4.6 Article

Cloning and Functional Characterization of Two Germacrene A Oxidases Isolated from Xanthium sibiricum

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Summary: 8,12-sesquiterpene lactones (STLs) are important natural products with unique pharmaceutical activities. This study reports the characterization of a unique germacrene A oxidase (XsGAO) from X. strumarium, which catalyzes a one-step conversion of germacrene A to germacrene A alcohol, unlike the known enzyme reactions.

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