Drug Interactions What Are Important Drug Interactions for the Most Commonly Used Medications in Preventive Cardiology?

Significant drug interactions contribute to hospitalizations, mortality, and health care costs. They often are preventable with a basic understanding of pharmacokinetics and pharmacodynamics. More than quarter of Americans above the age of 40 years take a statin, the most commonly used lipid-lowering therapy in modern times. Because of their pharmacokinetics, statins interact with numerous other drugs and substances, often in a manner that differs from statin to statin. This article provides an overview of important drug interactions for the most commonly used medications in preventive cardiology, with an emphasis on clinically significant interactions involving statins.

Automated summary

Significant drug interactions can lead to hospitalizations, mortality, and healthcare costs, but can be prevented with a basic understanding of pharmacokinetics and pharmacodynamics. This article provides an overview of important drug interactions for commonly used medications in preventive cardiology, with a focus on clinically significant interactions involving statins.