermal, photodynamic, and catalytic therapy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Multidisciplinary

H2O2 Self-Producing Single-Atom Nanozyme Hydrogels as Light-Controlled Oxidative Stress Amplifier for Enhanced Synergistic Therapy by Transforming Cold Tumors

Daoming Zhu et al.

Summary: A light-controlled oxidative stress amplifier system is designed in this study, showing synergistic antitumor activity in solid tumors. The system self-produces H2O2 and transforms cold tumors, and the combination of photothermal therapy, chemotherapy, and nanozyme-based catalytic therapy further enhances tumor immunogenic death and antitumor immunity.

ADVANCED FUNCTIONAL MATERIALS (2022)

Article Chemistry, Physical

Mesoporous radiosensitized nanoprobe for enhanced NIR-II photoacoustic imaging-guided accurate radio-chemotherapy

Tao Chen et al.

Summary: This study presents a novel theranostics nanoplatform for cancer therapy and diagnosis, incorporating tungsten trioxide, gold nanoparticles, and up-conversion nanoparticles. The nanoplatform improves photoacoustic imaging performance and acts as an efficient radiosensitizer for radio-chemo anti-cancer therapy. Additionally, it accurately guides cancer radiotherapy and reduces side effects on normal tissues.

NANO RESEARCH (2022)

Review Chemistry, Physical

Photocatalytic nitrogen reduction to ammonia: Insights into the role of defect engineering in photocatalysts

Huidong Shen et al.

Summary: This review highlights the importance of defect engineering in semiconductors for improving photocatalytic N-2 conversion efficiency, focusing on the state-of-the-art progress in defect engineering of photocatalysts for N-2 reduction toward ammonia. Key aspects covered include basic principles, defect classification, synthesis strategies, and characterization techniques.

NANO RESEARCH (2022)

Article Chemistry, Physical

Black phosphorus quantum dots as multifunctional nanozymes for tumor photothermal/catalytic synergistic therapy

Hui Ding et al.

Summary: The study developed biomimetic erythrocyte membrane-camouflaged ultrasmall black phosphorus quantum dots (BPQDs) nanozymes that exhibited exceptional near-infrared photothermal property and significantly enhanced glucose oxidase-like activity in the acidic tumor microenvironment, providing an effective therapeutic strategy for inhibiting tumor growth.

NANO RESEARCH (2022)

Article Chemistry, Multidisciplinary

Localized surface plasmon resonance properties and biomedical applications of copper selenide nanomaterials

K. Ai et al.

Summary: Copper selenide nanomaterials with LSPR properties in the near-infrared region have broad applications in biomedicine, offering advantages such as biocompatibility and strong chemical tunability. However, there is currently no comprehensive review on the research of copper selenide nanomaterials in biomedicine.

MATERIALS TODAY CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

2D Piezoelectric Bi2MoO6 Nanoribbons for GSH-Enhanced Sonodynamic Therapy

Yushan Dong et al.

Summary: In this study, ultrathin 2D Bi2MoO6-poly(ethylene glycol) nanoribbons were designed as piezoelectric sonosensitizers for sonodynamic therapy (SDT), aiming to reduce the scavenging capacity of reactive oxygen species (ROS) and elevate ROS production by consuming endogenous GSH and promoting electron-hole pair separation. The synthesized nanoribbons showed excellent computed tomography imaging of tumors and significant tumor suppression in vitro and in vivo, demonstrating a potential two-step enhancement SDT process activated by endogenous GSH and amplified by exogenous ultrasound.

ADVANCED MATERIALS (2021)

Article Chemistry, Physical

Defect-rich titanium nitride nanoparticle with high microwave-acoustic conversion efficiency for thermoacoustic imaging-guided deep tumor therapy

Zhujun Wu et al.

Summary: Nanoparticles are promising for precise tumor therapy through pulse microwave excited thermoacoustic (MTA) treatment, which efficiently destroys tumor cells while providing valuable imaging information for treatment planning and monitoring.

NANO RESEARCH (2021)

Article Chemistry, Multidisciplinary

A Multifunctional Nanovaccine based on L-Arginine-Loaded Black Mesoporous Titania: Ultrasound-Triggered Synergistic Cancer Sonodynamic Therapy/Gas Therapy/Immunotherapy with Remarkably Enhanced Efficacy

Meifang Wang et al.

Summary: The multifunctional nanovaccine based on BMT@LA combined with αPD-L1 antibody can induce a strong antitumor immune response, effectively killing primary tumors and inhibiting metastatic tumors. This combination treatment realizes synergetic sonodynamic/gas/immunotherapy with enhanced antitumor therapeutic effects.
Article Chemistry, Multidisciplinary

High-Performance Self-Cascade Pyrite Nanozymes for Apoptosis-Ferroptosis Synergistic Tumor Therapy

Xiangqin Meng et al.

Summary: The pyrite peroxidase nanozyme demonstrates ultra-high affinity for H2O2 and possesses intrinsic glutathione oxidase-like activity, resulting in abundant production of (OH)-O-center dot and depletion of reduced glutathione, inducing apoptosis and ferroptosis of tumor cells. It shows potential for effective therapeutic application in tumor catalytic therapy.

ACS NANO (2021)

Article Chemistry, Multidisciplinary

Magnetic-Field-Stimulated Efficient Photocatalytic N2 Fixation over Defective BaTiO3 Perovskites

Zhao Zhao et al.

Summary: Efficient photocatalytic nitrogen fixation with high NH3 yield rate was achieved under an applied magnetic field using defective BaTiO3 perovskite. Manipulation of surface spin states and oxygen vacancies stimulated an electromagnetic synergistic effect between internal and external fields, suppressing carrier recombination and promoting N-2 adsorption and activation.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

Unveiling the active sites on ferrihydrite with apparent catalase-like activity for potentiating radiotherapy

Ruofei Zhang et al.

Summary: Nanozymes with catalase-like activity, especially ferrihydrite, show potential in relieving tumor hypoxia for adjuvant radiotherapy. The surface iron-associated hydroxyl groups of ferrihydrite dominantly affect its catalytic activity. Moreover, ferrihydrite constantly catalyzes the decomposition of H2O2 to release O-2 in a specific pH range, enhancing the therapeutic effect of radiotherapy in the physiological environment.

NANO TODAY (2021)

Article Chemistry, Multidisciplinary

Conferring Ti-Based MOFs with Defects for Enhanced Sonodynamic Cancer Therapy

Shuang Liang et al.

Summary: Researchers have developed a novel sonosensitizer D-MOF(Ti) for enhanced sonodynamic therapy, which exhibits superior ROS yield and Fenton-like activity under ultrasound irradiation. The synergistic outcomes of sonodynamic and chemodynamic therapy have been achieved using ultrasound as the excitation source.

ADVANCED MATERIALS (2021)

Article Chemistry, Multidisciplinary

Strain-Engineered Nano-Ferroelectrics for High-Efficiency Piezocatalytic Overall Water Splitting

Ran Su et al.

Summary: The study successfully enhanced the piezoelectricity of BaTiO3 nanoparticles by inducing heteroepitaxial strain through surface reconstruction, leading to significantly improved water-splitting activity. This approach offers a generic method for designing highly efficient piezoelectric nanomaterials and has potential applications in other perovskite oxides.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Engineering, Biomedical

Engineering oxygen-deficient ZrO2-x nanoplatform as therapy-activated immunogenic cell death (ICD) inducer to synergize photothermal-augmented sonodynamic tumor elimination in NIR-II biological window

Xiaodan Jiao et al.

Summary: An oxygen-deficient zirconia-based nanoplatform, surface PEGylated and cyclic-Arg-Gly-Asp (cRGD) peptide functionalized, was designed for therapy-activated immunogenic cell death induction to enhance photothermal-augmented sonodynamic tumor elimination. This study demonstrates the potential of zirconia in tumor theranostics as a promising translational medicine.

BIOMATERIALS (2021)

Article Materials Science, Multidisciplinary

Noninvasive manipulation of cell adhesion for cell harvesting with piezoelectric composite film

Xingyi Wan et al.

Summary: Cell sheet harvesting is a promising strategy for scaffold-free cell transplantation and tissue engineering, which requires modulating cell adhesion behavior. Recent research demonstrates a noninvasive and highly efficient cell harvesting method based on the piezoelectric effect, which shows great application prospects in cell sheet engineering.

APPLIED MATERIALS TODAY (2021)

Review Engineering, Biomedical

MoS2-based nanocomposites for cancer diagnosis and therapy

Jianling Wang et al.

Summary: Molybdenum is an essential trace element for human survival. MoS2-nanomaterials have unique properties that make them attractive for cancer diagnosis and treatment, such as adsorbing biomolecules and drugs for improved targeting and accuracy, as well as excellent photothermal conversion efficiency for therapy.

BIOACTIVE MATERIALS (2021)

Article Chemistry, Multidisciplinary

Oxygen Vacancy-Driven Reversible Free Radical Catalysis for Environment-Adaptive Cancer Chemodynamic Therapy

Xi Yuan et al.

Summary: The article introduces a Bi-based regulator with oxygen vacancy-rich properties that enables environment-adaptive free radical catalysis in cancer cells, while also clearing accumulation of free radicals and immunosuppressive mediators in noncancerous cells associated with the tumor microenvironment (TME).

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

A Titanium Nitride Nanozyme for pH-Responsive and Irradiation-Enhanced Cascade-Catalytic Tumor Therapy

Jiaming Liu et al.

Summary: The study found that nitrogen doping significantly enhanced the peroxidase activity of titanium-based nanozymes, and further improved the catalytic activity of nanozymes under near-infrared laser irradiation. By using TLGp, combining pH-responsive GOx-mediated H2O2 self-supply, nitrogen doping, and irradiation-enhanced enzymatic activity of titanium nitride nanoparticles, along with mild photothermal therapy, effective tumor inhibition with minimal side effects in vivo was achieved.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

Defect Engineering Enables Synergistic Action of Enzyme-Mimicking Active Centers for High-Efficiency Tumor Therapy

Bin Yu et al.

Summary: This study demonstrates the development of a simple yet efficient redox nanozyme through defect engineering, which enhances binding capacity and catalytic activity, leading to substantial disruption of redox and metabolism homeostasis in the tumor region.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Chemistry, Multidisciplinary

Plasmon-pyroelectric nanostructures used to produce a temperature-mediated reactive oxygen species for hypoxic tumor therapy

Yun Chang et al.

Summary: The newly designed Au@BTO CSNSs nanostructures generate a temperature-mediated oxygen-independent PDT, which can play a significant role in hypoxic tumor microenvironment and show great potential for hypoxic tumor therapy.

NANO TODAY (2021)

Article Chemistry, Multidisciplinary

NIR-Triggered Multi-Mode Antitumor Therapy Based on Bi2Se3/Au Heterostructure with Enhanced Efficacy

Chunzheng Yang et al.

Summary: In this study, Bi2Se3/Au heterostructured photocatalysts were fabricated to address the rapid recombination of electron-hole pairs, enhancing efficient ROS generation and improving photothermal efficiency. The introduction of PLGA-PEG and DOX enabled photothermal-triggered drug release, and the heterostructures demonstrated excellent dual-modal imaging properties for cancer diagnosis. The research shows promising tumor inhibition effect based on synchronous PTT, PCT, and chemotherapy triggered by NIR light for efficient antitumor treatment.
Article Chemistry, Physical

Ultrasound-activated Au/ZnO-based Trojan nanogenerators for combined targeted electro-stimulation and enhanced catalytic therapy of tumor

Kongshuo Ma et al.

Summary: The ultrasound-activated Trojan nanogenerators based on Au/ZnO are able to achieve targeted electrostimulation and enhanced catalytic therapy for tumor treatment.

NANO ENERGY (2021)

Article Chemistry, Multidisciplinary

Ultrafine Titanium Monoxide (TiO1+x) Nanorods for Enhanced Sonodynamic Therapy

Xianwen Wang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Review Oncology

Clinical development and potential of photothermal and photodynamic therapies for cancer

Xingshu Li et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2020)

Article Chemistry, Physical

Defect engineering of 2D BiOCl nanosheets for photonic tumor ablation

Chen Dai et al.

NANOSCALE HORIZONS (2020)

Article Chemistry, Multidisciplinary

Homojunction of Oxygen and Titanium Vacancies and its Interfacial n-p Effect

Si-Ming Wu et al.

ADVANCED MATERIALS (2018)

Article Chemistry, Multidisciplinary

Defect Effects on TiO2 Nanosheets: Stabilizing Single Atomic Site Au and Promoting Catalytic Properties

Jiawei Wan et al.

ADVANCED MATERIALS (2018)

Review Chemistry, Multidisciplinary

Tungsten Oxides for Photocatalysis, Electrochemistry, and Phototherapy

Zhen-Feng Huang et al.

ADVANCED MATERIALS (2015)

Article Chemistry, Multidisciplinary

Efficient Visible Light Nitrogen Fixation with BiOBr Nanosheets of Oxygen Vacancies on the Exposed {001} Facets

Hao Li et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)