相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Steric and electronic effects on the 1H hyperpolarisation of substituted pyridazines by signal amplification by reversible exchange
Peter J. Rayner et al.
MAGNETIC RESONANCE IN CHEMISTRY (2021)
A multisample 7 T dynamic nuclear polarization polarizer for preclinical hyperpolarized MR
Tian Cheng et al.
NMR IN BIOMEDICINE (2020)
Imaging breast cancer using hyperpolarized carbon-13 MRI
Ferdia A. Gallagher et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Increasing the sensitivity of hyperpolarized [15N2]urea detection by serial transfer of polarization to spin-coupled protons
Felix Kreis et al.
MAGNETIC RESONANCE IN MEDICINE (2020)
Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals
Edward M. Russak et al.
ANNALS OF PHARMACOTHERAPY (2019)
SABRE: Chemical kinetics and spin dynamics of the formation of hyperpolarization
Danila A. Barskiy et al.
PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY (2019)
Pharmacokinetics of the SABRE agent 4,6-d2-nicotinamide and also nicotinamide in rats following oral and intravenous administration
Inna Linnik et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2019)
High-throughput continuous-flow system for SABRE hyperpolarization
Petr Stepanek et al.
JOURNAL OF MAGNETIC RESONANCE (2019)
Achieving Biocompatible SABRE: An invitro Cytotoxicity Study
Anand Manoharan et al.
CHEMMEDCHEM (2018)
Facile Removal of Homogeneous SABRE Catalysts for Purifying Hyperpolarized Metronidazole, a Potential Hypoxia Sensor
Bryce E. Kidd et al.
JOURNAL OF PHYSICAL CHEMISTRY C (2018)
Rapid Catalyst Capture Enables Metal-Free para-Hydrogen-Based Hyperpolarized Contrast Agents
Danila A. Barskiy et al.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS (2018)
A simple hand-held magnet array for efficient and reproducible SABRE hyperpolarisation using manual sample shaking
Peter M. Richardson et al.
MAGNETIC RESONANCE IN CHEMISTRY (2018)
Metabolic and Molecular Imaging with Hyperpolarised Tracers
Jason Graham Skinner et al.
MOLECULAR IMAGING AND BIOLOGY (2018)
Fine-tuning the efficiency of para-hydrogen-induced hyperpolarization by rational N-heterocyclic carbene design
Peter J. Rayner et al.
NATURE COMMUNICATIONS (2018)
Quantification of hyperpolarisation efficiency in SABRE and SABRE-Relay enhanced NMR spectroscopy
Peter M. Richardson et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2018)
ParaHydrogen Hyperpolarized Substrates for Molecular Imaging Studies
Eleonora Cavallari et al.
ISRAEL JOURNAL OF CHEMISTRY (2017)
Direct Hyperpolarization of Nitrogen-15 in Aqueous Media with Parahydrogen in Reversible Exchange
Johannes F. P. Colell et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)
Harnessing polarisation transfer to indazole and imidazole through signal amplification by reversible exchange to improve their NMR detectability
Marianna Fekete et al.
MAGNETIC RESONANCE IN CHEMISTRY (2017)
Delivering strong 1H nuclear hyperpolarization levels and long magnetic lifetimes through signal amplification by reversible exchange
Peter J. Rayner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Achieving High 1H Nuclear Hyperpolarization Levels with Long Lifetimes in a Range of Tuberculosis Drug Scaffolds
Philip Norcott et al.
CHEMISTRY-A EUROPEAN JOURNAL (2017)
Achieving High Levels of NMR-Hyperpolarization in Aqueous Media With Minimal Catalyst Contamination Using SABRE
Wissam Iali et al.
CHEMISTRY-A EUROPEAN JOURNAL (2017)
The future of NMR-based metabolomics
John L. Markley et al.
CURRENT OPINION IN BIOTECHNOLOGY (2017)
Aqueous NMR Signal Enhancement by Reversible Exchange in a Single Step Using Water-Soluble Catalysts
Fan Shi et al.
JOURNAL OF PHYSICAL CHEMISTRY C (2016)
A simple analytical model for signal amplification by reversible exchange (SABRE) process
Danila A. Barskiy et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2016)
Utilisation of water soluble iridium catalysts for signal amplification by reversible exchange
M. Fekete et al.
DALTON TRANSACTIONS (2015)
Imaging Metabolism with Hyperpolarized 13C-Labeled Cell Substrates
Kevin M. Brindle
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Investigating pyridazine and phthalazine exchange in a series of iridium complexes in order to define their role in the catalytic transfer of magnetisation from para-hydrogen
Kate M. Appleby et al.
CHEMICAL SCIENCE (2015)
ParaHydrogen Induced Polarization of C-13 carboxylate resonance in acetate and pyruvate
Francesca Reineri et al.
NATURE COMMUNICATIONS (2015)
NMR Hyperpolarization Techniques for Biomedicine
Panayiotis Nikolaou et al.
CHEMISTRY-A EUROPEAN JOURNAL (2015)
Toward Biocompatible Nuclear Hyperpolarization Using Signal Amplification by Reversible Exchange: Quantitative in Situ Spectroscopy and High-Field Imaging
Jan-Bernd Hoevener et al.
ANALYTICAL CHEMISTRY (2014)
Design, synthesis and structure-activity relationships of novel 4-phenoxyquinoline derivatives containing pyridazinone moiety as potential antitumor agents
Shunguang Zhou et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
Achieving 1% NMR polarization in water in less than 1 min using SABRE
Haifeng Zeng et al.
JOURNAL OF MAGNETIC RESONANCE (2014)
Using Deuterium in Drug Discovery: Leaving the Label in the Drug
Thomas G. Gant
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Probing signal amplification by reversible exchange using an NMR flow system
Ryan E. Mewis et al.
MAGNETIC RESONANCE IN CHEMISTRY (2014)
Radial Spectroscopic MRI of Hyperpolarized [1-13C] Pyruvate at 7 Tesla
Marc S. Ramirez et al.
MAGNETIC RESONANCE IN MEDICINE (2014)
The role of level anti-crossings in nuclear spin hyperpolarization
Konstantin L. Ivanov et al.
PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY (2014)
Hyperpolarisation through reversible interactions with parahydrogen
Lyrelle S. Lloyd et al.
CATALYSIS SCIENCE & TECHNOLOGY (2014)
[2+2+2] Cycloadditions of Siloxy Alkynes with 1,2-Diazines: From Reaction Discovery to Identification of an Antiglycolytic Chemotype
Timothy J. Montavon et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
3-[(6-Arylamino)pyridazinylamino]benzoic acids: design, synthesis and in vitro evaluation of anticancer activity
Khaled A. M. Abouzid et al.
ARCHIVES OF PHARMACAL RESEARCH (2013)
Iridium(III) Hydrido N-Heterocyclic Carbene-Phosphine Complexes as Catalysts in Magnetization Transfer Reactions
Marianna Fekete et al.
INORGANIC CHEMISTRY (2013)
Optimized production of hyperpolarized 129Xe at 2 bars for in vivo lung magnetic resonance imaging
Graham Norquay et al.
JOURNAL OF APPLIED PHYSICS (2013)
Kinetic deuterium isotope effects in cytochrome P450 oxidation reactions
F. Peter Guengerich
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS (2013)
Isotope Effects as Probes for Enzyme Catalyzed Hydrogen-Transfer Reactions
Daniel Roston et al.
MOLECULES (2013)
Heavy drugs draw heavy interest from pharma backers
Alla Katsnelson
NATURE MEDICINE (2013)
Design and synthesis of some thieno[2,3-c]pyridazine derivatives of expected anticancer activity
Afaf K. El-Ansary et al.
MEDICINAL CHEMISTRY RESEARCH (2013)
Simultaneous Imaging of Lung Structure and Function with Triple-Nuclear Hybrid MR Imaging
Jim M. Wild et al.
RADIOLOGY (2013)
Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1-13C]Pyruvate
Sarah J. Nelson et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Copper-Catalyzed Tandem C-N Bond Formation: An Efficient Annulative Synthesis of Functionalized Cinnolines
Catherine J. Ball et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Synthesis and biological evaluation of isoxazolo[4,5-d]pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents
Keriman Ozadali et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
Design, synthesis and antiviral activity of novel pyridazines
Ziwen Wang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
Hyperpolarized 129Xe gas lung MRI-SNR and T2*comparisons at 1.5 T and 3 T
Xiaojun Xu et al.
MAGNETIC RESONANCE IN MEDICINE (2012)
Iridium N-Heterocyclic Carbene Complexes as Efficient Catalysts for Magnetization Transfer from para-Hydrogen
Michael J. Cowley et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Metabolism and Disposition of the Thienopyridine Antiplatelet Drugs Ticlopidine, Clopidogrel, and Prasugrel in Humans
Nagy A. Farid et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2010)
Dual-Band Water and Lipid Suppression for MR Spectroscopic Imaging at 3 Tesla
He Zhu et al.
MAGNETIC RESONANCE IN MEDICINE (2010)
Storage of nuclear magnetization as long-lived singlet order in low magnetic field
Giuseppe Pileio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
THE KINETIC ISOTOPE EFFECT IN THE SEARCH FOR DEUTERATED DRUGS
Liming Shao et al.
DRUG NEWS & PERSPECTIVES (2010)
A theoretical basis for spontaneous polarization transfer in non-hydrogenative parahydrogen-induced polarization
Ralph W. Adams et al.
JOURNAL OF CHEMICAL PHYSICS (2009)
Cryocoolers: the state of the art and recent developments
Ray Radebaugh
JOURNAL OF PHYSICS-CONDENSED MATTER (2009)
Reversible Interactions with para-Hydrogen Enhance NMR Sensitivity by Polarization Transfer
Ralph W. Adams et al.
SCIENCE (2009)
Parahydrogen-based NMR methods as a mechanistic probe in inorganic chemistry
Simon B. Duckett et al.
COORDINATION CHEMISTRY REVIEWS (2008)
Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy
Sam E. Day et al.
NATURE MEDICINE (2007)
Pyridazine derivatives and related compounds, Part 17:: The synthesis of some 3-substituted pyridazino[3′, 4′:3,4]pyrazolo [5,1-c]-1,2,4-triazines and their antimicrobial activity
F El-Mariah et al.
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS (2006)
Achieving sufficient spectral bandwidth for volumetric 1H echo-planar spectroscopic imaging at 4 Tesla
A Ebel et al.
MAGNETIC RESONANCE IN MEDICINE (2005)
Beyond the T1 limit:: Singlet nuclear spin states in low magnetic fields -: art. no. 153003
M Carravetta et al.
PHYSICAL REVIEW LETTERS (2004)
Transfer of para-hydrogen spin order into polarization by diabatic field cycling
H Jóhannesson et al.
COMPTES RENDUS PHYSIQUE (2004)
Long-lived nuclear spin states in high-field solution NMR
M Carravetta et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Increase in signal-to-noise ratio of >10,000 times in liquid-state NMR
JH Ardenkjaer-Larsen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Reduction of spectral ghost artifacts in high-resolution echo-planar spectroscopic Imaging of water and fat resonances
WL Du et al.
MAGNETIC RESONANCE IN MEDICINE (2003)
The use of deuterium isotope effects to probe the active site properties, mechanism of cytochrome P450-catalyzed reactions, and mechanisms of metabolically dependent toxicity
SD Nelson et al.
DRUG METABOLISM AND DISPOSITION (2003)
分享论文
