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Article
Infectious Diseases
Lamprini Veneti et al.
Summary: A study found that the Omicron variant of COVID-19 has a 73% reduced risk of hospitalization compared to the Delta variant. Omicron cases who had received two doses of the vaccine 7-179 days before diagnosis had a lower risk compared to Delta (66% vs 93%), while those who received three doses had a similar risk reduction (86% vs 88%).
Letter
Medicine, General & Internal
Ana Cecilia Ulloa et al.
Summary: This study compares hospitalizations and deaths associated with SARS-CoV-2 Omicron variant to those of matched patients infected with the Delta variant.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)
Article
Medicine, General & Internal
Nicole Wolter et al.
Summary: According to data analysis from South Africa, individuals infected with the omicron variant have a lower likelihood of hospitalization compared to those infected with non-omicron variants. Furthermore, individuals infected with the omicron variant have a lower odds of severe disease compared to individuals infected with the earlier delta variant.
Article
Multidisciplinary Sciences
Bo Meng et al.
Summary: The Omicron variant of SARS-CoV-2 has a higher affinity for ACE2 and can evade neutralizing antibodies more effectively compared to the Delta variant. A third dose of mRNA vaccine can provide enhanced protection. Omicron has lower replication in lung and gut cells and less efficiently cleaves its spike protein compared to Delta.
Article
Multidisciplinary Sciences
Kenrie P. Y. Hui et al.
Summary: SARS-CoV-2 variants pose a threat to global public health. The Omicron variant replicates faster in bronchi but less efficiently in the lung parenchyma compared to other variants. All variants of concern have similar cellular tropism.
Article
Infectious Diseases
F. Abdullah et al.
Summary: This study analyzed the clinical data of COVID-19 patients admitted to a hospital in Tshwane during the Omicron wave, and found that the severity of the disease was decreased compared to previous waves, with lower death rates and ICU admissions.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Infectious Diseases
Katherine A. Twohig et al.
Summary: A study in England found that patients with COVID-19 infected with the delta variant were more likely to be admitted to hospital or attend emergency care compared to those infected with the alpha variant. This suggests that outbreaks of the delta variant in unvaccinated populations may pose a greater burden on healthcare services.
LANCET INFECTIOUS DISEASES
(2022)
Article
Medicine, General & Internal
David N. Fisman et al.
Summary: Research in Ontario, Canada, showed that new variants of concern (VOCs) of SARS-CoV-2 have higher risks of hospitalization, ICU admission, and death compared to non-VOC strains, with the Delta variant showing the most pronounced increase in risk.
CANADIAN MEDICAL ASSOCIATION JOURNAL
(2021)
Letter
Infectious Diseases
Peter Bager et al.
LANCET INFECTIOUS DISEASES
(2021)
Article
Public, Environmental & Occupational Health
T. Clare et al.
Summary: This study evaluated the completeness and timeliness of the surveillance of SARS-CoV-2 infection in England, showing high completeness of data and improving timeliness of reporting.
Article
Infectious Diseases
Alex Bhattacharya et al.
Summary: In England, hospital-onset probable and definite cases accounted for 5.3% of all laboratory-confirmed COVID-19 cases, with community-onset community-acquired cases being the highest proportion. Hospital-associated SARS-CoV-2 infections were identified in single and multi-site hospital-based studies, with up to 1 in 6 infections among hospitalised patients being attributed to nosocomial transmission.
JOURNAL OF INFECTION
(2021)
Letter
Medicine, General & Internal
Aziz Sheikh et al.
Article
Infectious Diseases
Peter Bager et al.
Summary: The study conducted in Denmark found that individuals infected with the B.1.1.7 lineage of SARS-CoV-2 had a higher risk of hospitalisation for COVID-19 compared to those with other lineages. While the overall number of hospitalisations decreased during the study period, the proportion of individuals infected with B.1.1.7 significantly increased. The findings suggest implications for hospital preparedness and understanding the impact of the epidemic in areas with the dominant presence of B.1.1.7.
LANCET INFECTIOUS DISEASES
(2021)
