4.7 Editorial Material

Americentrism in estimation of glomerular filtration rate equations

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Article Medicine, General & Internal

Development and Validation of a Modified Full Age Spectrum Creatinine-Based Equation to Estimate Glomerular Filtration Rate A Cross-sectional Analysis of Pooled Data

Hans Pottel et al.

Summary: A new SCr-based equation, combining design features of the FAS and CKD-EPI equations, has been developed and validated to estimate glomerular filtration rate more accurately, especially during the transition from adolescence to adulthood. The equation shows low bias and fewer estimation errors across the full age spectrum.

ANNALS OF INTERNAL MEDICINE (2021)

Review Urology & Nephrology

The ⟪ race ⟫ correction in estimating glomerular filtration rate: an European point of view

Pierre Delanaye et al.

Summary: The ongoing debate about the race coefficient in the modification of diet for renal diseases and chronic kidney disease is centered on whether it is necessary for black individuals. Recent studies have shown that the race coefficient is inaccurate for European and African black populations, suggesting that it might be specific to black Americans. Criticism has arisen over the correction at the glomerular filtration rate level, with calls for dedicated studies in both Europe and the USA.

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2021)

Article Medicine, General & Internal

Race, Genetic Ancestry, and Estimating Kidney Function in CKD

C. Hsu et al.

Summary: The study found that using serum creatinine levels to estimate GFR without taking race (or genetic ancestry) into account led to systematic misclassification. Estimating GFR with cystatin C produced similar results while eliminating negative consequences of race-based approaches.

NEW ENGLAND JOURNAL OF MEDICINE (2021)