NiO-MoO3 nanocomposite: A sensitive non-enzymatic sensor for glucose and urea monitoring

Binary transition metal nanocomposites have attracted much attention in the bio-sensing field due to their high activity. In this work, nickel oxide-molybdenum trioxide (NiO-MoO3) nanocomposite as a non-enzymatic sensor for glucose and urea oxidation is synthesized by a simple hydrothermal method. The nanocomposite synthesis is demonstrated using XRD, Raman, SEM, and TEM techniques. The electrochemical activity of the developed sensor is determined by cyclic voltammetry, differential pulse voltammetry, impedance spectroscopic, and chronoamperometry. The detection limit of NiO-MoO3 nanocomposite is found to be 0.86 and 0.85 mu M for urea and glucose, respectively. From the chronoamperometry test, this sensor maintains 66% and 65% of the initial current for urea and glucose, respectively, representing excellent stability. The results indicate that the NiO-MoO3 nanocomposite has an excellent potential for the detection of glucose and urea.

Automated summary

This study successfully synthesized a nickel oxide-molybdenum trioxide nanocomposite through a simple hydrothermal method and applied it as a non-enzymatic sensor for glucose and urea detection. The experimental results demonstrate that the nanocomposite exhibits excellent activity and stability.