期刊
MALARIA JOURNAL
卷 21, 期 1, 页码 -出版社
BMC
DOI: 10.1186/s12936-022-04131-8
关键词
Plasmodium knowlesi; Humans; Research; Malaria eradication
资金
- Ministry of Education Malaysia Long Term Research Grant Scheme [LRGS/1/2018/UM/01/1/2]
This article reviews recent studies on Plasmodium knowlesi, a zoonotic malaria parasite, summarizing key information and discussing knowledge gaps in research. It also describes the challenges and strategies required to control and eradicate this potentially fatal zoonosis.
Plasmodium knowlesi is a zoonotic malaria parasite that has gained increasing medical interest over the past two decades. This zoonotic parasitic infection is prevalent in Southeast Asia and causes many cases with fulminant pathology. Despite several biogeographical restrictions that limit its distribution, knowlesi malaria cases have been reported in different parts of the world due to travelling and tourism activities. Here, breakthroughs and key information generated from recent (over the past five years, but not limited to) studies conducted on P. knowlesi were reviewed, and the knowledge gap in various research aspects that need to be filled was discussed. Besides, challenges and strategies required to control and eradicate human malaria with this emerging and potentially fatal zoonosis were described.
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