☆ 4.5 Article

The Impact of Osteoporosis on Adverse Outcomes After Short Fusion for Degenerative Lumbar Disease

JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS (2022)

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Summary: This study confirms the efficacy of teriparatide in improving fusion rates in osteoporotic patients undergoing spinal fusion surgery. Patients treated with teriparatide had significantly higher rates of lumbar spinal fusion compared to those not receiving the treatment, with a greater likelihood of fusion compared to bisphosphonate and placebo cohorts. The treatment also showed benefits in reducing subsequent vertebral fractures, sagittal malalignment, limb VAS, and spinal VAS. Further research is needed to determine the optimal duration of treatment and timing of surgery.

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