Prediction of epileptic seizures from spectral features of intracranial eeg recordings using deep learning approach

Epilepsy is a prevalent neurological disorder, which disturbs the lives of millions of people worldwide owing to the onset of abrupt seizures. The forecasting of seizures could help in protecting their lives by alerts or in clinical operations during epilepsy surgeries. The present paper addresses this problem by proposing a deep learning framework for prediction of epileptic seizures using intracranial EEG (iEEG) recordings. This framework performs filtering and segmentation of iEEG signals into 10s, 20s, 30s, 40s, 50s and 60s duration segments. These segments are further resolved into eight distinct spectral bands corresponding to delta, theta, alpha, beta and gamma sub-bands with frequency-domain transformation. Then, mean amplitude and band power features are extracted from each band, which are provided to convolutional neural network (CNN) and long short-term memory network (LSTM) algorithms for classification. The simulation results of the proposed CNN model exhibit higher performance with average accuracy, sensitivity, specificity, AUC and F1 score of 94.74%, 95.8%, 94.46%, 95.13% and 94.75% respectively for iEEG segments of 40s duration. Thus, the performance analysis and comparison with existing literature unveil that the proposed CNN model is an optimal approach for accurate and real-time prediction of epileptic seizures.

Automated summary

In this paper, a deep learning framework is proposed for the prediction of epileptic seizures using intracranial EEG recordings. The framework performs signal filtering and segmentation, and extracts features from each segment to achieve accurate and real-time prediction of epileptic seizures.