NIR-II Responsive Molybdenum Dioxide Nanosystem Manipulating Cellular Immunogenicity for Enhanced Tumor Photoimmunotherapy

Article Chemistry, Multidisciplinary

Oligomycin A Induces Apoptosis-to-Pyroptosis Switch against Melanoma with Sensitized Immunotherapy

Liying Wang et al.

Summary: Mitochondrial-targeted therapies have shown effectiveness in inducing programmed cell death in malignant melanoma, with potential clinical applications in triggering the switch from apoptosis to pyroptosis for cancer treatment.

ADVANCED FUNCTIONAL MATERIALS (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Electromagnetic Nanomedicines for Combinational Cancer Immunotherapy

Jingchao Li et al.

Summary: Immunotherapy harnesses the immune system to eliminate malignant cells, but faces challenges such as limited patient response rates and immune-related adverse events. Electromagnetic nanomaterials can induce immunogenic cell death and are used in combination with cancer immunotherapy for reprogramming the tumor microenvironment.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Review Engineering, Biomedical

Near-infrared-II activated inorganic photothermal nanomedicines

Zhongzheng Yu et al.

Summary: The emergence of NIR-II activated photomedicines has significantly expanded the penetration depth for noninvasive theranostics; However, there is a lack of thorough review for NIR-II inorganic PTAs, with most comparisons made with NIR-I PTAs; This review aims to inspire further development of NIR-II activated inorganic PTAs with good photothermal conversion ability and potential biomedical applications.

BIOMATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Regioselectively Oxidized 2D Bi/BiOx Lateral Nano-Heterostructure for Hypoxic Photodynamic Therapy

Meng Qiu et al.

Summary: Optoelectronic science and 2D nanomaterial technologies are leading multidisciplinary research with applications in electronics and photonics. The unique energy and optically induced interfacial electron transfer in nanomaterials can provide important therapeutic modalities for healthcare. A lateral nano-heterostructure based on bismuthene/bismuth oxide (Bi/BiOx) synthesized using regioselective oxidation process shows promising results in photodynamic therapy, offering improvements in tumor ablation and biocompatibility.

ADVANCED MATERIALS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Recent Advances in Hyperthermia Therapy-Based Synergistic Immunotherapy

Mengyu Chang et al.

Summary: Hyperthermia therapy has emerged as a strategy against malignant tumors, particularly when combined with nanomaterial-based photothermal therapy or magnetic hyperthermia. While these treatments alone may not completely cure cancer, when combined with cancer immunotherapy, they have shown potential for enhanced therapeutic outcomes against both primary tumors and metastatic lesions, as well as preventing cancer recurrence and prolonging survival period.

ADVANCED MATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Activatable NIR-II Plasmonic Nanotheranostics for Efficient Photoacoustic Imaging and Photothermal Cancer Therapy

Chunyu Zhou et al.

Summary: The study presents a transformable chain structure based on gold nanochains that can be activated in the tumor microenvironment, exhibiting strong NIR-II absorption and excellent properties for tumor treatment.

ADVANCED MATERIALS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress

Zhusheng Huang et al.

Summary: The study demonstrates a strategy of using gadolinium-based nanoscale coordination polymers to enhance radiation-induced immunogenic cell death, thereby boosting anti-tumor immune responses.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Review Oncology

Fueling the Fire: Inflammatory Forms of Cell Death and Implications for Cancer Immunotherapy

Sheera R. Rosenbaum et al.

Summary: Using immune checkpoint inhibitors (ICI) has significantly improved overall survival for certain cancer patients, but many tumors do not respond due to a lack of tumor-infiltrating lymphocytes (TIL). Converting immune cold tumors to hot tumors is a key obstacle in cancer treatment. Promoting tumor-localized necroptosis and pyroptosis may enhance responses to ICI.

CANCER DISCOVERY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Manganese-Dioxide-Coating-Instructed Plasmonic Modulation of Gold Nanorods for Activatable Duplex-Imaging-Guided NIR-II Photothermal-Chemodynamic Therapy

Ting He et al.

Summary: A plasmonic modulation strategy of gold nanorods through manganese dioxide coating has been developed for NIR-II photoacoustic/magnetic resonance imaging-guided photothermal chemodynamic therapy. The LSPR peak of gold nanorods can be tuned by adjusting the thickness of the MnO2 layer, and the MnO2 layer can degrade in the tumor microenvironment for MR imaging and chemodynamic therapy. This strategy can be applied to other metal nanomaterials for construction of a new class of NIR-II nanotheranostics.

ADVANCED MATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Biodegradable Upconversion Nanoparticles Induce Pyroptosis for Cancer Immunotherapy

Binbin Ding et al.

Summary: This study proposes biodegradable K3ZrF7:Yb/Er upconversion nanoparticles (ZrNPs) as pyroptosis inducers for cancer immunotherapy, which can release ions to induce intracellular osmotic imbalance and trigger cell death mechanisms. In vivo tests confirm that ZrNPs-induced pyroptosis exhibits superior antitumor immunity activity, inhibiting tumor growth and pulmonary metastasis.

NANO LETTERS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer

Yuyan Jiang et al.

Summary: The authors present a strategy for controlled immune regulation in cancer nano-immunotherapy using a photothermally activatable semiconducting polymeric pro-agonist responsive to second near-infrared window light.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Article Engineering, Biomedical

Redox responsive nanoparticle encapsulating black phosphorus quantum dots for cancer theranostics

Haolin Chen et al.

Summary: The study developed a biodegradable and biocompatible black phosphorus-based nanoagent for cancer diagnosis and therapy. This nanoagent has excellent photothermal properties and drug delivery capacity, serving as a novel therapeutic platform with low dosage and side effects. Both the polymer and BPQD are degradable, indicating this platform is a rare PT-OCT agent that is completely biodegradable.

BIOACTIVE MATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Microenvironment-Responsive Prodrug-Induced Pyroptosis Boosts Cancer Immunotherapy

Yao Xiao et al.

Summary: The absence of tumor antigens poses a challenge in ICB therapy, but inducing tumor-specific pyroptosis while reducing injury in normal tissues is urgently needed. A ROS/GSH dual-responsive nano-prodrug called MCPP with high PTX and P18 loading is designed to selectively induce pyroptosis in tumor cells. Chemo-photodynamic therapy and controlled-release PTX synergistically induce pyroptosis, releasing DAMPs and enhancing ICB efficiency, suggesting a smart strategy to trigger pyroptosis and augment ICB efficiency.

ADVANCED SCIENCE (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy

Chi Zhang et al.

Summary: Proteolysis targeting chimeras (PROTACs) offer an alternative way to modulate protein homeostasis for cancer therapy, but existing PROTACs may have uncontrollable protein degradation and off-target side effects. This study presents a semiconducting polymer nano-PROTAC (SPNpro) with phototherapeutic and activatable protein degradation abilities for photo-immunometabolic cancer therapy. SPNpro can generate singlet oxygen under NIR photoirradiation to eradicate tumor cells and activate protein degradation specifically in response to a cancer biomarker, enhancing tumor immunogenicity.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Nanopoxia: Targeting Cancer Hypoxia by Antimonene-Based Nanoplatform for Precision Cancer Therapy

Meng Qiu et al.

Summary: Most anticancer drugs are distributed unevenly in tumors, leading to severe adverse effects; Nanopoxia technology releases therapeutic agents based on tumor hypoxia, achieving precision cancer therapy; This approach demonstrates high efficacy in preclinical cancer models.

ADVANCED FUNCTIONAL MATERIALS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

NIR-II Responsive Inorganic 2D Nanomaterials for Cancer Photothermal Therapy: Recent Advances and Future Challenges

Dong An et al.

Summary: Non-invasive cancer photothermal therapy (PTT) shows potential as a replacement for traditional cancer treatments, with recent developments focusing on NIR-II PTT and the use of inorganic 2D nanomaterials as photothermal agents (PTAs) to enhance efficiency. Strategies integrating NIR-II responsive PTT with other treatment approaches are promising for advancing cancer therapy.

ADVANCED FUNCTIONAL MATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Charge-Reversal Polymer Nano-modulators for Photodynamic Immunotherapy of Cancer

Shasha He et al.

Summary: The study presents a charge-reversal polymer nano-modulator activated by tumor micro-environment for photodynamic immunotherapy of cancer. This nano-modulator regulates the balance between CTLs and Tregs, promotes dendritic cell maturation, and effectively inhibits both primary and distant tumors.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Engineering, Biomedical

Black phosphorous nanosheet: A novel immune-potentiating nanoadjuvant for near-infrared-improved immunotherapy

Wen-Hao Li et al.

Summary: The research explores the immune-potentiating effects of black phosphorus nanosheets for cancer immunotherapy. By using a multifunctional nanoadjuvant, high loading capacity, efficient drug delivery, DC activation, and biocompatibility are integrated to enhance antitumor immunity. Additionally, near-infrared photothermal effects create an immune-favorable microenvironment for improved local immunization.

BIOMATERIALS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Second near-infrared photothermal materials for combinational nanotheranostics

Cheng Xu et al.

Summary: Second near-infrared photothermal therapy (NIR-II PTT) has advantages of deeper penetration and less toxicity, but faces challenges of suboptimal photothermal conversion and limited therapeutic efficacy. To improve efficacy, multifunctional NIR-II photothermal inorganic or organic materials have been developed for combination with other therapeutic modalities.

CHEMICAL SOCIETY REVIEWS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Necroptosis-Inducible Polymeric Nanobubbles for Enhanced Cancer Sonoimmunotherapy

Wooram Um et al.

ADVANCED MATERIALS (2020)

添加到收藏夹

Article Engineering, Environmental

In situ photothermal activation of necroptosis potentiates black phosphorus-mediated cancer photo-immunotherapy

Henan Zhao et al.

CHEMICAL ENGINEERING JOURNAL (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Engineering a Therapy-Induced Immunogenic Cancer Cell Death Amplifier to Boost Systemic Tumor Elimination

Bei Li et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Fine-Tuning the Homometallic Interface of Au-on-Au Nanorods and Their Photothermal Therapy in the NIR-II Window

Jia Jia et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Highly Efficient 2D NIR-II Photothermal Agent with Fenton Catalytic Activity for Cancer Synergistic Photothermal-Chemodynamic Therapy

Qiuhong Zhang et al.

ADVANCED SCIENCE (2020)

添加到收藏夹

Article Materials Science, Multidisciplinary

Insights into the deep-tissue photothermal therapy in near-infrared II region based on tumor-targeted MoO2 nanoaggregates

Yanxian Guo et al.

SCIENCE CHINA-MATERIALS (2020)

添加到收藏夹

Review Oncology

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

Lorenzo Galluzzi et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)

添加到收藏夹

Review Oncology

Ferroptosis, necroptosis, and pyroptosis in anticancer immunity

Rong Tang et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Liposomal Delivery of Mitoxantrone and a Cholesteryl Indoximod Prodrug Provides Effective Chemo-immunotherapy in Multiple Solid Tumors

Kuo-Ching Mei et al.

ACS NANO (2020)

添加到收藏夹

Review Oncology

Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors

Lorenzo Galluzzi et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Inhibition of PCSK9 potentiates immune checkpoint therapy for cancer

Xinjian Liu et al.

NATURE (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Prodrug-Loaded Zirconium Carbide Nanosheets as a Novel Biophotonic Nanoplatform for Effective Treatment of Cancer

Quan Liu et al.

ADVANCED SCIENCE (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Low-Cost Titanium-Bromine Flow Battery with Ultrahigh Cycle Stability for Grid-Scale Energy Storage

Xianjin Li et al.

ADVANCED MATERIALS (2020)

添加到收藏夹

Review Oncology

Novel Forms of Immunomodulation for Cancer Therapy

Alfonso Serrano-del Valle et al.

TRENDS IN CANCER (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Molecular and nanoengineering approaches towards activatable cancer immunotherapy

Chi Zhang et al.

CHEMICAL SOCIETY REVIEWS (2020)

添加到收藏夹

Review Materials Science, Biomaterials

Progress in the therapeutic applications of polymer-decorated black phosphorus and black phosphorus analog nanomaterials in biomedicine

Dong An et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Nanoparticle-Mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy

Xiaopin Duan et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Inorganic Nanoshell-Stabilized Liquid Metal for Targeted Photonanomedicine in NIR-II Biowindow

Piao Zhu et al.

NANO LETTERS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

NIR-Triggered Phototherapy and Immunotherapy via an Antigen-Capturing Nanoplatform for Metastatic Cancer Treatment

Meng Wang et al.

ADVANCED SCIENCE (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Near-Infrared Photoimmunotherapy of Cancer

Hisataka Kobayashi et al.

ACCOUNTS OF CHEMICAL RESEARCH (2019)

添加到收藏夹

Article Immunology

Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity

Annelise G. Snyder et al.

SCIENCE IMMUNOLOGY (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis

Kim Newton et al.

NATURE (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

Melanie Fritsch et al.

NATURE (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Activity of caspase-8 determines plasticity between cell death pathways

Kim Newton et al.

NATURE (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

Comparing the effects of different cell death programs in tumor progression and immunotherapy

Michelle N. Messmer et al.

CELL DEATH AND DIFFERENTIATION (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Surgical Tumor-Derived Personalized Photothermal Vaccine Formulation for Cancer Immunotherapy

Xinyu Ye et al.

ACS NANO (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Polypeptide-Conjugated Second Near-Infrared Organic Fluorophore for Image-Guided Photothermal Therapy

Tuanwei Li et al.

ACS NANO (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade

Fangyuan Zhou et al.

ADVANCED MATERIALS (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Nanomedicine and macroscale materials in immuno-oncology

Qingxue Sun et al.

CHEMICAL SOCIETY REVIEWS (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Optical nano-agents in the second near-infrared window for biomedical applications

Yu Cai et al.

CHEMICAL SOCIETY REVIEWS (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Omnipotent phosphorene: a next-generation, two-dimensional nanoplatform for multidisciplinary biomedical applications

Meng Qiu et al.

CHEMICAL SOCIETY REVIEWS (2018)

添加到收藏夹

Article Multidisciplinary Sciences

Novel concept of the smart NIR-light-controlled drug release of black phosphorus nanostructure for cancer therapy

Meng Qiu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

添加到收藏夹

Article Cell Biology

Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity

Tania Love Aaes et al.

CELL REPORTS (2016)

添加到收藏夹

Review Oncology

Immunogenic cell death and DAMPs in cancer therapy

Dmitri V. Krysko et al.

NATURE REVIEWS CANCER (2012)

添加到收藏夹

Article Physics, Applied

Optical properties of human skin, subcutaneous and mucous tissues in the wavelength range from 400 to 2000 nm

AN Bashkatov et al.

JOURNAL OF PHYSICS D-APPLIED PHYSICS (2005)

添加到收藏夹

NIR-II Responsive Molybdenum Dioxide Nanosystem Manipulating Cellular Immunogenicity for Enhanced Tumor Photoimmunotherapy

相关参考文献

导出引文

分享论文