Copper-Catalyzed Regiodivergent and Enantioselective Hydrosilylation of Allenes

A copper-catalyzed regiodivergent hydrosilylation of a wide range of simple allenes is reported. Linear and branched allylsilanes were formed by judicious choice of solvents. Furthermore, branched allylsilanes were obtained with high enantioselectivity (up to 97% enantiomeric excess) with the aid of a C2-symmetric bisphosphine ligand in the unprecedented asymmetric allene hydrosilylation.

Automated summary

A copper-catalyzed regiodivergent hydrosilylation of a wide range of simple allenes is reported. Linear and branched allylsilanes can be obtained by choosing suitable solvents. Moreover, high enantioselectivity branch allylsilanes (up to 97% enantiomeric excess) can be achieved in the unprecedented asymmetric allene hydrosilylation with a C2-symmetric bisphosphine ligand.