Antibacterial and antibiofilm activities of some plant essential oils and synergistic effects of cinnamon essential oil with vancomycin against Clostridioides difficile: in vitro study

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Alimentary and Pharmaceutical Approach to Natural Antimicrobials against Clostridioides difficile Gastrointestinal Infection

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Summary: The incidence of CDI continues to rise due to factors such as antibiotic use and microbial imbalance. Natural bioactives from vegetables and marine sources are seen as effective alternative therapies in combating CDI.

FOODS (2021)

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Review Forestry

The Potential Role of Cinnamon in Human Health

Natalia Blaszczyk et al.

Summary: Cinnamon, a tropical plant in the Lauraceae family, contains biologically active compounds with antioxidant, anti-inflammatory, and antibacterial properties. It has been used for centuries in traditional medicine to treat diabetes and other diseases. In folk medicine, cinnamon is also used to treat respiratory and digestive disorders.

FORESTS (2021)

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Review Microbiology

Biofilm regulation in Clostridioides difficile: Novel systems linked to hypervirulence

Megan G. Taggart et al.

Summary: Clostridiodes difficile is ranked as an urgent threat by CDC due to its prevalence in healthcare settings and its association with antibiotic-associated gastrointestinal diseases. The role of biofilm formation in the pathogenesis of C. difficile infection is still not fully understood, but it is believed to play a significant role in disease recurrence. Various factors, such as motility and adhesion, influence biofilm formation in C. difficile, making the regulatory system complex and multifactorial. Further research is needed to better understand biofilm regulation in different strains of C. difficile and its implications for disease management.

PLOS PATHOGENS (2021)

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Article Infectious Diseases

Curcumin: A natural derivative with antibacterial activity against Clostridium difficile

Deepansh Mody et al.

JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE (2020)

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Article Microbiology

Prevalence and characterization of Clostridioides difficile isolates from retail food products (vegetables and meats) in Japan

Masaru Usui et al.

ANAEROBE (2020)

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Article Integrative & Complementary Medicine

Chemical Composition and Antioxidant, Antimicrobial, and Antiproliferative Activities of Cinnamomum zeylanicum Bark Essential Oil

Behrooz Alizadeh Behbahani et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2020)

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Article Multidisciplinary Sciences

High prevalence of Clostridiodes diffiicle PCR ribotypes 001 and 126 in Iran

Akram Baghani et al.

SCIENTIFIC REPORTS (2020)

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Article Infectious Diseases

Antimicrobial Spectrum of Titroleane™: A New Potent Anti-Infective Agent

Bianca Johansen et al.

ANTIBIOTICS-BASEL (2020)

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Review Public, Environmental & Occupational Health

Antimicrobial resistance inClostridioides(Clostridium)difficilederived from humans: a systematic review and meta-analysis

Mohammad Sholeh et al.

ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL (2020)

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Review Microbiology

Natural Anti-biofilm Agents: Strategies to Control Biofilm-Forming Pathogens

Rojita Mishra et al.

FRONTIERS IN MICROBIOLOGY (2020)

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Review Integrative & Complementary Medicine

Developing natural products as potential anti-biofilm agents

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CHINESE MEDICINE (2019)

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Review Biotechnology & Applied Microbiology

Clostridium difficile Infections: A Global Overview of Drug Sensitivity and Resistance Mechanisms

Saeed S. Banawas

BIOMED RESEARCH INTERNATIONAL (2018)

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Article Agricultural Engineering

The most aroma-active compounds in shade-dried aerial parts of basil obtained from Iran and Turkey

Ahmet Salih Sonmezdag et al.

INDUSTRIAL CROPS AND PRODUCTS (2018)

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Article Biotechnology & Applied Microbiology

Antimicrobial activity of natural products against Clostridium difficile invitro

N. Roshan et al.

JOURNAL OF APPLIED MICROBIOLOGY (2017)

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Article Infectious Diseases

Antimicrobial susceptibility of Clostridium difficile isolates in Israel

Linda Tkhawkho et al.

JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE (2017)

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Review Integrative & Complementary Medicine

Antimicrobial Properties of Plant Essential Oils against Human Pathogens and Their Mode of Action: An Updated Review

Mallappa Kumara Swamy et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2016)

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Article Multidisciplinary Sciences

Highly Divergent Clostridium difficile Strains Isolated from the Environment

Sandra Janezic et al.

PLOS ONE (2016)

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Synergistic Effects of Chinese Herbal Medicine: A Comprehensive Review of Methodology and Current Research

Xian Zhou et al.

FRONTIERS IN PHARMACOLOGY (2016)

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Review Infectious Diseases

Antimicrobial Resistance and Reduced Susceptibility in Clostridium difficile: Potential Consequences for Induction, Treatment, and Recurrence of C. difficile Infection

Simon D. Baines et al.

ANTIBIOTICS-BASEL (2015)

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Article Integrative & Complementary Medicine

Biofilm formation of Clostridium difficile and susceptibility to Manuka Honey

Eric N. Hammond et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2014)

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Article Biochemistry & Molecular Biology

Carvacrol and trans-Cinnamaldehyde Reduce Clostridium difficile Toxin Production and Cytotoxicity in Vitro

Shankumar Mooyottu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

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Article Microbiology

Study of the frequency of Clostridium difficile tcdA, tcdB, cdtA and cdtB genes in feces of Calves in south west of Iran

Abbas Doosti et al.

ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS (2014)

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Article Microbiology

Multiple Factors Modulate Biofilm Formation by the Anaerobic Pathogen Clostridium difficile

Tanja Dapa et al.

JOURNAL OF BACTERIOLOGY (2013)

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Article Infectious Diseases

Antimicrobial susceptibility testing of Clostridium difficile using EUCAST epidemiological cut-off values and disk diffusion correlates

L. T. Erikstrup et al.

CLINICAL MICROBIOLOGY AND INFECTION (2012)

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Article Microbiology

Clostridium difficile in seafood and fish

Devon Metcalf et al.

ANAEROBE (2011)

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Article Immunology

Clostridium difficile in Retail Meat Products, USA, 2007

J. Glenn Songer et al.

EMERGING INFECTIOUS DISEASES (2009)

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Article Chemistry, Medicinal

Composition and antimicrobial activity of Juniperus excelsa essential oil

M. Unlu et al.

CHEMISTRY OF NATURAL COMPOUNDS (2008)

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Article Food Science & Technology

Trans-cinnamaldehyde from Cinnamomum zeylanicum bark essential oil reduces the clindamycin resistance of Clostridium difficile in vitro

A. R. Shahverdi et al.

JOURNAL OF FOOD SCIENCE (2007)

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Review Microbiology

Melaleuca alternifolia (tea tree) oil: a review of antimicrobial and other medicinal properties

CF Carson et al.

CLINICAL MICROBIOLOGY REVIEWS (2006)

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Antibacterial and antibiofilm activities of some plant essential oils and synergistic effects of cinnamon essential oil with vancomycin against Clostridioides difficile: in vitro study

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