4.5 Article

Discriminator for Cutaneous Leishmaniasis Using MALDI-MSI in a Murine Model

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Analytical

Implications of Peak Selection in the Interpretation of Unsupervised Mass Spectrometry Imaging Data Analyses

Teresa Murta et al.

Summary: Mass spectrometry imaging generates complex spectral and spatial data, which are often analyzed using unsupervised machine learning techniques. This study focuses on the impact of peak selection choices on the interpretation of analyses, highlighting the importance of selecting peaks based on specific criteria for more valuable and easier-to-interpret results.

ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Analytical

Structure-Preserving and Perceptually Consistent Approach for Visualization of Mass Spectrometry Imaging Datasets

Anastasia Sarycheva et al.

Summary: Mass spectrometry imaging (MSI) is a vital tool for visualizing compound distributions in biological tissues, allowing for the investigation of molecular organization and detection of abnormal regions. However, the complexity of spectral data presents challenges in analyzing large datasets and conducting exploratory visualization. Techniques such as principal component analysis and non-negative matrix factorization are used to address these challenges in MSI data analysis.

ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Analytical

Spatial Segmentation of Mass Spectrometry Imaging Data by Combining Multivariate Clustering and Univariate Thresholding

Hang Hu et al.

Summary: This study introduces an unsupervised spatial segmentation approach that combines multivariate clustering and univariate thresholding to effectively segment mass spectrometry imaging (MSI) data, demonstrating its performance and robustness on two tissue sections data sets acquired with different spatial resolutions. The resulting segmentation maps are easy to interpret and project onto the known anatomical regions of the tissue.

ANALYTICAL CHEMISTRY (2021)

Review Spectroscopy

Unsupervised machine learning for exploratory data analysis in imaging mass spectrometry

Nico Verbeeck et al.

MASS SPECTROMETRY REVIEWS (2020)

Review Medicine, General & Internal

Leishmaniasis

Sakib Burza et al.

LANCET (2018)

Review Radiology, Nuclear Medicine & Medical Imaging

Mass Spectrometry Imaging and Integration with Other Imaging Modalities for Greater Molecular Understanding of Biological Tissues

Tiffany Porta Siegel et al.

MOLECULAR IMAGING AND BIOLOGY (2018)

Review Chemistry, Analytical

Mass Spectrometry Imaging: A Review of Emerging Advancements and Future Insights

Amanda Rae Buchberger et al.

ANALYTICAL CHEMISTRY (2018)

Article Biochemistry & Molecular Biology

Murine cutaneous leishmaniasis investigated by MALDI mass spectrometry imaging

Fernanda Negrao et al.

MOLECULAR BIOSYSTEMS (2017)

Review Chemistry, Analytical

Ambient Mass Spectrometry Imaging Using Direct Liquid Extraction Techniques

Julia Laskin et al.

ANALYTICAL CHEMISTRY (2016)

Article Multidisciplinary Sciences

Data-driven identification of prognostic tumor subpopulations using spatially mapped t-SNE of mass spectrometry imaging data

Walid M. Abdelmoula et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Review Infectious Diseases

A Historical Overview of the Classification, Evolution, and Dispersion of Leishmania Parasites and Sandflies

Mohammad Akhoundi et al.

PLOS NEGLECTED TROPICAL DISEASES (2016)

Article Medicine, General & Internal

Leishmaniasis: clinical syndromes and treatment

B. S. McGwire et al.

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE (2014)

Article Public, Environmental & Occupational Health

Randomized, Double-Blinded, Phase 2 Trial of WR 279,396 (Paromomycin and Gentamicin) for Cutaneous Leishmaniasis in Panama

Nestor Sosa et al.

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2013)

Review Biochemical Research Methods

MALDI imaging mass spectrometry: statistical data analysis and current computational challenges

Theodore Alexandrov

BMC BIOINFORMATICS (2012)

Article Chemistry, Medicinal

Novel pentamidine derivatives: Synthesis, anti-tumor properties and polynucleotide-binding activities

Ivana Jarak et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2011)

Review Chemistry, Multidisciplinary

Mass Spectrometric Imaging for Biomedical Tissue Analysis

Kamila Chughtai et al.

CHEMICAL REVIEWS (2010)

Review Dermatology

Cutaneous leishmaniasis: advances in disease pathogenesis, diagnostics and therapeutics

M. Ameen

CLINICAL AND EXPERIMENTAL DERMATOLOGY (2010)

Review Dermatology

New World cutaneous leishmaniasis: Updated review of current and future diagnosis and treatment

Panagiotis Mitropoulos et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2010)

Article Biochemical Research Methods

Improved MALDI-TOF Imaging Yields Increased Protein Signals at High Molecular Mass

Barbara D. Leinweber et al.

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2009)

Review Biochemistry & Molecular Biology

MALDI-MS-based imaging of small molecules and proteins in tissues

Michelle L. Reyzer et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2007)

Review Dermatology

CUTANEOUS LEISHMANIASIS

Domingo Garcia-Almagro

ACTAS DERMO-SIFILIOGRAFICAS (2005)

Article Chemistry, Analytical

Identification of cellular sections with imaging mass spectrometry following freeze fracture

TP Roddy et al.

ANALYTICAL CHEMISTRY (2002)