4.1 Article

Antibiotic resistance of Pseudomonas aeruginosa isolated from hospital wastewater in the Czech Republic

期刊

JOURNAL OF WATER AND HEALTH
卷 20, 期 4, 页码 692-701

出版社

IWA PUBLISHING
DOI: 10.2166/wh.2022.101

关键词

antibiotic resistance; hospital wastewater; multidrug resistance; Pseudomonas aeruginosa

向作者/读者索取更多资源

This study evaluated the antibiotic resistance profiles of Pseudomonas aeruginosa in untreated hospital effluents in the Czech Republic. The findings revealed the presence of antibiotic-resistant strains in hospital wastewater that were resistant to clinically relevant antipseudomonal drugs. Inadequate treatment of hospital wastewater can lead to the direct release of resistant bacteria into public sewer networks, potentially facilitating the spread of antibiotic resistance.
Resistant bacteria may leave the hospital environment through wastewater. The opportunistic pathogen Pseudomonas aeruginosa, due to its intrinsic resistance to many antibiotics and its ability to easily acquire antibiotic resistance determinants, poses a significant threat to public health. The aim of this study was to evaluate the antibiotic resistance profiles of cultivated P. aeruginosa in untreated hospital effluents in the Czech Republic. Fifty-nine P. aeruginosa strains isolated from six hospital wastewaters were tested for antimicrobial susceptibility through the disc diffusion method against seven antimicrobial agents. Resistance was found in all antibiotics tested. The highest resistance values were observed for ciprofloxacin (30.5%), gentamicin (28.8%), and meropenem (27.2%). The P. aeruginosa isolates also exhibited resistance to ceftazidime (11.5%), amikacin (11.5%), piperacillin-tazobactam (11.5%), and aztreonam (8.5%). Seventeen strains of P. aeruginosa (28.8%) were classified as multidrug-resistant (MDR). The results of this study revealed that antibiotic-resistant strains are commonly present in hospital wastewater and are resistant to clinically relevant antipseudomonal drugs. In the absence of an appropriate treatment process for hospital wastewater, resistant bacteria are released directly into public sewer networks, where they can serve as potential vectors for the spread of antibiotic resistance.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.1
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据