期刊
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
卷 33, 期 5, 页码 505-509出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jvir.2022.02.004
关键词
-
资金
- Royal Australian and New Zealand College of Radiologists
This study demonstrated quantitatively that long-term immune function remains after splenic artery embolization for blunt abdominal trauma based on the levels of IgM memory B cells.
Splenic artery embolization (SAE) plays a critical role in the treatment of high-grade splenic injury not requiring emergent laparotomy. SAE preserves splenic tissue, and growing evidence demonstrates preserved short-term splenic immune function after SAE. However, long-term function is less studied. Patients who underwent SAE for blunt abdominal trauma over a 10-year period were contacted for long-term follow-up. Sixteen participants (sex: women, 10, and men, 6; age: median, 34 years, and range, 18-67 years) were followed up at a median of 7.7 years (range, 4.7-12.8 years) after embolization. Splenic lacerations were of American Association for the Surgery of Trauma grades III to V, and 14 procedures involved proximal embolization. All individuals had measurable levels of IgM memory B cells (median, 14.30 as %B cells), splenic tissue present on ultrasound (median, 122 mL), and no history of severe infection since SAE. In conclusion, this study quantitatively demonstrated that long-term immune function remains after SAE for blunt abdominal trauma based on the IgM memory B cell levels.
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