4.7 Article

Unveiling the genomic structures and evolutionary events of the saxitoxin biosynthetic gene sxtA in the marine toxic dinoflagellate Alexandrium

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Environmental Sciences

Temperature influences the content and biosynthesis gene expression of saxitoxins (STXs) in the toxigenic dinoflagellate Alexandrium pacificum

Hui Wang et al.

Summary: The study found that temperature significantly affects cell growth and toxin production in toxic dinoflagellates, with 16 degrees Celsius being the most favorable temperature for cell growth. Lower temperatures and exposure to cold stress can increase the expression of toxin biosynthesis genes, while heat stress can downregulate the transcription of these genes. These results suggest that temperature may be a critical factor affecting the level and biosynthesis of toxins in marine toxic dinoflagellates.

SCIENCE OF THE TOTAL ENVIRONMENT (2022)

Article Marine & Freshwater Biology

Overview of Australian and New Zealand harmful algal species occurrences and their societal impacts in the period 1985 to 2018, including a compilation of historic records

Gustaaf M. Hallegraeff et al.

Summary: Australia and New Zealand both have similarities and differences in terms of harmful algal species occurrences and their impacts on human society, such as toxic shellfish toxin production. While both countries have experienced harmful algal events, the predominant seafood toxin syndromes differ between Australia and New Zealand.

HARMFUL ALGAE (2021)

Article Marine & Freshwater Biology

The Latin America and Caribbean HAB status report based on OBIS and HAEDAT maps and databases

Ines Sunesen et al.

Summary: Harmful Algae Blooms (HAB) have been documented in Latin America and the Caribbean (LAC) for at least fifty years, but their impacts at social, ecological and economic levels are still little known. An analysis of available data and scientific literature reveals the main syndromes and causal organisms, with significant human intoxications and fatalities reported. Regional working groups and databases provide valuable information for understanding the trends and impacts of HAB events in the region.

HARMFUL ALGAE (2021)

Article Biotechnology & Applied Microbiology

Transcriptome survey, molecular identification, and expression analysis of stress-responsive genes in the toxic dinoflagellate Alexandrium pacificum under algicidal agents and metal stresses

Hui Wang et al.

Summary: The study characterized the transcriptome of marine dinoflagellate Alexandrium pacificum under various stresses, revealing numerous stress-responsive genes with potential diverse origins. Specifically, genes related to antioxidant enzymes, heat shock proteins, carotenoid biosynthesis, and other stress-responsive genes were identified. The findings suggest that A. pacificum possesses a range of stress-resistant genes that may aid in adaptation to new environments.

JOURNAL OF APPLIED PHYCOLOGY (2021)

Article Marine & Freshwater Biology

Preliminary result of de novo transcriptome sequencing of the marine toxic dinoflagellate Alexandrium catenella incubated under several different stresses

Hui Wang et al.

Summary: This study characterized the transcriptome of Alexandrium catenella isolated from Korean coastal waters, revealing the presence of numerous toxin- and cold response-related genes, as well as the conserved dinoflagellate spliced leader (dinoSL) indicating trans-splicing mRNA processing. Additionally, the detection of second or third dinoSL relicts in some genes suggests prior recycling between the genome and mRNA, potentially contributing to genome expansion in this species.

MARINE BIOLOGY (2021)

Article Chemistry, Medicinal

Low Temperature and Cold Stress Significantly Increase Saxitoxins (STXs) and Expression of STX Biosynthesis Genes sxtA4 and sxtG in the Dinoflagellate Alexandrium catenella

Hansol Kim et al.

Summary: The study evaluated the effects of temperature on cellular STXs and the expression of two core STX biosynthesis genes in toxic dinoflagellate A. catenella. Results showed that temperature significantly impacted the growth and STX production in A. catenella, as well as gene expression levels. This suggests that temperature may play a role in regulating toxicity and STX biosynthesis in dinoflagellates.

MARINE DRUGS (2021)

Review Biochemistry & Molecular Biology

Biosynthesis of marine toxins

Jonathan R. Chekan et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2020)

Review Microbiology

The Genetic Basis of Toxin Biosynthesis in Dinoflagellates

Arjun Verma et al.

MICROORGANISMS (2019)

Review Environmental Sciences

Paralytic Toxin Producing Dinoflagellates in Latin America: Ecology and Physiology

Christine J. Band-Schmidt et al.

FRONTIERS IN MARINE SCIENCE (2019)

Article Biochemistry & Molecular Biology

MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms

Sudhir Kumar et al.

MOLECULAR BIOLOGY AND EVOLUTION (2018)

Article Biochemistry & Molecular Biology

Insertions within the Saxitoxin Biosynthetic Gene Cluster Result in Differential Toxin Profiles

Alescia Cullen et al.

ACS CHEMICAL BIOLOGY (2018)

Article Marine & Freshwater Biology

Combined physical, chemical and biological factors shape Alexandrium ostenfeldii blooms in the Netherlands

Karen M. Brandenburg et al.

HARMFUL ALGAE (2017)

Article Biochemical Research Methods

Paralytic shellfish toxin biosynthesis in cyanobacteria and dinoflagellates: A molecular overview

Da-Zhi Wang et al.

JOURNAL OF PROTEOMICS (2016)

Article Engineering, Environmental

The sxt Gene and Paralytic Shellfish Poisoning Toxins as Markers for the Monitoring of Toxic Alexandrium Species Blooms

Antonella Penna et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2015)

Article Biochemistry & Molecular Biology

Gene duplication, loss and selection in the evolution of saxitoxin biosynthesis in alveolates

Shauna A. Murray et al.

MOLECULAR PHYLOGENETICS AND EVOLUTION (2015)

Article Biochemistry & Molecular Biology

Evolution of Saxitoxin Synthesis in Cyanobacteria and Dinoflagellates

Jeremiah D. Hackett et al.

MOLECULAR BIOLOGY AND EVOLUTION (2013)

Article Biochemistry & Molecular Biology

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

Kazutaka Katoh et al.

MOLECULAR BIOLOGY AND EVOLUTION (2013)

Review Chemistry, Medicinal

Evolution and Distribution of Saxitoxin Biosynthesis in Dinoflagellates

Russell J. S. Orr et al.

MARINE DRUGS (2013)

Review Microbiology

Dinoflagellate Genome Evolution

Jennifer H. Wisecaver et al.

ANNUAL REVIEW OF MICROBIOLOGY, VOL 65 (2011)

Article Biotechnology & Applied Microbiology

sxtA-Based Quantitative Molecular Assay To Identify Saxitoxin-Producing Harmful Algal Blooms in Marine Waters

Shauna A. Murray et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2011)

Article Biochemistry & Molecular Biology

Extraordinary Conservation, Gene Loss, and Positive Selection in the Evolution of an Ancient Neurotoxin

Shauna A. Murray et al.

MOLECULAR BIOLOGY AND EVOLUTION (2011)

Article Multidisciplinary Sciences

Discovery of Nuclear-Encoded Genes for the Neurotoxin Saxitoxin in Dinoflagellates

Anke Stuken et al.

PLOS ONE (2011)

Review Chemistry, Medicinal

Neurotoxic Alkaloids: Saxitoxin and Its Analogs

Maria Wiese et al.

MARINE DRUGS (2010)

Article Multidisciplinary Sciences

Origin of Saxitoxin Biosynthetic Genes in Cyanobacteria

Ahmed Moustafa et al.

PLOS ONE (2009)

Article Biotechnology & Applied Microbiology

Biosynthetic intermediate analysis and functional homology reveal a saxitoxin gene cluster in cyanobacteria

Ralf Kellmann et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2008)

Article Biochemical Research Methods

Clustal W and clustal X version 2.0

M. A. Larkin et al.

BIOINFORMATICS (2007)

Article Plant Sciences

Biochemical characterization of paralytic shellfish toxin biosynthesis in vitro

Ralf Kellmann et al.

JOURNAL OF PHYCOLOGY (2007)

Review Chemistry, Inorganic & Nuclear

Mechanism of taurine:: α-ketoglutarate dioxygenase (TauD) from Escherichia coli

JM Bollinger et al.

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (2005)

Review Plant Sciences

Dinoflagellates: A remarkable evolutionary experiment

JD Hackett et al.

AMERICAN JOURNAL OF BOTANY (2004)

Article Biochemistry & Molecular Biology

Gene conversion and GC-content evolution in mammalian Hsp70

G Kudla et al.

MOLECULAR BIOLOGY AND EVOLUTION (2004)

Article Biochemical Research Methods

MrBayes 3: Bayesian phylogenetic inference under mixed models

F Ronquist et al.

BIOINFORMATICS (2003)

Article Biochemistry & Molecular Biology

DNA helix: the importance of being GC-rich

AE Vinogradov

NUCLEIC ACIDS RESEARCH (2003)

Article Marine & Freshwater Biology

Strategies of marine dinoflagellate survival and some rules of assembly

TJ Smayda et al.

JOURNAL OF SEA RESEARCH (2003)